Patents by Inventor Michael Millan

Michael Millan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione Mesylate salt
    Patent number: 7291740
    Abstract: Disclosed are 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione mesylate salts, or solvates thereof; processes for preparing such compounds, compositions comprising such compounds and the use of such compounds in medicine.
    Type: Grant
    Filed: August 9, 2005
    Date of Patent: November 6, 2007
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Andrew Simon Craig, Tim Chien Ting Ho, Michael Millan, Deirdre O'Keeffe
  • HYDROCHLORIDE SALT OF 5-[4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY]BENZYL]THIAZOLIDINE-2,4-DIONE
    Publication number: 20070191435
    Abstract: A novel pharmaceutical compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine
    Type: Application
    Filed: April 24, 2007
    Publication date: August 16, 2007
    Inventors: Andrew Craig, Michael Millan
  • SODIUM SALTS OF 5-[4-[2-(N-METHYL-N-(2-PYRIDYL)AMINO)ETHOXY]BENZYL]THIAZOLIDINE-2,4-DIONE
    Publication number: 20070185167
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscopic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: April 23, 2007
    Publication date: August 9, 2007
    Inventors: Andrew CRAIG, Michael Millan
  • Inclusion complexes of rosiglitazone
    Publication number: 20060094691
    Abstract: A host-guest complex, wherein the host is a cyclodextrin or a mixture of cyclodextrins (the Cyclodextrin) and the guest is 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione, (Compound (I)) or a pharmaceutically acceptable derivative thereof or a mixture thereof; a process for the preparation of said complex, a pharmaceutical composition comprising such complex and the use of such complex in medicine.
    Type: Application
    Filed: May 23, 2003
    Publication date: May 4, 2006
    Inventors: Andrew Craig, David Crowe, Michael Millan
  • Amorphous pharmaceutical compositions
    Publication number: 20060083784
    Abstract: The present invention is directed to use of electrospinning, i.e. the process of making polymer nanofibers from either a solution or melt under electrical forces, to prepare stable, solid dispersions of amorphous drugs in polymer nanofibers. The present invention is also directed to the process of making solid dispersions of amorphous forms and compositions of rosiglitazone and its pharmaceutically acceptable salts.
    Type: Application
    Filed: February 24, 2005
    Publication date: April 20, 2006
    Inventors: Francis Ignatious, Linghong Sun, Andrew Craig, David Crowe, Tim Ho, Michael Millan
  • 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione Mesylate salt
    Publication number: 20060040993
    Abstract: Disclosed are 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione mesylate salts, or solvates thereof; processes for preparing such compounds, compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: August 9, 2005
    Publication date: February 23, 2006
    Inventors: Andrew Craig, Tim Ho, Michael Millan, Deirdre O'Keeffe
  • Sodium salts of 5-'4-'2-(N-methyl-N-(2-pyridyl) amino) ethoxy!benzyl!thiazolidine -2, 4-dione
    Publication number: 20060004058
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscapic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: August 17, 2005
    Publication date: January 5, 2006
    Inventors: Andrew Craig, Michael Millan
  • Hydrochloride salt of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazo-lidine-2,4-dione
    Publication number: 20050282867
    Abstract: A novel pharmaceutical compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: August 4, 2005
    Publication date: December 22, 2005
    Inventors: Andrew Craig, Michael Millan
  • Sodium salts of 5-'4-'2-(N-methyl-N-(2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione
    Publication number: 20050277679
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscapic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: May 19, 2004
    Publication date: December 15, 2005
    Inventors: Andrew Craig, Michael Millan
  • Rosiglitazone edisylates and their use as antidiabetics
    Publication number: 20050107440
    Abstract: A salt of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione and 1,2-ethanedisulfonicacid, a process for the preparation of the salt, pharmaceutical compositions comprising the salt and the use of the salt in medicine.
    Type: Application
    Filed: November 21, 2002
    Publication date: May 19, 2005
    Inventors: Tim Chien Ho, Michael Millan
  • Crystalline complexes of fluticasone-2-furoate
    Publication number: 20050043284
    Abstract: There is provided a crystalline complex comprising a compound of formula (I) in which the crystal lattice is stabilised by the presence of a guest molecule, characterised in that the crystalline complex is of space group P212121 having unit cell dimensions of about 12.5±1.0 ?, 15±1.0 ?, and 16.2±1.0 ? when determined at either 120 K or 150 K.
    Type: Application
    Filed: February 4, 2003
    Publication date: February 24, 2005
    Inventors: Keith Biggadike, Steven Coote, Andrew Craig, David Crowe, Victor Jacewicz, Michael Millan, Rosalyn Nice, Brian Noga, John Seager, Andrew Theophilus
  • Sodium salts of 5-'4-'2-(N-methyl-N-(2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione
    Publication number: 20040214866
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscapic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: May 18, 2004
    Publication date: October 28, 2004
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Andrew Simon Craig, Michael Millan
  • 5'-4-'2-(n-methyl-n-(2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione mesylate salt
    Publication number: 20040082620
    Abstract: Disclosed are 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione mesylate salts, or solvates thereof; processes for preparing such compounds, compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: December 4, 2003
    Publication date: April 29, 2004
    Inventors: Andrew Simon Craig, Tim Chien Ting Ho, Michael Millan, Deirdre O'Keeffe
  • Thiazolidinedione derivative and its use as antidiabetic
    Publication number: 20040038968
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione potassium salt or a pharmaceutically acceptable solvate thereof, a pharmaceutical composition containing such a compound and the use of such a compound in medicine, particularly in the treatment of diabetes mellitus.
    Type: Application
    Filed: July 15, 2003
    Publication date: February 26, 2004
    Inventor: Michael Millan
  • Hydrochloride salt of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]thiazolidine-2,4-dione
    Publication number: 20040034066
    Abstract: A novel pharmaceutical compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride, a process for preparing such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine
    Type: Application
    Filed: July 16, 2003
    Publication date: February 19, 2004
    Inventors: Andrew Simon Craig, Michael Millan
  • Sodium salts of 5-[4-]2-(n-methyl-N-(2-pyridyl) ethoxy]benzyl]thiazolidine-2,4-dione
    Publication number: 20040014752
    Abstract: A compound 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione sodium salt, or a pharmaceutically acceptable solvate thereof, characterised in that the sodium salt is non-hygroscopic or slightly hygroscapic; a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 22, 2004
    Inventors: Andrew Simon Craig, Michael Millan