Abstract: A heat exchanger includes a first flow circuit structure having at least a first portion defined by a plurality of conduits and a second flow circuit structure having at least a second portion disposed at the first portion such that walls of the second portion are disposed between the conduits and are free to move relative to the conduits. Fluid flowing through the first flow circuit structure is fluidically isolated from fluid flowing through the second flow circuit structure.

Abstract: A heat exchanger includes a first fluid manifold extending along a first fluid axis from a first fluid inlet to a first fluid outlet. The first fluid manifold includes a first fluid inlet header, a first fluid outlet header, and a nested helical core section. The first fluid inlet header is disposed to fork the first fluid inlet into a plurality of first fluid branches distributed circumferentially and radially about the first fluid axis. The first fluid outlet header is disposed to combine the plurality of first fluid branches into the first fluid outlet. The nested helical core section fluidly connects the first fluid inlet header to the first fluid outlet header via a plurality of nested helical tubes, and includes radially inner and outer groups of circumferentially distributed helical tubes.

Abstract: A heat exchanger header for receiving a first fluid includes a tubular primary fluid channel oriented along a first axis and having a first cross-sectional area. A first branched region adjacent to the primary fluid channel fluidly connects to a plurality of tubular secondary fluid channels, each having a second cross-sectional area, and a second branched region adjacent to each of the secondary fluid channels fluidly connects to a plurality of tubular tertiary fluid channels, each having a third cross-sectional area. The second cross-sectional area is greater than the third cross-sectional area.

Abstract: A core arrangement for a heat exchanger includes a plurality of inlets arranged around an axis, a plurality of outlets arranged around the axis, and a plurality of bowed conduits arranged around the axis. The bowed conduits are structurally independent, connect the plurality of inlets to the plurality of outlets, bow outward from the axis between the plurality of inlets and the plurality of outlets, and provide thermal compliance to the core.

Abstract: A heat exchanger includes a first fluid manifold extending along a first fluid axis from a first fluid inlet to a first fluid outlet. The first fluid manifold comprises a inlet header, a outlet header, and a multi-helical core section. The inlet header is disposed to fork the first fluid inlet into a plurality of first fluid branches distributed laterally across a plane normal to the first fluid axis. The outlet header is disposed to combine the plurality of first fluid branches into the first fluid outlet. The multi-helical core section fluidly connects the inlet header to the outlet header via a plurality of laterally distributed helical tubes, each helical tube corresponding to one of the plurality of first fluid branches and oriented parallel to all others of the plurality of helical tubes at each axial location along the first fluid axis.

Abstract: A heat exchanger includes a first fluid manifold extending along a first fluid axis from a first fluid inlet to a first fluid outlet. The first fluid manifold includes first fluid inlet and outlet headers, and a helical core section. The inlet header is disposed to branch the first fluid inlet into a plurality of first fluid branches, and the outlet header is disposed to combine the plurality of first fluid branches into the first fluid outlet. The core section fluidly connects the inlet header to the outlet header via a plurality of helical tubes, such that each helical tube corresponds to one of the plurality of first fluid branches.

Abstract: A core arrangement for a heat exchanger includes a first core layer disposed along a first plane and having an inlet and outlet oriented along a first axis within the first plane and a first core stage disposed in fluid communication between the inlet and the outlet. The first core stage includes a first upstream fluid intersection downstream of and adjacent the inlet and having a first inlet continuation and a first bifurcation. The first core stage further includes a first downstream fluid intersection upstream of and adjacent the outlet and having a first outlet continuation and a first recombination. A plurality of first core tubes fluidly connect the first bifurcation to the first recombination. The first core layer further includes a second core stage disposed in fluid communication between the first inlet continuation and the first outlet continuation.

Abstract: A male undergarment with an expanding iris opening for maintaining the penis of a male wearer in a natural position is provided. The iris opening may be defined by a protruding boundary sleeve extending perpendicular from a crotch portion of the undergarment. The undergarment also provides a veil attached along the crotch portion, affording privacy and comfort by being movable between a concealed condition and a revealed condition.

Abstract: One variation of a method for autonomously training animals to respond to oral commands includes: prompting a user to select a training protocol; prompting the user to record a first audio clip of the user reciting a voice command associated with a target pose within the training protocol, the user affiliated with the animal; accessing a video feed recorded by an optical sensor during a first training session; in the video feed, detecting the animal within a working field; while the animal is detected in the working field, playing back the first audio clip; in the video feed, detecting a current pose of the animal; calculating a deviation between the current pose of the animal and the target pose; in response to the deviation falling within a threshold: playing an audio clip of a secondary reinforcer; and dispensing a unit of a primary reinforcer via an integrated dispenser.

Abstract: The present application relates to recombinant Clostridium difficile antigens based on a fusion protein that consists of or comprises a first amino acid sequence and a second amino acid sequence, wherein: a) the first amino acid sequence is provided by an amino acid sequence that has at least 80% sequence identity with an amino acid sequence consisting of residues 1500-1850 of a C. difficile Toxin A sequence or residues 1500-1851 of a C. difficile Toxin B sequence; and b) the second amino acid sequence is provided by an amino acid sequence that has at least 80% sequence identity with an amino acid sequence consisting of a long repeat unit located within amino acid residues 1851-2710 of a C. difficile Toxin A sequence or within amino acid residues 1852-2366 of a C. difficile Toxin B sequence; though with the proviso that the fusion protein is not a polypeptide comprising amino acid residues 543-2710 of a C.

