Abstract: The present invention is directed to radiolabeled 3-cyanoquinolines of the formula: and methods of synthesizing the same, wherein G1, G2 R1, R4, Z, X, and n are as defined herein. The present invention is also directed to a radiolabeled intermediate compounds of formula (VII): wherein PG, G1, R1, R4, R10, and R11 are as defined herein, and synthesis of the same.

Abstract: A method for mitigating interference from a switched-mode power supply begins by comparing a channel of interest of a plurality of channels with a switching rate of a switch-mode power supply. The method continues when the channel of interest compares unfavorably to the switching rate by adjusting the switching rate of the switch-mode power supply until the channel of interest compares favorably to the switching rate.

Abstract: A controllable oscillator includes an output oscillation adjust module operably coupled to an oscillator for producing an effective output oscillation based on an oscillation control signal. The output oscillation adjust module includes an output select block that produces the effective output oscillation from a sequence of selected taps from the plurality of taps of the oscillator. A tap adjust control generator, responsive to the oscillation control signal generates a sequence of tap adjust control signals that command the output select block to select the sequence of selected taps from the plurality of taps. The tap adjust control generator includes an integrator having an integrator output, responsive to the oscillation control signal and a modulo(x) module for producing the sequence of tap adjust control signals based on the integrator output.

Abstract: A programmable sample rate ADC includes a delta sigma modulator for producing a digital signal, and a programmable decimation filter, that includes X stages of integration, a down-sampling stage for down-sampling by a factor of N, and Y stages of differentiation. The programmable sample rate ADC produces a digital output signal at a substantially constant frequency.

Abstract: A digital clock generator includes a base clock generator for generating a base clock signal at a variable base clock frequency in response to a control signal. A digital clock controller generates a digital clock signal having a substantially constant number of digital clock cycles over a predetermined period.

Abstract: Therapeutic polymers containing a hydroxamate group that preferentially binds to active forms of a matrix metalloproteinases, thus inhibiting their enzymatic activity. The implantation of such material modifies tissue turnover and remodelling in its vicinity.

Abstract: An integrated circuit includes a radio receiver for receiving a received radio signal having a plurality of channel signals, each of the plurality of channel signals being modulated at one of a corresponding plurality of carrier frequencies. The radio receiver converts a selected one of the plurality of channel signals into a demodulated signal. An interface clock generator generates a first interface clock at a first interface clock frequency that varies based on the selected one of the plurality of channel signals. The first interface clock frequency, and integer multiples of the first clock frequency are not substantially equal to the carrier frequency of the selected one of the plurality of channel signals. A driver module drives a device interface with a device based on the first interface clock.

Abstract: A radio receiver includes a communication interface, a mixing module, an analog to digital converter, a digital gain block, and a gain setting block. The communication interface receives a continuous time radio signal. The mixing module down converts the continuous time radio signal to a continuous time analog signal. The analog to digital converter converts the continuous time analog signal to a sequence of input digital samples. The digital gain block receives the sequence of input digital samples and gain adjusts the sequence of input digital samples based upon a gain setting to produce a sequence of output digital samples. The gain setting block produces the gain setting at any time as one of a first fixed gain setting, a second fixed gain setting, and a filtered time varying gain when transitioning between the first fixed gain setting and the second fixed gain setting.

Abstract: A sample rate converter includes an up-conversion module, a linear interpolator module, and a parameter control module. The up-conversion module is operable to convert a first data rate to a second data rate of a data signal. The linear interpolator module is operable to receive the data signal at the second data rate and to produce therefrom a data signal at a desired rate based on at least one parameter. The parameter control module is operable to produce the at least one parameter based on the desired rate.

Abstract: A radio receiver front-end includes a tunable antenna interface and a low noise amplifying section. The tunable antenna interface is operably coupled to receive a wide bandwidth signal from an antenna, wherein the wide bandwidth signal includes a plurality of channel signals, and wherein the tunable antenna interface is tuned to pass a selected one of the plurality of channel signals substantially unattenuated and to attenuate remaining ones of the plurality of channel signals to produce a filtered wide bandwidth signal. The low noise amplifying section is operably coupled to amplify the filtered wide bandwidth signal to produce a filtered and amplified wide bandwidth signal.

Abstract: A system on a chip integrated circuit includes a first in-phase digital submodule and a first quadrature phase digital submodule such that the first in-phase digital submodule and the first quadrature phase digital submodule are operable to produce at least one output signal based on at least one input signal. A digital clock generator generates a first in-phase digital clock signal having a plurality of first in-phase digital clock cycles over a predetermined period and a first quadrature phase digital clock signal having a plurality of first quadrature phase digital clock cycles over the predetermined period. The plurality of first in-phase digital clock cycles are substantially interleaved with the plurality of first quadrature phase digital clock cycles over the predetermined period.

