Abstract: A system for identifying efficacious markers comprises memory storing collected multimodal digital markers from a first cohort experiencing a sign onset and a second cohort experiencing a non-sign onset. The system further comprises selection logic that identifies a subset of markers that best capture differences between the sign and non-sign onsets. The system further comprises responsiveness logic that determines a responsiveness parameter that specifies a rate of change in the subset. The system further comprises time to detect change logic that determines a time parameter that specifies a time required to detect change in the subset. The system further comprises sample size logic that determines how the responsiveness parameter and the time parameter change depending on sample size. The system further comprises sensitivity logic that determines a sensitivity parameter that specifies whether the subset detects condition deterioration during intervals when no changes are reported in an external standard.

Abstract: A computer-implemented method of generating interpretable, composite marker indexes that are discriminative and noise-robust is provided. The method comprises storing remotely collected multimodal digital markers from a first cohort and a second cohort. The method further comprises grouping multicollinear features in the multimodal digital markers into clusters, and then selecting representative features for the clusters for multiple classification tasks that require discrimination between the first cohort and the second cohort. The method further comprises linearly combining the representative features into an interpretable, composite marker index such that relative contributions of each of the representative features to the interpretable, composite marker index are known.

Abstract: A computer-generated dialog session is customized for a user having a pathology characterized at least in part by a speech pathology. The user's speech is analyzed for spans of speech in which the starts and ends of the spans satisfy predetermined thresholds of time. Customization occurs by altering at least one of the following configurable parameters: (a) a threshold minimum signal strength of speech (dB) to consider as the start of the span of speech; (b) an adjustment factor by which signal strengths of background noise increases between consecutive spans of speech; (c) a threshold between signal strength during the span of speech and signal strength during the span of non-speech; (d) a start speech time threshold; and (e) an end speech time threshold.

Abstract: A system for remotely determining the potential presence of depression in a user. The system includes a virtual agent that administers one or more tasks to the user. The user performs the tasks and the performance is captured by a camera. The captured audiovisual data is sent to a server that derives objective metrics which are then applied to a classifying algorithm. If certain metrics meet certain thresholds, the system determines that the user is exhibiting depression symptoms. In embodiments, the system can further determine whether a user has been taking depression medication.

Abstract: A system for administering performance tests to patients remotely has a server that can execute one or more performance tests, presented to the patient via a virtual agent running on the patient's computing device. The performance tests ask the patient to perform a task and then the patient's computing device captures the performance of the task such that the server can analyze the results and determine whether the patient suffers from a condition. The system is capable of adapting based on how a patient performs the tests, whether additional tests are needed or due to technical difficulties.

Abstract: A snap-action cage for a tapered roller bearing is configured as a window cage with a plurality of windows for receiving tapered rollers, with a first cage portion having a plurality of first web portions. The first web portions in each case define run-on surfaces for the tapered rollers. A second cage portion has a plurality of second web portions that are connectable and/or are connected to the first web portions via a snap-action connection, in order to form in each case one web. The second web portions are configured spaced apart in the circulating direction from and/or without contact with the run-on surfaces. The hook receptacle has a fork hook with a hook groove which is configured in between, and the snap-action hook snaps into the fork hook, and a guide portion is held in the hook groove in a positively locking manner in the circulating direction.

Abstract: The disclosure relates to a switching element comprising an external part and an internal part, which is axially displaceable in a bore of the external part. At least one radially displaceable locking element is disposed within at least one receptacle of the internal part and includes a flattened portion on a radially outwardly directed end. At least one recess of the external part can be acted upon by a control pressure and the at least one locking element can thereby be radially displaced from the locking position into a release position. At least in a respective locking position, a chamber delimited by the at least one locking element is spatially separated from the at least one recess of the external part by a respective locking section. At least one bypass is designed, which indirectly fluidly connects the at least one recess of the external part and a respective chamber.

Abstract: Disclosed are oral care compositions comprising a thickening silica and a fluoride ion source, wherein fluoride is absorbed on the thickening silica and wherein the pH of the composition is below 5.5, as well as to methods of using these compositions. The thickening silica may have a particle size distribution (D95) less than or equal to 7 ?m and a BET surface area of greater than or equal to 150 m2/g.

Abstract: The disclosure relates to a switching element comprising an external part and an internal part, which is axially displaceable in a bore of the external part. At least one radially displaceable locking element is disposed within at least one receptacle of the internal part and includes a flattened portion on a radially outwardly directed end. At least one recess of the external part can be acted upon by a control pressure and the at least one locking element can thereby be radially displaced from the locking position into a release position. At least in a respective locking position, a chamber delimited by the at least one locking element is spatially separated from the at least one recess of the external part by a respective locking section. At least one bypass is designed, which indirectly fluidly connects the at least one recess of the external part and a respective chamber.

