Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: An information handling system may include at least one processor and a memory. The information handling system may be configured to perform a maintenance operation involving a plurality of hosts of an information handling system cluster by: determining a score for each host based on a sum of working memory sizes for all active virtual machines executing on such host plus a sum of persistent storage sizes for all virtual machines stored on such host; based on the determined scores, selecting a first host for upgrading; migrating at least a portion of all virtual machines stored on the first host from the first host to one or more other hosts; and causing the first host to perform the maintenance operation.

Abstract: Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases.

Abstract: A computer-implemented method for managing a contact center having a plurality of agents includes (a) receiving real-time data associated with each of a plurality of agents servicing incoming communications for the contact center, (b) categorizing each of the plurality of agents into a respective one of a plurality of burnout risk categories by processing the real-time data associated with each of the plurality of agents using a trained supervised machine learning model having a plurality of input features, (c) determining, based on a specification of a logical directive, an operation to be performed in relation to at least one agent in the plurality of agents, wherein the specification has at least one condition relating to the categorizing of each of the plurality of agents into the respective one of the plurality of burnout risk categories, and wherein the specification defines the operation to be performed in relation to the at least one agent in the plurality of agents upon the condition being satisfied,

Abstract: In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.

Abstract: In some implementations, a device may identify, based on spectroscopic data, a pseudo steady state end point indicating an end of a pseudo steady state associated with the blending process. The device may identify a reference block and a test block from the spectroscopic data based on the pseudo steady state end point. The device may generate a raw detection signal associated with the reference block and a raw detection signal associated with the test block. The device may generate a statistical detection signal based on the raw detection signal associated with the reference block and the raw detection signal associated with the test block. The device may determine whether the blending process has reached a steady state based on the statistical detection signal.

Abstract: Various embodiments of the present disclosure provide a strapping machine strap-feeding assembly with features that enable adjustment of the strap-feeding assembly to accommodate different strap sizes.

Abstract: A vehicle speaker mount for a speaker includes a central bracket and a plurality of elongated portions extending radially outward from the central bracket. each of the elongated portions includes a respective engagement tab at a distal end of the elongated portion with each engagement tab is configured to be releasably connectable with a base of the speaker. Furthermore, the central bracket defines at least one aperture for receiving hardware to connect the mount to a vehicle surface. The vehicle speaker mount may include a threaded ring member and a base ring for securing the vehicle surface therebetween, or a plurality of flanges extending from a base ring for providing additional mounting surfaces.

Abstract: Systems and methods are provided for an intelligent HUD. An intelligent HUD may include intelligently enabled display information. Intelligently enabled display information may include vehicle statistics, environmental statistics, warnings, instructions, and other relevant information. Intelligently enabled display information may be displayed on the HUD at a relevant time based on a triggering event. A triggering event may be operation of a vehicle contrary to law, an unsafe driving condition, or a change in information relevant to a driver. Intelligently enabled display information may be turned off after a set period of time, after a driver adjusts vehicle operation in response to a warning or instruction, and/or after a triggering event concludes.

Abstract: A vehicle speaker mount for a speaker includes a central bracket and a plurality of elongated portions extending radially outward from the central bracket. each of the elongated portions includes a respective engagement tab at a distal end of the elongated portion with each engagement tab is configured to be releasably connectable with a base of the speaker. Furthermore, the central bracket defines at least one aperture for receiving hardware to connect the mount to a vehicle surface. The vehicle speaker mount may include a threaded ring member and a base ring for securing the vehicle surface therebetween, or a plurality of flanges extending from a base ring for providing additional mounting surfaces.

Abstract: Vehicle malfunction detection systems and methods for detecting whether a lighting element of a vehicle satisfies a malfunction condition are disclosed herein. The vehicle malfunction detection system includes a detection unit detecting an operational state of the lighting element of the vehicle, and a vehicle control unit configured to place the vehicle in a driving mode, wherein, in response to determining that the operational state of the lighting element satisfies the malfunction condition, a vehicle start prevention signal is transmitted to the vehicle control unit, the vehicle start prevention signal including an instruction to prevent the vehicle from entering the driving mode.

