Abstract: The present invention relates to a monoclonal antibody capable of binding to biotin. In one embodiment the monoclonal antibody according to the invention also does not bind to a biotin moiety on a biotinylated molecule, wherein the biotin moiety is attached to the molecule via the carbon atom of the carboxyl function of the valeric acid moiety of biotin. Also disclosed is a method for generation of an antibody as disclosed herein. The monoclonal antibody according to the invention is of specific use in a method for measuring an analyte in a sample, wherein a (strept)avidin/biotin pair is used to bind a biotinylated analyte specific binding agent to a (strept)avidin coated solid phase.

Abstract: The invention provides a concept for combined dynamic range compression and guided clipping prevention for audio devices. An audio decoder for decoding an audio bitstream and a metadata bitstream related to the audio bitstream according to the concept includes an audio processing chain including a plurality of adjustment stages including a dynamic range control stage for adjusting a dynamic range of the audio output signal and a guided clipping prevention stage for preventing clipping of the audio output signal; and a metadata decoder configured to receive the metadata bitstream and to extract dynamic range control gain sequences and guided clipping prevention gain sequences from the metadata bitstream, at least a part of the dynamic range control gain sequences being supplied to the dynamic range control stage, and at least a part of the guided clipping prevention gain sequences being supplied to the guided clipping prevention stage.

Abstract: The invention provides a concept for combined dynamic range compression and guided clipping prevention for audio devices. An audio decoder for decoding an audio bitstream and a metadata bitstream related to the audio bitstream according to the concept includes an audio processing chain including a plurality of adjustment stages including a dynamic range control stage for adjusting a dynamic range of the audio output signal and a guided clipping prevention stage for preventing clipping of the audio output signal; and a metadata decoder configured to receive the metadata bitstream and to extract dynamic range control gain sequences and guided clipping prevention gain sequences from the metadata bitstream, at least a part of the dynamic range control gain sequences being supplied to the dynamic range control stage, and at least a part of the guided clipping prevention gain sequences being supplied to the guided clipping prevention stage.

Abstract: The invention provides a concept for combined dynamic range compression and guided clipping prevention for audio devices. An audio decoder for decoding an audio bitstream and a metadata bitstream related to the audio bitstream according to the concept includes an audio processing chain including a plurality of adjustment stages including a dynamic range control stage for adjusting a dynamic range of the audio output signal and a guided clipping prevention stage for preventing clipping of the audio output signal; and a metadata decoder configured to receive the metadata bitstream and to extract dynamic range control gain sequences and guided clipping prevention gain sequences from the metadata bitstream, at least a part of the dynamic range control gain sequences being supplied to the dynamic range control stage, and at least a part of the guided clipping prevention gain sequences being supplied to the guided clipping prevention stage.

Abstract: A computer-implemented method for providing a three-dimensional (3D) results data set includes: acquiring projection maps of an object under examination which are captured from various projection directions by a medical X-ray device; providing an initial projection matrix based on a static model of the X-ray device; providing a further projection matrix by applying a trained function to input data, wherein the input data is based on the initial projection matrix and the projection maps, wherein at least one parameter of the trained function is adapted based on an image quality metric and/or a consistency metric, and wherein the further projection matrix is provided as output data of the trained function; and providing the 3D results data set through reconstruction from the projection maps by the further projection matrix.

Abstract: The invention relates to a polymerisable composition comprising (i) 0 to 90% by weight of at least one inorganic filler component, (ii) 5 to 99.98% by weight of at least one urethane (alkyl) acrylate of the idealised formula I, (iii) 0.01 to 25% by weight of at least one di-, tri-, tetra- or multi-functional monomer, not being a urethane (alkyl) acrylate, (iv) 0.01 to 10% by weight of at least one initiator, of an initiator system as well as optionally of at least one stabiliser and optionally of at least one pigment, the total composition of the composition amounting to 100% by weight, as well as a polymerised composition having improved fracture toughness.

Abstract: Systems and methods for image processing that provides an output data set on the basis of an input data set relating to an examination subject.

