Abstract: The invention provides compositions and methods for treating a disease or disorder associate with vascular endothelial growth factor (VEGF). Specifically, the invention relates to an oligomerized VEGF binding domain to provide VEGF antagonism, and thereby treat diseases associated thereof.

Abstract: The invention provides compositions and methods for treating a disease or disorder associate with vascular endothelial growth factor (VEGF). Specifically, the invention relates to an oligomerized VEGF binding domain to provide VEGF antagonism, and thereby treat diseases associated thereof.

Abstract: The invention provides compositions and methods for treating a disease or disorder associated with vascular endothelial growth factor (VEGF). Specifically, the invention relates to an oligomerized VEGF binding domain to provide VEGF antagonism, and thereby treat diseases associated thereof.

Abstract: The present disclosure provides methods for increasing muscle contractility in a myotubular myopathy subject following administration of fewer than 20 doses of a chimeric polypeptide that has a myotubularin protein and an internalizing moiety.

Abstract: A liquid crystal panel and method are disclosed for increasing optical efficiency in the panel by using a reflector with a high fill factor and arranging an array of transparent pixel electrodes between the reflector and a layer of liquid crystal.

Abstract: The invention provides compositions and methods for treating a disease or disorder associated with vascular endothelial growth factor (VEGF). Specifically, the invention relates to an oligomerized VEGF binding domain to provide VEGF antagonism, and thereby treat diseases associated thereof.

Abstract: A holographic data storage system that includes a write head that includes a pixellated spatial light modulator and a separate or integral phase mask that varies the phase depending on the location in the phase mask that light passes through. The phase variation can be changed over time in a random, pseudo-random, or predetermined fashion. The spatial light modulator and phase mask can be implemented in a liquid crystal SLM (nematic, ferroelectric, or other), in a DMD SLM, in a magneto-optical SLM, or in any other suitable manner.

Abstract: A spatial light modulator (SLM) having a phase mask that is provided as an internal component thereof. The phase mask can be provided as a multilevel surface of relatively higher index of refraction material on an inner surface of a transmissive cover window or as a separate transmissive window between the cover window and the pixels of the SLM. If the phase mask is to be used with a liquid crystal SLM, then it may be desirable to planarize the surface of the cover window contacting the liquid crystal by providing a layer of relatively lower index of refraction material adjacent the multilevel surface. The phase mask can also be provided on the transmissive cover window by patterned ion deposition, exposing patterned light to a photopolymeric material, or in some other suitable fashion. Arranging for the pixel electrodes to be at one of multiple levels rather than lying in an exactly planar relationship can also effectively create the phase mask.

Abstract: Apparatus for electrical stunning and killing poultry comprises a conveyor (31) and means for applying electrical voltage across the heads of the birds (3; 37; 42). In one embodiment, means are also provided for applying a voltage between the bird's head and rear by means of a further electrode (4). In this case, a two stage stun and kill process is used, with the bird being stunned by a voltage applied to it across its head and then killed by a voltage applied between its head and rear, causing fibrillation of the heart. The apparatus may also include means (5; 34) for restraining the bird's heads and/or facilitating contact of the bird's heads with the electrodes. The electrodes themselves may take a number of forms, including dry resilient foam covered by a conductive wire mesh, or a number of parallel sprung pins, or a rail along which the bird's heads slide, or a conductive endless belt. A pair of manual stunning tongs (61) is also described.

Abstract: Apparatus for electrical stunning and killing poultry comprises a conveyor (31) and means for applying electrical voltage across the heads of the birds (3; 37; 42). In one embodiment, means are also provided for applying a voltage between the bird's head and rear by means of a further electrode (4). In this case, a two stage stun and kill process is used, with the bird being stunned by a voltage applied to it across its head and then killed by a voltage applied between its head and rear, causing fibrillation of the heart. The apparatus may also include means (5; 34) for restraining the bird's heads and/or facilitating contact of the bird's heads with the electrodes. The electrodes themselves may take a number of forms, including dry resilient foam covered by a conductive wire mesh, or a number of parallel sprung pins, or a rail along which the bird's heads slide, or a conductive endless belt. A pair of manual stunning tongs (61) is also described.