Abstract: The invention provides compositions and methods for using Leptospiral virulence modifying (VM) proteins or fragments or fusions thereof, as vaccines and as therapeutic agents for the treatment of cancer.

Abstract: The invention is an actuating drive for deflecting an actuating element using a solid body actuator (2) when an electrical voltage or an alternating magnetic field is applied, to cause a change in length. A housing (1) encloses the solid body actuator to define an interspace (13) in a fluid-tight manner. Furthermore, the solid body actuator includes a hollow duct (6) having one end connected to a first hollow conduit (20) passing through the housing and the other end opening into the interspace (13). The interspace is additionally connected in a fluid-tight manner to a second hollow conduit (21) passing through the housing.

Abstract: The invention relates to a test system for dynamically and/or cyclically load testing a material sample, a component, or an assembly, hereinafter referred to as sample. The test system is provided with a test frame, to which a bearing and a counter bearing are attached. At least one actuator comprising a multifunctional solid state transducer material system is connected to the counter bearing, directly or indirectly, to which, also directly or indirectly, a fastener provides firm fixation of the sample. Likewise, on the bearing side, a fastener firm fixation of the sample such that the at least one actuator is able to introduce dynamic and/or cyclical mechanical loads into the sample, which act along a load path extending lengthwise between the bearing and the counter bearing and through the sample.

Abstract: The invention ris an actuating drive for deflecting an actuating element by a solid body actuator (2) which, when an electrical voltage or an alternating magnetic field is applied, experiences a length change. A housing (1) encloses the solid body actuator to define an interspace (13) in a fluid-tight manner. Furthermore, the solid body actuator includes a hollow duct (6) having one end connected to a first hollow conduit (20) passing through the housing and the other end opening into the interspace. The interspace is additionally connected in a fluid-tight manner to a second hollow conduit (21) passing through the housing.

Abstract: The invention relates to a test system for dynamically and/or cyclically load testing a material sample, a component, or an assembly, hereinafter referred to as sample. The test system is provided with a test frame, to which a bearing and a counter bearing are attached. At least one actuator comprising a multifunctional solid state transducer material system is connected to the counter bearing, directly or indirectly, to which, also directly or indirectly, a fastener provides firm fixation of the sample. Likewise, on the bearing side, a fastener firm fixation of the sample such that the at least one actuator is able to introduce dynamic and/or cyclical mechanical loads into the sample, which act along a load path extending lengthwise between the bearing and the counter bearing and through the sample.

Abstract: The invention is a torque-limited coupling element including an input and output rotatably mounted about a common rotational axis, at least one Connection which is transferred from a first position into a second position upon exceeding a settable limit torque acting between the input and the output wherein in the first position the at least one connection connects the input and the output in a rotationally fixed manner, and in the second position, the input and the output are rotatably mounted relative to one another. A displacement body is movably mounted within a chamber filled with a magnetorheological fluid with the position of the displacement body resulting from a holding force provided by the magnetorheological fluid being under influence of a magnetic field.

Abstract: A water drain valve for an electromechanical motor vehicle power steering may include a base and a diaphragm which is configured as a movable valve element and is arranged such that it can move relative to the base between a closed position and an open position. In the closed position, the diaphragm rests against the base along an annular ring. The base may have a passage which extends from a free opening to a floor, with the diaphragm being attached centrally to the floor, the floor having at least one opening which forms a connection from the passage to the diaphragm, and the floor having at least one groove which is open towards the diaphragm and extends from the at least one opening as far as the annular ring.

Abstract: A torque-limited coupling element is described, comprising an input part and an output part, each mounted rotatably about a common rotational axis, and at least one connecting means. If a predeterminable limit torque acting between the input part and output part is exceeded, the connection means can be transferred from a first position, in which the connecting means non-rotatably connects the input part and output part to one another forming a positive engagement, into a second position, in which the input part and output part are mounted rotatably relative to one another. Furthermore, a method for torque-limited coupling and uses for such a coupling element are described.

Abstract: The invention relates to an interface for controlling (for example damping) mechanical vibrations for the automotive industry. The inventive interface comprises a base connection element, a load connection element and at least one energy converting system extending between the base connection element and the load connection element. The different energy converters of the one energy converting systems have a common preferential direction and are exposed to a preload action produced by a pretensioning element. The inventive interface also comprises a pushing force deviating element mounted between the base connection element and the load connection element which is provided with a membrane or a leaf spring disposed preferably in a perpendicular direction with respect to the preferential direction of the energy converting system. The inventive pushing force deviating element protects the energy converting systems against mechanical damage caused by an external pushing action.

Abstract: The invention is an apparatus and a method for carrying out a vibroacoustic inspection of a motor vehicle that features at least a front and a rear axle, with a test stand that is directly or indirectly connected to at least one of the two axles by means of a force flow and relative to which the motor vehicle is tied, wherein at least one vibration generator of a first type is provided along the force flow in order to generate vibrations below 50 Hz. The invention includes at least one second vibration generator of a second type, which is provided along the at least one force flow or parallel to the force flow, for generating vibrations above 30 Hz, preferably above 100 Hz, and the at least one second vibration generator is operatively connected to the motor vehicle.