Abstract: A system and method for remote monitoring of patient motor functions includes a computing device that uses captured image data depicting a patient's body part and, based on movement information, detects whether a condition may exist that is affecting motor functions. The body part can be a hand that is tracked as the user performs a tapping exercise. The body part can also include the patient's face during speech and also without speech.

Abstract: A virtual agent instructs a responding person to perform specific verbal exercises. Audio and image inputs from the responding person's performance of the exercises are used to identify speech, video, cognitive, and/or respiratory biomarkers, which are then used to evaluate speech motor function and/or neurological health. Contemplated exercises include test aspects of oral motor proficiency, sustained phonation, diadochokinesis, reading speech, spontaneous speech, spirometry, picture description, and emotion elicitation. Metrics from evaluation of the responding person's performance are advantageously produced automatically, and are presented in spreadsheet format.

Abstract: A refrigeration appliance device, in particular a household refrigeration appliance device, which achieves a high level of efficiency, includes an inner compartment, which forms a storage space for articles and which is made up at least of a first inner-compartment part and at least of a second inner-compartment part, which is adjacent to the first inner-compartment part and is formed separately from the first inner-compartment part. At least one prefabricated, in particular at least substantially panel-shaped, thermal insulation element, is fastened on at least one side of the inner compartment directed away from the storage space. A refrigeration appliance and/or freezer having the refrigeration appliance device, a modular system for manufacturing the refrigeration appliance device, and a method for producing the refrigeration appliance device, are also provided.

Abstract: A computer-generated dialog session is customized for a user having a pathology characterized at least in part by a speech pathology. The user's speech is analyzed for spans of speech in which the starts and ends of the spans satisfy predetermined thresholds of time. Customization occurs by altering at least one of the following configurable parameters: (a) a threshold minimum signal strength of speech (dB) to consider as the start of the span of speech; (b) an adjustment factor by which signal strengths of background noise increases between consecutive spans of speech; (c) a threshold between signal strength during the span of speech and signal strength during the span of non-speech; (d) a start speech time threshold; and (e) an end speech time threshold.

Abstract: An armrest console includes an armrest, a fixed gear coupled to a top of a storage compartment in the armrest console, an elevating gear coupled to the armrest; a dampener gear engaged with the elevating gear and the fixed gear, and a gear connector to receive the elevating gear and the dampener gear. When the armrest is rotated about an axis of the elevating gear in a counterclockwise direction to open, the elevating gear is rotated in the counterclockwise direction and the dampener gear is rotated in a clockwise direction and both the elevating gear and the dampener gear are rotated about an axis of the fixed gear, and wherein the elevating gear and the dampener gear are moved up at a height direction when the armrest is rotated to open.

Abstract: A virtual agent converses with a patient or other person to assess one or more psychological or other medical conditions of the other person. The virtual agent uses both semantic and affect content from the person to branch the conversation, and to assess a psychological or other condition of the person. The virtual agent can have artificial intelligence functionalities or can utilize a separate artificial intelligence functionality. A communication agent can be utilized to monitor a telecommunication session with the person, and if appropriate, modify relative bandwidth utilization between the audio and image inputs. The virtual agent/artificial intelligence agent can simultaneously assist multiple virtual agents, who are each conversing with a responding person assessing their psychological or other medical condition(s), in parallel. The contemplated virtual agents can be especially useful in assessing disorder severity in multiple neurological and mental disorders.

Abstract: Disclosed are oral care compositions comprising a thickening silica and a fluoride ion source, wherein fluoride is absorbed on the thickening silica and wherein the pH of the composition is below 5.5, as well as to methods of using these compositions. The thickening silica may have a particle size distribution (D95) less than or equal to 7 ?m and a BET surface area of greater than or equal to 150 m2/g.

Abstract: Inertial lock systems for push-push latch style vehicle drawers or storage bins including an inertia lock to maintain a drawer in a closed position under a g-force. A shaft is rotatably mounted on a drawer housing; an inertia member is mounted on the shaft; and a confining member is mounted on the shaft and disposed opposite to the inertia member. The confining member is configured to move to a position to restrict movement of a rotating latch of the drawer when a g-forced applied to the drawer exceeds a predetermined level.

Abstract: An armrest console includes an armrest, a fixed gear coupled to a top of a storage compartment in the armrest console, an elevating gear coupled to the armrest; a dampener gear engaged with the elevating gear and the fixed gear, and a gear connector to receive the elevating gear and the dampener gear. When the armrest is rotated about an axis of the elevating gear in a counterclockwise direction to open, the elevating gear is rotated in the counterclockwise direction and the dampener gear is rotated in a clockwise direction and both the elevating gear and the dampener gear are rotated about an axis of the fixed gear, and wherein the elevating gear and the dampener gear are moved up at a height direction when the armrest is rotated to open.

Abstract: An air register knob assembly comprises a vane having a first side and a second side opposite the first side; a knob having a main body. The main body is slidably connected to only the first side of the vane.

Abstract: Systems and methods for multi-robot gradient-based adaptive navigation are provided.