Abstract: The present invention relates to new pharmaceutical agents, and to their use in the treatment of proliferative diseases, such as cancer (in particular, brain cancer).

Abstract: An electric submersible pump (ESP) power cable. The ESP power cable has a first plurality of electric conductors encased in a first protective armor wherein a first void area is defined between the first plurality of electric conductors and the first protective armor, has a second plurality of electric conductors encased in a second protective armor wherein a second void area is defined between the second plurality of electric conductors and the second protective armor and wherein each one of the second plurality of electric conductors is spliced to a corresponding one of the first plurality of electric conductors, has a first filler positioned at least partially in the first void area, and comprises a second filler positioned at least partially in the second void area.

Abstract: A centrifugal electric submersible pump (ESP). The centrifugal ESP comprises a rotatable shaft, a series of impellers stacked on the rotatable shaft, each impeller comprising a hub secured to the rotatable shaft by a key, the series of impellers comprising an uppermost impeller and a lowermost impeller, a flanged sleeve keyed to the rotatable shaft below the lowermost impeller, and a seal disposed between the lowermost impeller and the flanged sleeve.

Abstract: An electric submersible pump (ESP) power cable. The ESP power cable comprises a first plurality of electric conductors encased in a first protective armor wherein a first void area is defined between the first plurality of electric conductors and the first protective armor, comprises a second plurality of electric conductors encased in a second protective armor wherein a second void area is defined between the second plurality of electric conductors and the second protective armor and wherein each one of the second plurality of electric conductors is spliced to a corresponding one of the first plurality of electric conductors, comprises a first filler positioned at least partially in the first void area, and comprises a second filler positioned at least partially in the second void area.

Abstract: The invention relates generally to an Internet of Things (IoT) enabled wireless sensor system using attached and/or embedded passive electromagnetic sensors (PES) with distribution hardware. One embodiment of this invention includes a wireless sensor system, which permits process control and predictive maintenance on a utility's electrical transmission and distribution grid. Another embodiment includes a wireless sensor system, which permits process control and predictive maintenance of liquid or gas through a pipeline. Another embodiment includes a wireless sensor system, which permits measurement of breathable air pollutants. Furthermore, a method of manufacturing a protective passive electromagnetic sensor pod and passive electromagnetic sensor equipped distribution hardware components is provided.

Abstract: The invention relates generally to an Internet of Things (IoT) enabled wireless sensor system using attached and/or embedded passive electromagnetic sensors (PES) with distribution hardware. One embodiment of this invention includes a wireless sensor system, which permits process control and predictive maintenance on a utility's electrical transmission and distribution grid. Another embodiment includes a wireless sensor system, which permits process control and predictive maintenance of liquid or gas through a pipeline. Another embodiment includes a wireless sensor system, which permits measurement of breathable air pollutants. Furthermore, a method of manufacturing a protective passive electromagnetic sensor pod and passive electromagnetic sensor equipped distribution hardware components is provided.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: A centrifugal electric submersible pump (ESP). The centrifugal ESP comprises a rotatable shaft, a series of impellers stacked on the rotatable shaft, each impeller comprising a hub secured to the rotatable shaft by a key, the series of impellers comprising an uppermost impeller and a lowermost impeller, a flanged sleeve keyed to the rotatable shaft below the lowermost impeller, and a seal disposed between the lowermost impeller and the flanged sleeve.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: Systems and methods are disclosed for improving the speed and accuracy of terrestrial tracking with more than one receiver. Furthermore, terrestrial tracking of more than one receiver can be improved in areas where terrestrial tracking has been difficult to accomplish with acceptable accuracy, such as in rural areas where buildings can reflect satellite, and other, signals. For example, fast and precise position estimation in a short delay multipath environment can be solved by simultaneously estimating the position of multiple receivers using receiver to receiver distance ranges.

Abstract: Among other things, embodiments of the present disclosure may be used to help train speech recognizers for improving generalized voice experience quality in a chat bot system. In some embodiments, the system provides users with games to play to increase user engagement with the chat bot system.

Abstract: Various technologies pertaining to computer-executable instruction sequence forensics are described herein. In a general embodiment, an application development framework supports a function library that includes a plurality of recording functions. Calls to these functions are inserted into source code or bytecode of the computer-executable instruction sequence. The source code is then compiled, resulting in formation of instrumented machine code of the computer-executable instruction sequence. Alternately, the runtime environment interprets instrumented bytecode for the instruction sequence. A processor executes the machine code, and the called functions cause the processor to generate forensic data pertaining to portions of the computer-executable instruction sequence that correspond to locations in the source code where the calls were inserted. An execution instance of the computer-executable instruction sequence is visualized based upon the forensic data.

Abstract: A method and system for networking a plurality of appliances. The method and system include providing an appliance on a network, controlling operation of the appliance with a microcontroller, storing on a memory coupled with the microcontroller, computer executable instructions for operating the appliance, sensing the operation of the appliance, displaying information regarding the operation of the appliance, and communicating the operational data on a network. Network connectivity includes communication directly with a network, and with another appliance. A host system is connected to the network and adapted to receive the usage data and to transmit data to the appliance to influence operation of the appliance.

Abstract: Systems and methods are disclosed for improving the speed and accuracy of terrestrial tracking with more than one receiver. Furthermore, terrestrial tracking of more than one receiver can be improved in areas where terrestrial tracking has been difficult to accomplish with acceptable accuracy, such as in rural areas where buildings can reflect satellite, and other, signals. For example, fast and precise position estimation in a short delay multipath environment can be solved by simultaneously estimating the position of multiple receivers using receiver to receiver distance ranges.

Abstract: A method and system for networking a plurality of appliances. The method and system include providing an appliance on a network, controlling operation of the appliance with a microcontroller, storing on a memory coupled with the microcontroller, computer executable instructions for operating the appliance, sensing the operation of the appliance, displaying information regarding the operation of the appliance, and communicating the operational data on a network. Network connectivity includes communication directly with a network, and with another appliance. A host system is connected to the network and adapted to receive the usage data and to transmit data to the appliance to influence operation of the appliance.

Abstract: Medical devices and methods for manufacturing medical devices. An example manufacturing method includes providing a metallic tubular member having a inner surface with a metal oxide layer disposed thereon, mechanically scoring and/or removing a portion of the metal oxide layer to create a bonding zone along the inner surface, and soldering an additional metallic structural element to the bonding zone.

Abstract: An appliance is provided for connecting the water-tight cap of an endoscope using the distal end of the appliance to connect the water-tight cap over a venting pin connector to the proximal body of the endoscope or bronchoscope over the “S” connector by the proximal end of the appliance. In one version of the invention, one end of the appliance is connected to the “S” connector of the proximal body of the endoscope, as described in detail herein. In another version of the invention, one end of the appliance is wrapped around the proximal body of the endoscope, as described in detail herein. The invention also includes methods of operating the appliance.

Abstract: An automated Triage Administrator system that links data for prescription requests, prescription refill requests, medical history requests and a patient's prescription history in a data base. The system allows pharmacies and physicians access to the desired medical information by fax or internet protocols. The system also provides all newly issued and current prescriptions to be joined into one “Super Prescription” for convenient distribution.

Abstract: Medical devices and methods for manufacturing medical devices. An example manufacturing method includes providing a metallic tubular member having a inner surface with a metal oxide layer disposed thereon, mechanically scoring and/or removing a portion of the metal oxide layer to create a bonding zone along the inner surface, and soldering an additional metallic structural element to the bonding zone.