Abstract: A method for treating a mineral composition containing iron, arsenic or other Group VA compounds comprises milling the mineral composition to a particle size of P80 of less than 25 ?m and leaching the mineral composition in the presence of lime and/or limestone and a soluble alkali complexing agent and in the presence of an oxygen containing gas at a pH in the range of from 3.5 to 6.

Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: A receptacle connector includes a housing having a slot configured to receive a mating connector therein. Signal contacts are held by the housing. The signal contacts include signal mating segments and signal mounting segments. The signal mating segments include signal mating interfaces that are exposed within the slot for engagement with the mating connector. Ground contacts are held by the housing. The ground contacts include ground mating segments and ground mounting segments. The ground mating segments include ground mating interfaces that are exposed within the slot for engagement with the mating connector. A ground bus electrically commons the ground contacts with each other. The ground contacts and the ground bus are integrally fabricated as a single, unitary, continuous structure.

Abstract: A connector sub-assembly includes a dielectric carrier, plural signal conductors, and a ground frame. The dielectric carrier is defined by first and second overmolded bodies that engage one another at an overmold interface. An intermediate segment of each signal conductor is encased within the dielectric carrier. The ground frame is held between the first and second overmolded bodies at the overmold interface. The ground frame includes a ground bus bar encased within the dielectric carrier and plural ground conductors extending from the ground bus bar. The second overmolded body is formed in-situ on an inner side of the first overmolded body. An inner side of the second overmolded body at the overmold interface is partially defined by a profile of the inner side of the first overmolded body and partially defined by the ground frame.

Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: In one embodiment, a connector assembly comprises: a connector; and a pair of side collectors, each comprising a connector engagement region having a size and geometry to mate with the connector so as to hold ends of two adjacent panels together; and a panel engagement region comprising a receiving area and having a size to attach onto an edge of the panel; and a clip, wherein the clip has a base that can be attached to a support, an engagement, and a stem extending therebetween, wherein the engagement has an extension projecting from a side of the engagement, wherein the panel engagement region further comprises an opening in a joint wall on a side of the panel engagement region opposite the receiving area, wherein the opening is configured to receive the extension of the engagement.

Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

Abstract: An electric clipper having a visual feedback system for displaying the running RPMs thereof. The electric clipper having a visual feedback system comprises a base hair clipper which includes an external display screen. The base hair clipper is constructed as conventional electric hair clippers and includes tuner is connected to the base hair clipper's internal motor and enables the operating speed of the motor to be adjusted. An internal tachometer is additionally included in the base hair clipper to generate measurements of the rotation speed of the motor. Such measurements are displayed on the external display, defined as an LED display. The LED display is configured to provide a digital readout of the RPMs of the motor in real time and provide a color coded output corresponding to a general range of RPMs.

Abstract: Decellularization methods for tissue are provided. The method can include: exposing a tissue to a water-saturated, supercritical CO2. The method can further comprise, prior to exposing the tissue to the water-saturated, supercritical CO2, saturating a stream of supercritical CO2. The tissue can be exposed to the water-saturated, supercritical CO2 at a treatment temperature of about 35° C. to about 40° C. (e.g., about 37° C.). In one embodiment, the water-saturated, supercritical CO2 is completely saturated with water at the treatment temperature. The tissue can be exposed to the water-saturated, supercritical CO2 at a constant flow rate, such as less than 3 mL/min (e.g., about 0.5 mL/min to about 2.5 mL/min).

Abstract: A structure comprising a plurality of plies of fiber-reinforced composite material, each ply having a ply orientation defined by a principal stiffness direction of the ply. The structure has a first region and a second region, each region comprising N1 primary plies, N4 cross plies with a ply orientation substantially perpendicular to the primary plies, N2 positive-angled bias plies with a ply orientation at a positive acute angle to the primary plies, and N3 negative-angled bias plies with a ply orientation substantially perpendicular to the positive-angled bias plies. The ply orientation of the primary plies in each region is more closely aligned with a primary axis of the structure than the cross plies or the bias plies. N1=N4 in the first region but not in the second N region, and N2=N3 in the second region but not in the first region. In each of the two regions, one ply set is balanced and the other ply set is un-balanced.

