Patents by Inventor Michael McCluskie

Michael McCluskie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADJUVANT COMPRISING A GLYCOARCHAEOL AND AN IMMUNOSTIMULANT
    Publication number: 20240082391
    Abstract: Provided is an adjuvant composition comprising a glycoarchaeol and at least one immunostimulantselected from a Toll-like receptor (TLR) agonist and a saponin. The glycoarchaeol and/orimmunostimulant may be present as a pharmaceutically acceptable salt. The adjuvant compositionmay be comprised together with an antigen in an immunogenic composition, such as a vaccine composition, which may be for use to induce an immune response in a subject. Further provided isuse of the immunogenic composition to induce an immune response in a subject, particularly animmune response that comprises both a cell-mediated response and a humoral response.
    Type: Application
    Filed: January 5, 2022
    Publication date: March 14, 2024
    Inventors: Yimei JIA, Michael MCCLUSKIE, Bassel AKACHE, Lakshmi KRISHNAN
  • Methods and compositions for inducing innate immune responses
    Publication number: 20070129320
    Abstract: The invention relates to TLR ligand formulations that comprise immune stimulating complexes and their use in inducing innate immunity.
    Type: Application
    Filed: July 18, 2005
    Publication date: June 7, 2007
    Applicants: Coley Pharmaceutical Group, Ltd., CSL Limited
    Inventors: Heather Davis, Michael McCluskie, Debra Drane
  • Methods and compositions for inducing antigen-specific immune responses
    Publication number: 20060287263
    Abstract: Vaccine compositions comprising (a) an oligonucleotide, (b) and immune stimulating complex and (c) an antigen induce a strong interferon-gamma immune response. Both oligonucleotides containing immune stimulatory motifs and oligonucleotides lacking immune stimulatory motifs contribute to an interferon-gamma response when administered with an immune stimulating complex.
    Type: Application
    Filed: July 18, 2005
    Publication date: December 21, 2006
    Inventors: Heather Davis, Michael McCluskie, Debra Drane
  • Methods and compositions for inducing innate immune responses
    Publication number: 20060019923
    Abstract: The invention relates to TLR ligand formulations that comprise immune stimulating complexes and their use in inducing innate immunity.
    Type: Application
    Filed: July 18, 2005
    Publication date: January 26, 2006
    Applicants: Coley Pharmaceutical Group, Ltd., CSL Limited
    Inventors: Heather Davis, Michael McCluskie, Debra Drane