Abstract: According to a first aspect, the invention relates to biodegradable microcapsules, comprising a core material and a shell, wherein the shell consists of at least one barrier layer and at least one stability layer, wherein the barrier layer surrounds the core material, wherein the stability layer comprises at least one biopolymer, and is arranged on the outer surface of the barrier layer, and wherein an emulsion stabilizer is arranged at the transition from barrier layer to stability layer. Furthermore, the invention relates to the use of an emulsion stabilizer to increase the amount of a stability layer that can be deposited on the surface of a barrier layer, a product containing the biodegradable microcapsules, and a method for producing the biodegradable microcapsules.

Abstract: The present invention relates to a novel monoclonal antibody that specifically binds to a conformation dependent epitope on human thymidine kinase 1 (hTK-1; SEQ ID NO:1), to methods for quantifying hTK-1 employing the antibody and to the use of the anti-hTK-1 antibody in quantifying hTK-1.

Abstract: Compositions selected from detergents and cleaning agents and cosmetic agents are described. The compositions include biodegradable microcapsules including a core material and a shell. The shell includes at least one barrier layer and one stability layer. The barrier layer surrounds the core material. The stability layer includes at least one biopolymer, and is arranged on the outer surface of the barrier layer. An emulsion stabilizer is arranged at the transition between the barrier layer and the stability layer. Use of these agents is also described.

Abstract: Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.

Abstract: A rigid PUR/PIR foam is produced from at least one polyol which is synthesized from at least one polyhydric alcohol and at least one aromatic dicarboxylic acid, wherein the polyol is at least partially produced from renewable raw materials.

Abstract: The invention provides a concept for combined dynamic range compression and guided clipping prevention for audio devices. An audio decoder for decoding an audio bitstream and a metadata bitstream related to the audio bitstream according to the concept includes an audio processing chain including a plurality of adjustment stages including a dynamic range control stage for adjusting a dynamic range of the audio output signal and a guided clipping prevention stage for preventing clipping of the audio output signal; and a metadata decoder configured to receive the metadata bitstream and to extract dynamic range control gain sequences and guided clipping prevention gain sequences from the metadata bitstream, at least a part of the dynamic range control gain sequences being supplied to the dynamic range control stage, and at least a part of the guided clipping prevention gain sequences being supplied to the guided clipping prevention stage.

Abstract: For creation of a movement-compensated image reconstruction in an x-ray based imaging method an optimal object movement trajectory is determined by application of a trained algorithm to an optimal latent vector and the movement-compensated image reconstruction is created depending on projection images, with the assumption that the object would have moved in accordance with the optimal object movement trajectory while the imaging method was being carried out.

Abstract: Provided are a method and a tool for manufacturing a coil assembly of an electric motor for a deep well vertical turbine pump with a stator assembly that has a stator bore to receive a rotor and slots radially open to the inside which are respectively separated from each other by a stator tooth and in which electrical conductors of coils of the coil assembly lie, forming distributed windings and, at one axial end of the coil assembly, a winding head. The coil assembly is manufactured by shaping and encapsulating the coils within the tool so that the winding head extends only between an inner diameter and an outer diameter that is smaller than the diameter of the stator bore in order to enable axial insertion of the coil assembly into the stator assembly leading with the winding head in which the coils are respectively wound individually, drawn into the tool as wire bundles and encapsulated within it.

Abstract: An electric motor as well as a manufacturing method for the electric motor and a manufacturing tool are provided, the electric motor being for a deep well vertical turbine pump and having a stator assembly that has a stator bore to hold a rotor and slots that are radially open to the inside, respectively separated from each other by a stator tooth, and in which electrical conductors made of round wire of coils of a coil assembly lie, with the distributed windings on one axial end of the coil assembly forming a winding head in which the coils are encapsulated. The winding head only extends between an inner diameter and an outer diameter which is smaller than the diameter of the stator bore in which the coil assembly is inserted axially into the slots of the stator assembly.

Abstract: A device for reinforcing, sealing, or damping a structural element in a motor vehicle including a support which has multiple cells, wherein each cell surrounds a cavity. Each cavity is at least partially delimited by walls in each direction, wherein each cell has an extension in length, height, and width between 5 mm and 100 mm. An outer surface of the support can be connected to the structural element by an adhesive.