Abstract: The invention is a device for dynamically load testing a sample that comprises a bearing, to which the sample can be directly or indirectly connected in a detachable manner, as well as a counter-bearing that can be effectively connected to the sample by means of at least one actuator element. The at least one actuator element introduces dynamic mechanical loads into the sample which Act along a load path that is directed between the bearing and the counter-bearing and extends through the sample. The at least one actuator element features a multifunctional solid body conversion material system that undergoes deformations due to the supply of energy, and wherein the deformations are at least one cause for the mechanical loads occurring within the sample. The device according to the invention uses at least one actuator element that may be configured in two alternative forms.

Abstract: A device and a method are described for a motor vehicle for protecting passengers during a side impact or during a collision similar to a side impact, in which an energy input acts essentially laterally on a door area of the motor vehicle, a vehicle seat being located on the side of the motor vehicle door facing away from the energy input, having at least one unit stabilizing the motor vehicle door against an energy input acting essentially laterally on the motor vehicle door, which provides at least one lateral impact girder traversing the motor vehicle door internally, which is operationally linked in case of collision to at least two support areas within stable vehicle body areas enclosing the motor vehicle door.

Abstract: Interfaces for damping mechanical vibrations are used, for example, for damping vibrations in the automotive or aerospace industry. The interfaces have a base connection element, a load connection element and a support element, with the support element being connected to the base connection element via a pretensioning device. A first energy converter system extends between engagement points on the base connection element and engagement points on the load connection element. A second energy converter system extends between engagement points on the support element and engagement points on the load connection element.

Abstract: Interfaces for damping mechanical vibrations are used, for example, for damping vibrations in the automotive or aerospace industry. The interfaces have a base connection element (10), a load connection element (28) and a support element (14), with the support element (14) being connected to the base connection element (10) via a pretensioning device (12). A first energy converter system (16, 18) extends between engagement points (20, 22) on the base connection element (10) and engagement points (24, 26) on the load connection element (28). A second energy converter system (30, 32) extends between engagement points (34, 36) on the support element (14) and engagement points (38, 40) on the load connection element (28).

Abstract: A device and a method are described for a motor vehicle for protecting passengers during a side impact or during a collision similar to a side impact, in which an energy input acts essentially laterally on a door area of the motor vehicle, a vehicle seat being located on the side of the motor vehicle door facing away from the energy input, having at least one unit stabilizing the motor vehicle door against an energy input acting essentially laterally on the motor vehicle door, which provides at least one lateral impact girder traversing the motor vehicle door internally, which is operationally linked in case of collision to at least two support areas within stable vehicle body areas enclosing the motor vehicle door.

Abstract: The invention is an apparatus and a method for carrying out a vibroacoustic inspection of a motor vehicle that features at least a front and a rear axle, with a test stand that is directly or indirectly connected to at least one of the two axles by means of a force flow and relative to which the motor vehicle is tied, wherein at least one vibration generator of a first type is provided along said force flow in order to generate vibrations below 50 Hz. The invention includes at least one second vibration generator of a second type, which provided along the at least one force flow or parallel to the force flow, for generating vibrations above 30 Hz, preferably above 100 Hz, and the at least one second vibration generator is operatively connected to the motor vehicle.

Abstract: The invention describes a device for dynamically load testing a sample that comprises a bearing, to which the sample can be directly or indirectly connected in a detachable manner, as well as a counter-bearing that can be effectively connected to the sample by means of at least one actuator element such that the at least one actuator element introduces dynamic mechanical loads into the sample which acts along a load path that is directed between the bearing and the counter-bearing and extends through the sample, wherein the at least one actuator element features a multifunctional solid body conversion material system that undergoes deformations due to the supply of energy, and wherein the deformations are the cause or at least one of the causes for the mechanical loads occurring within the sample, with the device according to the invention n being a special design of the actuator element that may be realized in two alternative forms.

Abstract: The invention relates to an interface for controlling (for example damping) mechanical vibrations for the automotive industry. The inventive interface comprises a base connection element, a load connection element and at least one energy converting system extending between the base connection element and the load connection element. The different energy converters of the one energy converting systems have a common preferential direction and are exposed to a preload action produced by a pretensioning element. The inventive interface also comprises a pushing force deviating element mounted between the base connection element and the load connection element which is provided with a membrane or a leaf spring disposed preferably in a perpendicular direction with respect to the preferential direction of the energy converting system. The inventive pushing force deviating element protects the energy converting systems against mechanical damage caused by an external pushing action.

Abstract: A device and a method are described for improving the protection of passengers in a vehicle, particularly in a motor vehicle, by reducing a force input, which is caused during a collision of the vehicle, physiologically acting on a passengers seated on a vehicle seat, using a vehicle seat positioned movably in relation to the vehicle, which may be displaced from a rest position in movement in relation to the vehicle by at least one activatable actuator, as well as an analysis and control unit, which activates the actuator for targeted vehicle seat movement as a function of sensor signals, which originate from sensors attached to the vehicle, and of predefinable reference values. The present invention is distinguished in that the at least one activatable actuator has an intelligent structure, which undergoes a shape change initiating the vehicle seat movement through activation on the basis of at least one conversion material.

Abstract: Interfaces for damping mechanical vibrations are used, for example, for damping vibrations in the automotive or aerospace industry. The interfaces have a base connection element (10), a load connection element (28) and a support element (14), with the support element (14) being connected to the base connection element (10) via a pretensioning device (12). A first energy converter system (16, 18) extends between engagement points (20, 22) on the base connection element (10) and engagement points (24, 26) on the load connection element (28). A second energy converter system (30, 32) extends between engagement points (34, 36) on the support element (14) and engagement points (38, 40) on the load connection element (28).