Patents by Inventor MICHAEL N. STARNBACH

MICHAEL N. STARNBACH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPARTICLE-BASED COMPOSITIONS
    Publication number: 20200215179
    Abstract: Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.
    Type: Application
    Filed: November 11, 2019
    Publication date: July 9, 2020
    Inventors: Georg Stary, Aleksandar Filip Radovic-Moreno, Pamela A. Basto, Michael N. Starnbach, Robert S. Langer, Omid C. Farokhzad, Ulrich Von Andrian
  • Compositions for and methods of identifying antigens
    Patent number: 10662423
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: May 26, 2020
    Assignee: President and Fellows of Harvard College
    Inventors: Darren E. Higgins, Michael N. Starnbach, Todd Gierahn, Nadia R. Roan
  • Nanoparticle-based compositions
    Patent number: 10485861
    Abstract: Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 26, 2019
    Assignees: President and Fellows of Harvard College, Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Georg Stary, Aleksandar Filip Radovic-Moreno, Pamela A. Basto, Michael N. Starnbach, Robert S. Langer, Omid C. Farokhzad, Ulrich Von Andrian
  • COMPOSITIONS FOR AND METHODS OF IDENTIFYING ANTIGENS
    Publication number: 20190032041
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Application
    Filed: February 12, 2018
    Publication date: January 31, 2019
    Inventors: Darren E. HIGGINS, Michael N. STARNBACH, Todd GIERAHN, Nadia R. ROAN
  • Compositions for and methods of identifying antigens
    Patent number: 9920314
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: March 20, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Darren E. Higgins, Michael N. Starnbach, Todd Gierahn, Nadia R. Roan
  • COMPOSITIONS FOR AND METHODS OF IDENTIFYING ANTIGENS
    Publication number: 20160090589
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Application
    Filed: May 6, 2015
    Publication date: March 31, 2016
    Inventors: Darren E. HIGGINS, Michael N. Starnbach, Todd Gierahn, Nadia R. Roan
  • NANOPARTICLE-BASED COMPOSITIONS
    Publication number: 20160008451
    Abstract: Provided herein are new compositions including an inactivated pathogen and one or more adjuvant-loaded polymeric nanoparticles, wherein the adjuvant-loaded nanoparticles are bound to the inactivated pathogen. These compositions are useful for preventing and/or treating diseases caused by the specific pathogens, especially when administered to a subject's mucosal membranes.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 14, 2016
    Inventors: Georg STARY, Aleksandar Filip RADOVIC-MORENO, Pamela A. BASTO, Michael N. STARNBACH, Robert S. LANGER, Omid C. FAROKHZAD, Ulrich Von ANDRIAN
  • Compositions for and methods of identifying antigens
    Patent number: 9051564
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: June 9, 2015
    Assignee: President and Fellows of Harvard College
    Inventors: Darren E. Higgins, Michael N. Starnbach, Todd Gierahn, Nadia R. Roan
  • Compositions for and Methods of Identifying Antigens
    Publication number: 20110076288
    Abstract: Replicable libraries having discrete members in defined locations for screening for antigens to a pathogenic organism are provided. Also provided are methods for using such libraries as well as a specific antigen, CT788, which induces T-cell activation during a Chlamydia infection.
    Type: Application
    Filed: February 21, 2007
    Publication date: March 31, 2011
    Applicant: President and Fellows of Harvard College
    Inventors: Darren E. Higgins, Michael N. Starnbach, Todd Gierahn, Nadia R. Roan
  • CHLAMYDIA ANTIGENS
    Publication number: 20100260791
    Abstract: Chlamydia antigens (e.g., polypeptides, polypeptide fragments, and fusion proteins) are provided. Also provided are vaccines and pharmaceutical compositions for treating or preventing a bacterial infection, such as Chlamydia, in a subject.
    Type: Application
    Filed: August 1, 2008
    Publication date: October 14, 2010
    Applicant: President and Fellows of Harvard
    Inventors: Darren E. Higgins, Todd Gierahn, Michael N. Starnbach, Nadia R. Roan
  • USE OF TOXIN PEPTIDES AND/OR AFFINITY HANDLES FOR DELIVERING COMPOUNDS INTO CELLS
    Publication number: 20030202989
    Abstract: A method and compositions for delivering a compound to the cytoplasm of a cell are disclosed. The compound to be delivered may be an antigenic compound, may be linked to a polycationic affinity handle, or both. In one of the methods disclosed, the B moiety of a toxin, such as the anthrax PA polypeptide, is also provided to enhance delivery of the compound to the cytoplasm of the cell.
    Type: Application
    Filed: April 8, 1999
    Publication date: October 30, 2003
    Inventors: R. JOHN COLLIER, STEVEN R. BLANKE, JILL C. MILNE, ERICKA L. BENSON, JIMMY D. BALLARD, MICHAEL N. STARNBACH