Abstract: The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of a Retroviridae infection, including an HIV infection.

Abstract: Described herein are compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies. In particular embodiments, the disclosure provides fully human anti-ST2 antibodies and deriviatives and variants thereof. Further provided are nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives. Also, provided are methods of making and using such antibodies including methods of treating and preventing autoimmune and inflammatory disorders.

Abstract: The present invention relates to antibodies that specifically bind to one or more of IL-4, IL-13, IL-33, TSLP, and p40. The present invention further relates to antibodies that bind to one of IL-4, IL-13, IL-33, or TSLP. The invention further relates to multispecific antibodies that specifically bind to IL-4 and IL-13, and at least one other target. The present invention relates to multispecific antibodies that bind IL-4, IL-13, and one of IL-33, TSLP, or p40. The present invention also pertains to related molecules, e.g. nucleic acids which encode such antibodies or multispecific antibodies, compositions, and related methods, e.g., methods for producing and purifying such antibodies and multispecific antibodies, and their use in diagnostics and therapeutics.

Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.

Abstract: The present invention provides a composition comprising a GLP-1 receptor agonist and a glucagon receptor agonist and an application of the composition. More specifically, the present invention provides a pharmaceutical composition comprising a pharmaceutically effective amount of the GLP-1 receptor agonist and the glucagon receptor agonist, wherein the GLP-1 receptor agonist and the glucagon receptor agonist independently form a conjugate with a hydrophilic polymer, or the GLP-1 receptor agonist and the glucagon receptor agonist jointly form a conjugate with the hydrophilic polymer.

Abstract: A video display system may include a video display including a plurality of video display modules, a truss supporting the video display, a lower portion of the truss anchored to a floor, and the lower portion may be coupled to the video display at a position between the terminal sides of the video display and may extend approximately one-third of the length of the video display. The video display system may include a upper portion of the truss above the lower portion and anchored to a ceiling, wherein the upper portion may be coupled to the video display at a position between the terminal sides of the video display and may extend approximately one-third of the length of the video display.

Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.

Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.

Abstract: The present invention provides a composition comprising a GLP-1 receptor agonist and a glucagon receptor agonist and an application of the composition. More specifically, the present invention provides a pharmaceutical composition comprising a pharmaceutically effective amount of the GLP-1 receptor agonist and the glucagon receptor agonist, wherein the GLP-1 receptor agonist and the glucagon receptor agonist independently form a conjugate with a hydrophilic polymer, or the GLP-1 receptor agonist and the glucagon receptor agonist jointly form a conjugate with the hydrophilic polymer.

Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.

Abstract: The present invention relates to containers for holding liquid samples. The containers may be useful for mixing a liquid sample or lysing cells in a liquid sample. The invention also relates to methods of using the containers of the invention.

Abstract: Multi-armed functional polyethylene glycol polymers with active terminal groups may be used in conjugation with small molecule pharmaceuticals, proteins and peptides to enhance half-life and bioavailability of the drug and improve solubility, stability and immunological competence.

Abstract: The invention relates to a driver circuit for driving a word line of a memory. The driver circuit comprises a driver unit for deactivating the word line after an access to a memory cell, a discharging means for discharging the word line, and a signal generator that generates two control signals. A first signal triggers the driver unit to deactivate the word line and triggers the discharging means to discharge the word line. A second signal triggers the discharging mean to stop discharging the word line.

Abstract: A stretcher comprises a patient support area supported by front legs and rear legs. The front legs and rear legs are coupled by a gear mechanism, and an actuation device coupled to the gear mechanism effects retraction or extension of the stretcher in a smooth and continuous motion. The actuation device is operable to lock the gear mechanism to position the stretcher at any desired height between fully extended and fully retracted.

Abstract: A stretcher comprises a patient support area supported by front legs and rear legs. The front legs and rear legs are coupled by a gear mechanism, and an actuation device coupled to the gear mechanism effects retraction or extension of the stretcher in a smooth and continuous motion. The actuation device is operable to lock the gear mechanism to position the stretcher at any desired height between fully extended and fully retracted.

Abstract: A light guide module (10) for use in a flat panel display (21) comprises a light guide pipe (20) having a light emitting surface (21), and a light incident surface (25) orthogonal to the light emitting surface. A light diffusion arrangement (30) is deployed over the light emitting surface and includes organic scattering balls (31) homogenously mixed within a bonding agent (33). At least a light source (60) is arranged adjacent the light incident surface to project light beams into the light guide module.