Abstract: Virulence factors from Burkholderia species are provided by this invention as are antibodies specifically binding the same and methods of using the virulence factors and antibodies in methods of immunizing and treating or attenuating a Burkholderia infection.

Abstract: An embodiment includes a method of self-election of a node in a subnet. The method includes receiving a first ping message. The first ping message is unicast from a second node, includes direct information related to the second node, and includes indirect information related to a third node. The method includes updating a first status of the second node in a status list stored at the first node consistent with the direct information. The method includes determining whether statuses of a threshold number of nodes have been received. Responsive to the threshold number of nodes being received, the method includes performing a local election operation. The method includes propagating a second ping message to a randomly identified additional node. The second ping message includes direct information regarding the first node and indirect information regarding at least one other node.

Abstract: An embodiment includes a method of self-election of a node in a subnet. The method includes receiving a first ping message. The first ping message is unicast from a second node, includes direct information related to the second node, and includes indirect information related to a third node. The method includes updating a first status of the second node in a status list stored at the first node consistent with the direct information. The method includes determining whether statuses of a threshold number of nodes have been received. Responsive to the threshold number of nodes being received, the method includes performing a local election operation. The method includes propagating a second ping message to a randomly identified additional node. The second ping message includes direct information regarding the first node and indirect information regarding at least one other node.

Abstract: Provided herein is a compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is hydrogen or C1-C6 alkyl; ring A is cyclohexyl or phenyl, optionally substituted; ring B is aryl or a nitrogen-containing heteroaryl, optionally substituted; ring C is phenyl substituted with hydroxyl; each L1, L2 and L3 is independently C1-C6 alkyl, —CONR2— or —CONR2—X—C1-C6 alkyl-, each optionally substituted; R2 is hydrogen or C1-C6 alkyl; and X is a bond or a 5-6 membered heterocycle containing up to 3 ring heteroatoms; and methods of use such as a method for increasing hematopoiesis, for enhancing expansion of a hematopoietic stem cell (HSC), or for inhibiting an interaction between a ?-, and/or ?-catenin protein in a cell or a subject by administering a compound of Formula (I) to the subject.

Abstract: A method for a self-electing service by a managed device is described. The method includes configuring the managed device with a service. The service is configured on at least one additional managed device in a network segment. The method also includes determining whether the managed device is selected to provide the service by negotiating with the at least one additional managed device in the network segment based on preconfigured election rules.

Abstract: Provided are: methods for treating aging or an age-related condition, symptom or disease; methods for stimulating hair growth, regrowth or pigmentation (or preventing hair loss); methods for increasing the expression of an adenosine receptor in dermal cells (in combination with hair growth); methods for treating a condition or disease of the skin or at least one symptom thereof, including cosmetic treatment (e.g., wrinkles, hyperpigmentation, redness, rosacea, dryness, cracking, loss of firmness, loss of elasticity, thinning, and loss of vibrance). The methods comprise administering a sufficient amount of a CBP/catenin (e.g., CBP/?-catenin) antagonist as disclosed, and particularly wherein administration is in an amount and manner sufficient to provide for increasing the number of asymmetric renewing divisions relative to, or at the expense of symmetric divisions in relevant somatic stem cell population. In particular aspects, the CBP/catenin (e.g.

Abstract: A method for a self-electing service by a managed device is described. The method includes configuring the managed device with a service. The service is configured on at least one additional managed device in a network segment. The method also includes determining whether the managed device is selected to provide the service by negotiating with the at least one additional managed device in the network segment based on preconfigured election rules.

Abstract: A surface well choke system has a flow chamber and a fluid switch. The flow chamber has a first flow chamber inlet with more resistance to flow to an outlet than a second flow chamber inlet has to flow to the outlet. The fluid switch has a first flow path from a fluid switch inlet to the first flow chamber inlet, a second flow path from the fluid switch inlet to the second flow chamber inlet, and a movable flow deflector upstream of the first and second flow paths. The movable flow deflector is actuable to deflect flow from the fluid switch inlet to the first flow path or the second flow path.

Abstract: Provided are: composition and methods for: treating aging or an age-related condition, symptom or disease; stimulating hair growth, regrowth or pigmentation (or preventing hair loss); for increasing adenosine receptor expression in dermal cells (in combination with hair growth); for treating a condition or disease of the skin or at least one symptom thereof, including cosmetic treatment (e.g., wrinkles, hyperpigmentation, redness, rosacea, dryness, cracking, loss of firmness, loss of elasticity, thinning, and loss of vibrancy). The methods comprise administering a sufficient amount of the disclosed CBP/catenin (e.g., CBP/(?-catenin) antagonist compositions, and particularly wherein administration is in an amount and manner sufficient to provide for increasing the number of asymmetric renewing divisions relative to, or at the expense of symmetric divisions in relevant somatic stem cell population. In particular aspects, the CBP/catenin (e.g.

Abstract: Provided are: composition and methods for: treating aging or an age-related condition, symptom or disease; stimulating hair growth, regrowth or pigmentation (or preventing hair loss); for increasing the expression of an adenosine receptor in dermal cells (in combination with hair growth); for treating a condition or disease of the skin or at least one symptom thereof, including cosmetic treatment (e.g., wrinkles, hyperpigmentation, redness, rosacea, dryness, cracking, loss of firmness, loss of elasticity, thinning, and loss of vibrance). The methods comprise administering a sufficient amount of the disclosed CBP/catenin (e.g., CBP/B-catenin) antagonist compositions, and particularly wherein administration is in an amount and manner sufficient to provide for increasing the number of asymmetric renewing divisions relative to, or at the expense of symmetric divisions in relevant somatic stem cell population. In particular aspects, the CBP/catenin (e.g.