Abstract: A system on a chip integrated circuit includes an analog front end for receiving a received radio signal having a plurality of channel signals, each of the plurality of channel signals being modulated at one of a corresponding plurality of carrier frequencies, and for converting a selected one of the plurality of channel signals into a digital signal. A digital clock generator generates a digital clock signal at a digital clock frequency that varies based on the selected one of the plurality of channel signals. The digital clock frequency, and integer multiples of the digital clock frequency, are not substantially equal to the carrier frequency of the selected one of the plurality of channel signals. A digital section converts the digital signal into at least one audio signal that corresponds to the selected one of the plurality of channels, based on the digital clock signal.

Abstract: A system on a chip integrated circuit includes a first circuit module and N other circuit modules that are operable to produce at least one output signal based on at least one input signal. A reference oscillator for generating a base clock signal for the first circuit module. A clock delay generator generates N delayed clock signals at a corresponding N clock delays, wherein N is greater than or equal to 2. The N delayed clock signals are provided to the N other circuit modules.

Abstract: A system on a chip integrated circuit includes a first digital module and a second digital module such that the second digital module generates an output during the predetermined period that is based on an output of the first digital module generated during a prior predetermined period. A digital clock generator generates a base clock signal having a plurality of first digital clock cycles over a predetermined period and a second digital clock signal having a plurality of second digital clock cycles over the predetermined period.

Abstract: A system on a chip integrated circuit includes a first digital module a second digital module such that the first digital module and the second digital module are operably coupled to generate an output signal based on an input signal, based on the first digital clock signal and the second digital clock signal. A digital clock generator generates a base clock signal at a base clock frequency that varies based on a control signal and generates a first digital clock signal having a substantially constant number of first digital clock cycles over a predetermined period and for generating a second digital clock signal having a substantially constant number of second digital clock cycles over the predetermined period.

Abstract: The invention relates to the use of a thermal reversible gel, such as a copolymer composition, as a biological filler or implant. The gel has a semi-solid form at body temperature, but upon cooling to a temperature below a threshold level, the gel is liquefied and can be re-shaped, re-sized, manipulated or removed from the body. The gel may be used as a subcutaneous implant, a biological filler, joint or tissue spacer, for wrinkle filling or other cosmetic implants, as a soft-tissue replacement for reconstructive surgery, or as a barrier within the lumen of a biological structure, such as a blood vessel. The implant may be used to provide reversible birth control by providing, for example, a reversible barrier to the cervix or a reversible blockage of the lumen of the vas deferens.

Abstract: The invention relates to an ancient defense polymer having biological activity. The polymer comprises both discrete hydrophilic blocks containing cationic charge(s) and discrete hydrophobic blocks, making it amphipathic and antimicrobial in a manner analogous to natural antimicrobial peptides that form an ancient defense mechanism employed by many organisms. Such a polymer may be formed into devices designed to resist infection or bound to the surface of an apparatus to lend the biological activity to the surface of the apparatus.

Abstract: A method for managing power of a battery-powered handheld audio device by receiving an indicia of signal quality for a received continuous-time radio signal. The method compares the indicia of signal quality to a signal quality threshold. Upon a favorable comparison, enacting a first analog signal conditioning setting. Upon an unfavorable comparison, enacting a second analog signal conditioning setting. The method further provides, upon the favorable comparison, disabling a digital filtering operation, and upon the unfavorable comparison, enabling the digital filtering operation.

Abstract: A method of manufacturing a high frequency integrated circuit begins by positioning a die within a package, wherein the die includes a circuit that processes a high frequency signal and at least one bond pad operably coupled to the circuit, and wherein the package includes a plurality of bond posts, wherein at least one of the plurality of bond posts is allocated to the at least one bond pad. The method continues by bonding a first plate of a capacitor to the at least one bond pad. The method continues by bonding a second plate of the capacitor to the at one of the plurality of bond posts.

Abstract: A controlled sampling module samples an input signal from an input device and a reference signal. The controlled sampling module includes a plurality of sample capacitors, a switching network, and a switch control module for controlling the switching network. The switching network couples a first capacitor of the plurality of capacitors to the reference signal during a first phase, and to the input signal during a second phase, such that a charge on the first capacitor remaining at an end of the first phase is cancelled during the second phase.