Abstract: Conventional, manual identification and scoring of a whole slide image (WSI) to detect Cytokeratin 17 (K17) expression has limitations in terms of lower accuracy in the medium grade cases, slower turn-around time, and high inter and intra-observer variability. Each WSI can take a pathologist six to ten minutes to examine. This is because the brown color staining indicating the presence of K17 may be one of thousands or tens of thousands or other expressions present on the slide. Apparatus and methods are provided for an artificial intelligence (AI) solution that identifies and quantifies positively stained urothelial cells in WSI of urine cytology to aid the diagnosis of urinary bladder carcinoma. An illustrative AI solution may include one or computer models that are programmed to run one more machine learning (ML) models. The ML models may be trained to recognize subtle and complex patterns and features associated with specific diseases.

Abstract: Disclosed herein are an exemplary apparatus, system, and methods (e.g., Tactical Passive RFID transponder gloves with Morphological Actuation) comprising a glove made predominately of a resistive fabric that varies resistance per degree of deformation; comprising near field communication RFID tag readers, and a controller coupled to the glove to evaluate the varied resistance. A method of classifying RFID tags is also disclosed.

Abstract: A system, method, and device for enforcing access security for queries to data stored at a data source are provided. The method generates a modified query that has security enforcement functionality embedded into the modified query. The method includes (i) receiving from a user a user query for data at a data source, (ii) determining a set of permissions for the user to access data at the data source, wherein the user is associated with the user query, (iii) generating a modified query to enforce access permissions to the data at the data source, (iv) providing the modified query to the data source, and (v) obtaining the data responsive to the user query for which the user has the requisite permissions. The modified query is generated based at least in part on the user query and the set of permissions for the user.

Abstract: Described herein are methods of fabricating heat exchangers and heat source assemblies using electrochemical additive manufacturing (ECAM). A method may comprise submerging a build plate (e.g., a base and/or a heat source) and a printhead into an electrolyte and selectively activating an electrode subset of the printhead thereby electrochemically depositing a heat-exchanging portion. In the final assembly, the average coefficient of thermal expansion (CTE) of the base is closer to that of the heat source than the average CTE of the heat-exchanging portion. The combination of the heat-exchanging surfaces and the base forms openings (e.g., non-linear channels) for directing a heat transfer fluid through the heat exchanger. The openings may extend to the base and/or to the heat source for direct contact. For example, any dimension of each extension end may be less than a critical dimension, determined by adhesion, CTE mismatch, and temperature fluctuations.

Abstract: Described herein are methods and systems for additive manufacturing of parts comprising electrolytic deposits and electrophoretic deposits. Such methods and methods provide various new ways for integrating different materials into composite parts. Specifically, an additive manufacturing system comprises an electrode array with individually-addressable electrodes. Each individually-addressable electrode is coupled to a separate deposition control circuit, which selectively connects this electrode to a power supply. When forming a composite part, the electrode array can control the location of each electrolytic deposit (by controlling the current flow through each individually-addressable electrode) and each electrophoretic deposit (by controlling the electric field distribution). An electrolyte solution or an electrophoretic suspension is provided between the electrode array and deposition electrode to form corresponding deposits.

Abstract: An electrical power module includes a base plate, including an electrically isolating substrate and a first metallic layer formed on a first side of the electrically isolating substrate. The electrical power module also includes electrical connection pillars extending from the first metallic layer. The electrical power module further includes at least one encapsulant retention feature extending from the first metallic layer and including at least one surface that is angled or parallel relative to the first side of the electrically isolating substrate and faces the first side of the electrically isolating substrate. The electrical power module additionally includes at least one electrical component electrically coupled with the metallic layer of the base plate. The electrical power module further includes an encapsulant encapsulating the at least one electrical component, the metallic layer, and the at least one encapsulant retention feature and partially encapsulating the electrical connection pillars.

Abstract: A method of making an electronics package for an electrical power module includes positioning a base plate into an electrolyte solution such that a first metallic layer of the base plate directly contacts the electrolyte solution. The method also includes positioning a deposition anode array into the electrolyte solution such that a gap is established between the first metallic layer and the deposition anode array. The method further includes connecting the first metallic layer to a power source and connecting the deposition anode array to the power source. The method also includes transmitting electrical energy from the power source through the deposition anode array, through the electrolyte solution, and to the first metallic layer, such that material is deposited onto the first metallic layer and forms an electrical connection pillar, an electrical-component retention feature, and an encapsulant retention feature of the electronics package.

Abstract: Described herein are heat exchangers and heat source assemblies, which may be fabricated using electrochemical additive manufacturing (ECAM). A heat exchanger comprises a base and a heat-exchanging portion electrochemically deposited on and attached to the base and comprising heat-exchanging extensions with heat-exchanging surfaces. The combination of the heat-exchanging surfaces and the base forms openings (e.g., non-linear channels) for directing a heat transfer fluid through the heat exchanger. The openings may extend to the base for direct contact. The average CTE of the base may be closer to that of the heat source than the average CTE of the heat-exchanging portion. In some examples, the heat-exchanging portion comprises extension ends for thermal coupling to the heat source. Any dimension of each extension end may be less than a critical dimension, determined by adhesion, CTE mismatch, and temperature fluctuations.