Abstract: Multi-chip sources and related methods are disclosed. A single multi-chip lamp source can include a substrate and at least three light emitting diode (LED) chips operably configured to the substrate to form a single LED package. The LED chips can include at least three different colored LED chips. The LED chips can be configured to be actuatable either individually or together to provide selectable colored light beams. The LED chips can be positioned on the substrate such that an emitted light beam remains concentric without shifting regardless of the chip or chips emitting the light beam.

Abstract: A load carrier has a flat tray-like body that attaches to a vehicle by load bars. Multiple components may be installed on the tray body in many locations on the tray body, for containing and/or supporting cargo. One component is a cargo container that is captured and locked in one of several possible positions on the tray body. Other components are cargo posts that include one or more upending towers for supporting cargo by capturing generally vertical portions of the cargo between the towers, wherein the cargo posts may be non-pivotal, pivotal, slidable and/or adjustable. Another component is a hooked or curved depending assembly that suspends cargo from the edges of the tray body.

Abstract: Provided are: methods for treating aging or an age-related condition, symptom or disease; methods for stimulating hair growth, regrowth or pigmentation (or preventing hair loss); methods for increasing the expression of an adenosine receptor in dermal cells (in combination with hair growth); methods for treating a condition or disease of the skin or at least one symptom thereof, including cosmetic treatment (e.g., wrinkles, hyperpigmentation, redness, rosacea, dryness, cracking, loss of firmness, loss of elasticity, thinning, and loss of vibrance). The methods comprise administering a sufficient amount of a CBP/catenin (e.g., CBP/?-catenin) antagonist as disclosed, and particularly wherein administration is in an amount and manner sufficient to provide for increasing the number of asymmetric renewing divisions relative to, or at the expense of symmetric divisions in relevant somatic stem cell population. In particular aspects, the CBP/catenin (e.g.

Abstract: A load carrier has a flat tray-like body that attaches to a vehicle by load bars. Multiple components may be installed on the tray body in many locations on the tray body, for containing and/or supporting cargo. One component is a cargo container that is captured and locked in one of several possible positions on the tray body. Other components are cargo posts that include one or more upending towers for supporting cargo by capturing generally vertical portions of the cargo between the towers, wherein the cargo posts may be non-pivotal, pivotal, slidable and/or adjustable. Another component is a hooked or curved depending assembly that suspends cargo from the edges of the tray body.

Abstract: Disclosed is a load carrier made up of a flat tray like body which attaches to a vehicle by load bars. A cargo container attaches to the flat tray-like load carrier body, and is locked in one of several possible positions on the flat tray-like body. The load container may also be removed and the load carrier used without the cargo container. Devices for holding objects such as bicycles, canoes, kayaks, may also be attached to the load carrier.

Abstract: A orthopedic/spine bone mill comprising a vessel and a rotatable grinding tool to produce ground autologous and or allograft bone particles for surgical bone reconstruction use, wherein the vessel includes a wall defining a circular cylindrical chamber having a concentric axis. The vessel further includes generally concave or a cup shaped bottom wall which corresponds to the shape of the cutting blade and a lid adapted to be removably connected to the vessel. The lid includes an opening coincident with the axis. The grinding tool includes an elongated shaft extending through the opening in the Jid along the axis with a cutting blade mounted to the shaft within the chamber whereby the cutting blade can be rotated by motive device, such as a drill find in the operating room, engaging the shaft exterior of the vessel to cut bone, placed in the vessel, into said bone particles.

Abstract: The invention relates to human pluripotent cells. More specifically, the invention provides a chemically defined xeno-free culture system that allows for long term expansion of human pluripotent cells. This culture system allows for human pluripotent cell lines to be maintained in the pluripotent state for an extended time while maintaining a normal karyotype and the ability to differentiate into all three germ layers.

Abstract: Multi-chip sources and related methods are disclosed. A single multi-chip lamp source can include a substrate and at least three light emitting diode (LED) chips operably configured to the substrate to form a single LED package. The LED chips can include at least three different colored LED chips. The LED chips can be configured to be actuatable either individually or together to provide selectable colored light beams. The LED chips can be positioned on the substrate such that an emitted light beam remains concentric without shifting regardless of the chip or chips emitting the light beam.

Abstract: The device for carrying articles includes a first side portion, a second side portion and a holder unit. The first and second side portions include a means for holding the first and second side portions together. Each of the first and second side portions include an inside face and an outside face. The inside faces of the side portions are at least partially covered with either the hook or loop fabric of a hook and loop fabric fastening system. The holder unit is adapted for fitting between the side portions. At least portions of the sides of the holder unit are covered with corresponding hook or loop fabric appropriate for engaging the hook or loop fabric of the side portions. At least one of the outside faces of the side portions includes provisions for securing the carrying device to a military garment.

Abstract: Disclosed is a load carrier made up of a flat tray like body which attaches to a vehicle by load bars. A cargo container attaches to the flat tray-like load carrier body, and is locked in one of several possible positions on the flat tray-like body. The load container may also be removed and the load carrier used without the cargo container. Devices for holding objects such as bicycles, canoes, kayaks, may also be attached to the load carrier.