Patents by Inventor Michael O. Boylan

Michael O. Boylan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230020626
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: June 24, 2022
    Publication date: January 19, 2023
    Inventors: M. Michael WOLFE, Michael O. BOYLAN
  • Patent number: 11400135
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: August 2, 2022
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20200155649
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: February 4, 2020
    Publication date: May 21, 2020
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 10548951
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: February 4, 2020
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 10538586
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: January 21, 2020
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 10196441
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: February 5, 2019
    Assignee: THE METROHEALTH SYSTEM
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20180030133
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: September 25, 2017
    Publication date: February 1, 2018
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20180028618
    Abstract: The present disclosure is directed to the treatment of diseases or conditions characterized by the buildup of fatty tissue, or hyperphagia, such as Prader-Willi syndrome, obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain, weight loss, and/or reduction in fatty tissue, and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: September 25, 2017
    Publication date: February 1, 2018
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Patent number: 9771422
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: September 26, 2017
    Assignee: MHS CARE-INNOVATION LLC
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20170044254
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: October 26, 2016
    Publication date: February 16, 2017
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20150166657
    Abstract: The present disclosure is directed to the treatment of diseases or conditions involving the buildup of fatty tissues, such as obesity, metabolic syndrome, type II diabetes, etc. A composition containing a monoclonal antibody directed against gastric inhibitory polypeptide is administered. This results in a reduced rate of weight gain and a marked decrease in lipid synthesis and accumulation.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 18, 2015
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20040029805
    Abstract: The present invention concerns the use of various forms of GIP-receptor antagonists to attenuate the insulin response to GIP following meals in animals, such as humans, to prevent, reduce, inhibit and/or treat nonalcoholic fatty liver disease by virtue of its prevention and/or reversal of hyperinsulinemia and insulin resistance. Thus, the use of the GIP-receptor antagonists in any effective form is believed to prevent the development and reverse the process of NAFLD. The present invention is accomplished by administering an effective amount of an antagonistic agent, such as a GIP antagonist or an antisense molecule, to antagonize, block, inhibit or ablate the receptor to Glucose-Dependent Insulinotropic Polypeptide (GIP).
    Type: Application
    Filed: June 13, 2003
    Publication date: February 12, 2004
    Inventors: M. Michael Wolfe, Michael O. Boylan
  • Publication number: 20030157071
    Abstract: The present invention is directed to methods for hormone delivery to patients suffering from a condition associated with a hormone deficiency. The method involves transducing stem cells, such as bone marrow derived stem cells, with a hormone gene under the control of a cell-type specific promoter such as the glucose-responsive GIP promoter, such that the hormone gene is expressed only after the stem cells differentiate into the cells which express the cell-type specific promoter, and administering the stem cells to the patient. A preferred embodiment of the present invention is the use of GIP-insulin gene expression in K cells of the gut to treat diabetes.
    Type: Application
    Filed: May 31, 2002
    Publication date: August 21, 2003
    Inventors: M. Michael Wolfe, Lisa I. Jepeal, Michael O. Boylan