Abstract: In one embodiment, a connector assembly comprises: a connector; and a pair of side collectors, each comprising a connector engagement region having a size and geometry to mate with the connector so as to hold ends of two adjacent panels together; and a panel engagement region comprising a receiving area and having a size to attach onto an edge of the panel; and a clip, wherein the clip has a base that can be attached to a support, an engagement, and a stem extending therebetween, wherein the engagement has an extension projecting from a side of the engagement, wherein the panel engagement region further comprises an opening in a joint wall on a side of the panel engagement region opposite the receiving area, wherein the opening is configured to receive the extension of the engagement.

Abstract: Power connector assembly including a power contact having a base portion and opposing contact springs that project from the base portion along a mating axis. The contact springs oppose each other across a receiving space and are configured to engage a common conductive component that is inserted into the receiving space in a direction along the mating axis. The power connector assembly also includes an alignment body that has a support plate and a coupling member that engages and holds the power contact. The support plate includes an elongated slot and a contact window. The coupling member holds the power contact in a designated position relative to the support plate, wherein the base portion extends into the contact window when in the designated position and the contact springs extend along and substantially parallel to the elongated slot when in the designated position.

Abstract: A railing and baluster plug system that facilitates installation of balusters at a plurality of angular orientations, such as installations for level railing and installations for non-level or angled railings such as for stairs. The baluster plugs are configured to cooperate with the balusters and include both a level mounting surface and an angled mounting surface for alternatively mounting the balusters in a level or an angled orientation.

Abstract: A process for treating a mixed sulphidic material containing lead sulphide and at least one other metal sulphide. The process includes the steps of subjecting the mixed sulphidic material to selective oxidation such that lead sulphide in the material is oxidised to form an oxidized lead compound while substantial oxidation of the at least one other metal sulphide is avoided, and separating the oxidized lead compound from the at least one other metal sulphide. The oxidized lead compound may be separated by flotation wherein the oxidized lead compound reports to the tailings and the at least one other metal sulphide reports to the concentrate (froth).

Abstract: A method, system and portable digital media for processing an interactive game of chance enables an alternative gambling experience. The method includes coupling a portable digital media, including the interactive game of chance, with a consumer device; viewing visual components of the interactive game of chance, wherein the visual components are used to define a predetermined outcome of the interactive game of chance; interacting with the visual components through the consumer device; and viewing the predetermined outcome of the interactive game of chance.

Abstract: Purified Ref polypeptides with increased nuclease site-specific targeting activity, recombinant nucleic acids and cells for expression of such Ref polypeptides, and methods for using the Ref polypeptides in combination with RecA protein and variants thereof to effect targeted nuclease cleavage of a DNA duplex are disclosed.

Abstract: A process for treating a mixed sulphidic material containing lead sulphide and at least one other metal sulphide. The process includes the steps of subjecting the mixed sulphidic material to selective oxidation such that lead sulphide in the material is oxidised to form an oxidised lead compound while substantial oxidation of the at least one other metal sulphide is avoided, and separating the oxidized lead compound from the at least one other metal sulphide. The oxidized lead compound may be separated by flotation wherein the oxidized lead compound reports to the tailings and the at least one other metal sulphide reports to the concentrate (froth).

Abstract: A view item page that is descriptive of a current item may be displayed in response to a request to view a description of the current item. The view item page may include a control that is operable to display recommendations of further items similar to the current item that is described in the view item page. Upon detecting that a user has operated the control included in the view item page, the recommendations of the further items may be generated based on the current item described in the view item page. Moreover, the generated recommendations may be presented to the user that operated the control.

Abstract: The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.