Abstract: The present invention relates to recombinant Clostridium difficile antigens based on a fusion protein that consists of or comprises a first amino acid sequence and a second amino acid sequence, wherein: a) the first amino acid sequence is provided by an amino acid sequence that has at least 80% sequence identity with an amino acid sequence consisting of residues 500-1850 of a C. difficile Toxin A sequence or residues 1500-1851 of a C. difficile Toxin B sequence; and b) the second amino acid sequence is provided by an amino acid sequence that has at least 80% sequence identity with an amino acid sequence consisting of a long repeat unit located within amino acid residues 1851-2710 of a C. difficile Toxin A sequence or within amino acid residues 1852-2366 of a C. difficile Toxin B sequence; though with the proviso that the fusion protein is not a polypeptide comprising amino acid residues 543-2710 of a C.

Abstract: A male undergarment with an expanding iris opening for maintaining the penis of a male wearer in a natural position is provided. The iris opening may be defined by a protruding boundary sleeve extending perpendicular from a crotch portion of the undergarment. The undergarment also provides a veil attached along the crotch portion, affording privacy and comfort by being movable between a concealed condition and a revealed condition.

Abstract: An electronic module assembly has a memory module that includes a memory module and an electronic module. The memory module includes a first board having a first board first surface disposed opposite a first board second surface. The electronic module is operatively connected to the memory module. The electronic module includes a mounting plate having a mounting plate first surface that is disposed opposite a mounting plate second surface that faces towards the first board first surface. The mounting plate has a first post and a second post spaced apart from the first post.

Abstract: An electronic module assembly has a memory module that includes a memory module and an electronic module. The memory module includes a first board having a first board first surface disposed opposite a first board second surface. The electronic module is operatively connected to the memory module. The electronic module includes a mounting plate having a mounting plate first surface that is disposed opposite a mounting plate second surface that faces towards the first board first surface. The mounting plate has a first post and a second post spaced apart from the first post.

Abstract: The present invention relates to recombinant Clostridium difficile antigens based on a polypeptide, consisting of or comprising an amino acid sequence having at least 80% sequence identity with an amino acid sequence consisting of residues 1500-700 of a C. difficile Toxin A sequence or a C. difficile Toxin B sequence; though with the proviso that the polypeptide does not include one or more Repeat Unit (RU) located between amino acid residues 1851-2710 of C. difficile Toxin A and/or residues 1853-2366 of a C. difficile Toxin B protein that consists of or comprises a first amino acid sequence and a second amino acid. Also provided is the use of said antigens for the prevention/treatment/suppression of Clostridium difficile infection (CDI), together with methods for generating said antigens, methods for generating antibodies that bind to said antigens, and the use of said antibodies for the prevention/treatment/suppression of CDI.

Abstract: The present invention relates to recombinant Clostridium difficile antigens based on a polypeptide, consisting of or comprising an amino acid sequence having at least 80% sequence identity with an amino acid sequence consisting of residues 1500-700 of a C. difficile Toxin A sequence or a C. difficile Toxin B sequence; though with the proviso that the polypeptide does not include one or more Repeat Unit (RU) located between amino acid residues 1851-2710 of C. difficile Toxin A and/or residues 1853-2366 of a C. difficile Toxin B protein that consists of or comprises a first amino acid sequence and a second amino acid. Also provided is the use of said antigens for the prevention/treatment/suppression of Clostridium difficile infection (CDI), together with methods for generating said antigens, methods for generating antibodies that bind to said antigens, and the use of said antibodies for the prevention/treatment/suppression of CDI.

Abstract: The present invention relates to recombinant Clostridium difficile antigens based on a polypeptide, consisting of or comprising an amino acid sequence having at least 80% sequence identity with an amino acid sequence consisting of residues 1500-700 of a C. difficile Toxin A sequence or a C. difficile Toxin B sequence; though with the proviso that the polypeptide does not include one or more Repeat Unit (RU) located between amino acid residues 1851-2710 of C. difficile Toxin A and/or residues 1853-2366 of a C. difficile Toxin B protein that consists of or comprises a first amino acid sequence and a second amino acid. Also provided is the use of said antigens for the prevention/treatment/suppression of Clostridium difficile infection (CDI), together with methods for generating said antigens, methods for generating antibodies that bind to said antigens, and the use of said antibodies for the prevention/treatment/suppression of CDI.

Abstract: An electronics chassis for containing and supporting electronic components having different operating temperatures includes a plurality of thermally conductive walls forming an enclosure. There is a first heat dissipator in at least one of the walls having an external heat dissipator and a second heat dissipator in at least one of the walls having an external heat dissipator. There is a thermal isolator positioned in at least one of the walls to provide thermal isolation between the heat dissipators, and the thermal isolator includes a thermally insulating material.

Abstract: The present invention relates to recombinant Clostridium difficile antigens based on a polypeptide, consisting of or comprising an amino acid sequence having at least 80% sequence identity with an amino acid sequence consisting of residues 1500-700 of a C. difficile Toxin A sequence or a C. difficile Toxin B sequence; though with the proviso that the polypeptide does not include one or more Repeat Unit (RU) located between amino acid residues 1851-2710 of C. difficile Toxin A and/or residues 1853-2366 of a C. difficile Toxin B protein that consists of or comprises a first amino acid sequence and a second amino acid. Also provided is the use of said antigens for the prevention/treatment/suppression of Clostridium difficile infection (CDI), together with methods for generating said antigens, methods for generating antibodies that bind to said antigens, and the use of said antibodies for the prevention/treatment/suppression of CDI.

Abstract: A removable tool includes a toe, a clevis, and a handle. The toe is configured to be insertable into and removable from an enclosure notch of a card guided computer enclosure. The clevis is configured to be insertable into and removable from a card hook of a circuit card assembly. The handle is for receiving force for inserting or extracting an array of circuit card assembly contacts into or out of an array of motherboard contacts, respectively.