Abstract: User alert systems, apparatus, and related methods for use with vehicles are disclosed. A disclosed alert system for a vehicle includes an intrusion detection system (IDS) operatively coupled to the vehicle. The alert system also includes a network access device (NAD) operatively coupled to the vehicle and control circuitry configured to detect, via the IDS, a malicious message transmitted through a controller area network (CAN) bus of the vehicle. The control circuitry is also configured to generate a primary alert indicative of the malicious message and transmit, via the NAD, the primary alert to a primary user device corresponding to a driver of the vehicle. The control circuitry is also configured to generate a secondary alert indicative of the malicious message and transmit, via the NAD, the secondary alert to one or more secondary user devices different from the primary user device.

Abstract: The present disclosure relates to a separating device for severing at least one strap, in particular a plastic strap, the separating device having a blade with an edge for severing the at least one strap, and it being possible for the separating device to be connected to a strap end connecting device, the strap end connecting device having an assembly which has a heating element, it being possible for the blade to be connected to that assembly of the strap end connecting device which has the heating element. In addition, the present disclosure relates to a strap end connecting device for a strapping system having a separating device of this type. In addition, the present disclosure relates to a strap end connecting device for a strapping system having a strap end connecting device of this type.

Abstract: A vehicle speaker mount for a speaker includes a central bracket and a plurality of elongated portions extending radially outward from the central bracket. each of the elongated portions includes a respective engagement tab at a distal end of the elongated portion with each engagement tab is configured to be releasably connectable with a base of the speaker. Furthermore, the central bracket defines at least one aperture for receiving hardware to connect the mount to a vehicle surface. The vehicle speaker mount may include a threaded ring member and a base ring for securing the vehicle surface therebetween, or a plurality of flanges extending from a base ring for providing additional mounting surfaces.

Abstract: Vehicle malfunction detection systems and methods for detecting whether a lighting element of a vehicle satisfies a malfunction condition are disclosed herein. The vehicle malfunction detection system includes a detection unit detecting an operational state of the lighting element of the vehicle, and a vehicle control unit configured to place the vehicle in a driving mode, wherein, in response to determining that the operational state of the lighting element satisfies the malfunction condition, a vehicle start prevention signal is transmitted to the vehicle control unit, the vehicle start prevention signal including an instruction to prevent the vehicle from entering the driving mode.

Abstract: The present disclosure relates to a strapping head of a strapping device for strapping packaged goods with a strap. The strapping head includes an advancing apparatus and tensioning apparatus having at most three rollers for transferring an advancing motion, a retracting motion, and a tensioning motion to the strap. A least one of the wheels is operatively connected to a driving apparatus to cause the at least one of the wheels to rotate about a rotational axis for the advancing, retracting, and tensioning motions. The rollers can be brought in contact with the strap in pairs on both sides of the strap in different combinations with each other.

Abstract: A method, a system, and computer readable medium for detecting interference with a navigation system are provided. The method includes detecting a global positioning system (GPS) signal via the navigation system of a vehicle, determining a signal strength of the GPS signal, determining a location of the vehicle based on the GPS signal, and determining a first attribute and a second attribute. The first attribute is determined as a function of the signal strength. The second attribute is determined as a function of the location of the vehicle. The method further includes outputting an alert indicating an interference with the navigation system when the first attribute and the second attribute are true.

Abstract: Methods, systems, devices and apparatuses for a remote control platform. The remote control platform includes a sensor. The sensor is configured to detect one or more objects within a surrounding environment of the vehicle. The remote control platform includes an electronic control unit. The electronic control unit is coupled to the sensor. The electronic control unit is configured to determine an orientation of the vehicle and a route that includes a direction of travel. The electronic control unit is configured to navigate the vehicle along the route based on the one or more objects, the direction of travel and the orientation of the vehicle.

Abstract: User alert systems, apparatus, and related methods for use with vehicles are disclosed. A disclosed alert system for a vehicle includes an intrusion detection system (IDS) operatively coupled to the vehicle. The alert system also includes a network access device (NAD) operatively coupled to the vehicle and control circuitry configured to detect, via the IDS, a malicious message transmitted through a controller area network (CAN) bus of the vehicle. The control circuitry is also configured to generate a primary alert indicative of the malicious message and transmit, via the NAD, the primary alert to a primary user device corresponding to a driver of the vehicle. The control circuitry is also configured to generate a secondary alert indicative of the malicious message and transmit, via the NAD, the secondary alert to one or more secondary user devices different from the primary user device.