Patents by Inventor Michael McCullagh
Michael McCullagh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11921095Abstract: A method of mass spectrometry is disclosed comprising repeatedly or continuously causing first analyte sample to be released or ejected from a first sample. A determination is made as to whether or not a quality threshold such as an intensity threshold has been met or exceeded, wherein if the quality threshold has been met or exceeded then the method further comprises repeatedly or continuously causing second analyte sample to be released or ejected from a second sample.Type: GrantFiled: October 13, 2020Date of Patent: March 5, 2024Assignee: Micromass UK LimitedInventors: Gareth Rhys Jones, Michael McCullagh, Alastair Murray Booth
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Publication number: 20230084362Abstract: Techniques and apparatus for determining atomic-level configurations of product ions are described. In some embodiments, product ion CCS information may be used to determine substructural configurations of product ions, such as isomers. For example, in one embodiment, an apparatus may include at least one memory and logic coupled to the at least one memory to: receive analytical information for a plurality of product ions, the analytical information comprising product ion collision cross-section (CCS) information, for at least one product ion of the plurality of product ions, determine a variance value of the product ion CCS information. Other embodiments are described.Type: ApplicationFiled: January 29, 2021Publication date: March 16, 2023Applicant: Waters Technologies Ireland LimitedInventors: Russell Julian Mortishire-Smith, Hans Vissers, Michael McCullagh
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Publication number: 20210109069Abstract: A method of mass spectrometry is disclosed comprising repeatedly or continuously causing first analyte sample to be released or ejected from a first sample. A determination is made as to whether or not a quality threshold such as an intensity threshold has been met or exceeded, wherein if the quality threshold has been met or exceeded then the method further comprises repeatedly or continuously causing second analyte sample to be released or ejected from a second sample.Type: ApplicationFiled: October 13, 2020Publication date: April 15, 2021Applicant: Micromass UK LimitedInventors: Gareth Rhys Jones, Michael McCullagh, Alastair Murray Booth
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Patent number: 10317363Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.Type: GrantFiled: October 23, 2017Date of Patent: June 11, 2019Assignee: MICROMASS UK LIMITEDInventors: Christopher Carver, David Eatough, Andrew Golding, Jeffrey Goshawk, Michael McCullagh
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Publication number: 20180233345Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporises a portion of the substrate. The vapour is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionised to form analyte ions which are then mass analysed.Type: ApplicationFiled: April 16, 2018Publication date: August 16, 2018Inventors: Steven Derek Pringle, Michael Raymond Morris, Stephen Smith, Michael McCullagh
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Patent number: 9947524Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analyzed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporizes a portion of the substrate. The vapor is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionized to form analyte ions which are then mass analyzed.Type: GrantFiled: June 2, 2015Date of Patent: April 17, 2018Assignee: MICROMASS UK LIMITEDInventors: Steven Derek Pringle, Michael Raymond Morris, Stephen Smith, Michael McCullagh
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Publication number: 20180045679Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.Type: ApplicationFiled: October 23, 2017Publication date: February 15, 2018Inventors: Christopher CARVER, David EATOUGH, Andrew GOLDING, Jeffrey Goshawk, Michael McCullagh
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Patent number: 9797866Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.Type: GrantFiled: April 15, 2014Date of Patent: October 24, 2017Assignee: Micromass UK LimitedInventors: Christopher Carver, David Eatough, Andrew Golding, Jeffrey Goshawk, Michael McCullagh
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Publication number: 20160054264Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.Type: ApplicationFiled: April 15, 2014Publication date: February 25, 2016Inventors: Christopher Carver, David Eatough, Andrew Golding, Jeffrey Goshawk, Michael McCullagh
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Publication number: 20150340215Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporises a portion of the substrate. The vapour is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionised to form analyte ions which are then mass analysed.Type: ApplicationFiled: June 2, 2015Publication date: November 26, 2015Inventors: Steven Derek Pringle, Michael Raymond Morris, Stephen Smith, Michael McCullagh
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Patent number: 9053914Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analyzed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporizes a portion of the substrate. The vapor is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionized to form analyte ions which are then mass analyzed.Type: GrantFiled: June 1, 2012Date of Patent: June 9, 2015Assignee: Micromass UK LimitedInventors: Steven Derek Pringle, Michael Raymond Morris, Stephen Smith, Michael McCullagh
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Publication number: 20140326865Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporises a portion of the substrate. The vapour is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionised to form analyte ions which are then mass analysed.Type: ApplicationFiled: June 1, 2012Publication date: November 6, 2014Applicant: MICROMASS UK LIMITEDInventors: Steven Derek Pringle, Michael Raymond Morris, Stephen Smith, Michael McCullagh