Abstract: Described herein are heat exchangers and heat source assemblies, which may be fabricated using electrochemical additive manufacturing (ECAM). A heat exchanger comprises a support structure and a conductive seed layer having a different composition than the support structure and forming a heat-transferring surface on the heat source. The heat exchanger further comprises a heat-exchanging portion comprising heat transfer extensions. The heat transfer extensions comprise first extension ends, second extension ends, and sidewalls extending between the first extension ends and the second extension ends and forming an opening for circulating a heat transfer fluid through the heat exchanger. The first extension ends are electrochemically deposited to the heat-transferring surface and form a heat-exchanging surface. Any dimension of each extension end may be less than a critical dimension, determined by adhesion, CTE mismatch, and temperature fluctuations.

Abstract: Described herein are methods and systems for additive manufacturing of parts comprising electrolytic deposits and electrophoretic deposits. Such methods and methods provide various new ways for integrating different materials into composite parts. Specifically, an additive manufacturing system comprises an electrode array with individually-addressable electrodes. Each individually-addressable electrode is coupled to a separate deposition control circuit, which selectively connects this electrode to a power supply. When forming a composite part, the electrode array can control the location of each electrolytic deposit (by controlling the current flow through each individually-addressable electrode) and each electrophoretic deposit (by controlling the electric field distribution). An electrolyte solution or an electrophoretic suspension is provided between the electrode array and deposition electrode to form corresponding deposits.

Abstract: Conventional, manual identification and scoring of a whole slide image (WSI) to detect Cytokeratin 17 (K17) expression has limitations in terms of lower accuracy in the medium grade cases, slower turn-around time, and high inter and intra-observer variability. Each WSI can take a pathologist six to ten minutes to examine. This is because the brown color staining indicating the presence of K17 may be one of thousands or tens of thousands or other expressions present on the slide. Apparatus and methods are provided for an artificial intelligence (AI) solution that identifies and quantifies positively stained urothelial cells in WSI of urine cytology to aid the diagnosis of urinary bladder carcinoma. An illustrative AI solution may include one or computer models that are programmed to run one more machine learning (ML) models. The ML models may be trained to recognize subtle and complex patterns and features associated with specific diseases.

Abstract: An electrochemical additive manufacturing method includes positioning a cathode portion of a build plate and a deposition anode array into an electrolyte solution. The method additionally includes transmitting electrical energy from the power source through one or more deposition anodes, through the electrolyte solution, and to the cathode portion such that material is deposited onto the cathode portion. The build plate includes a thermal feature, the deposited material is thermally coupled with the thermal feature, and the deposited material forms a heat wicking feature.

Abstract: Disclosed herein are an exemplary apparatus, system, and methods (e.g., Tactical Passive RFID transponder gloves with Morphological Actuation) comprising a glove made predominately of a resistive fabric that varies resistance per degree of deformation; comprising near field communication RFID tag readers, and a controller coupled to the glove to evaluate the varied resistance. A method of classifying RFID tags is also disclosed.

Abstract: A system for detecting a gas may include a first laser having a wavelength overlapping with two or more absorption features in a spectrum of the gas, a second laser having a wavelength centered away from absorbing features in the spectrum of the gas, and at least one sensor to determine a received power of the first laser and a received power of the second laser.

Abstract: An electrochemical additive manufacturing method includes positioning a cathode portion of a build plate and a deposition anode array into an electrolyte solution. The method additionally includes transmitting electrical energy from the power source through one or more deposition anodes, through the electrolyte solution, and to the cathode portion such that material is deposited onto the cathode portion. The build plate includes a thermal feature, the deposited material is thermally coupled with the thermal feature, and the deposited material forms a heat wicking feature.

Abstract: Disclosed herein are an exemplary apparatus, system, and methods (e.g., Tactical Passive RFID transponder gloves with Morphological Actuation) comprising a glove made predominately of a resistive fabric that varies resistance per degree of deformation; comprising near field communication RFID tag readers, and a controller coupled to the glove to evaluate the varied resistance. A method of classifying RFID tags is also disclosed.

Abstract: A system for detecting a gas may include a first laser having a wavelength overlapping with two or more absorption features in a spectrum of the gas, a second laser having a wavelength centered away from absorbing features in the spectrum of the gas, and at least one sensor to determine a received power of the first laser and a received power of the second laser.

Abstract: A system for detecting a gas may include a first laser having a wavelength overlapping with two or more absorption features in a spectrum of the gas, a second laser having a wavelength centered away from absorbing features in the spectrum of the gas, and at least one sensor to determine a received power of the first laser and a received power of the second laser.

Abstract: An electrochemical additive manufacturing method includes positioning a cathode portion of a build plate and a deposition anode array into an electrolyte solution. The method additionally includes transmitting electrical energy from the power source through one or more deposition anodes, through the electrolyte solution, and to the cathode portion such that material is deposited onto the cathode portion. The build plate includes a thermal feature, the deposited material is thermally coupled with the thermal feature, and the deposited material forms a heat wicking feature.

Abstract: Described herein are methods and systems for additive manufacturing of parts comprising electrolytic deposits and electrophoretic deposits. Such methods and methods provide various new ways for integrating different materials into composite parts. Specifically, an additive manufacturing system comprises an electrode array with individually-addressable electrodes. Each individually-addressable electrode is coupled to a separate deposition control circuit, which selectively connects this electrode to a power supply. When forming a composite part, the electrode array can control the location of each electrolytic deposit (by controlling the current flow through each individually-addressable electrode) and each electrophoretic deposit (by controlling the electric field distribution). An electrolyte solution or an electrophoretic suspension is provided between the electrode array and deposition electrode to form corresponding deposits.