Patents by Inventor Michael O. Favorov

Michael O. Favorov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for detecting anti-hepatitis E virus activity
    Patent number: 6022685
    Abstract: The present invention provides antigenic peptides and polypeptides of hepatitis E virus. Also provided are mixtures of conjugated and unconjugated peptides of the present invention. Methods of detecting hepatitis E viral infection in a subject using the peptides and peptide mixtures of the present invention are also contemplated.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 8, 2000
    Assignee: United States of America
    Inventors: Howard A. Fields, Michael O. Favorov, Yuri E. Khudyakov
  • Methods and compositions for detecting anti-hepatitis E virus activity
    Patent number: 5736315
    Abstract: The present invention provides antigenic peptides and polypeptides of hepatitis E virus. Also provided are mixtures of conjugated and unconjugated peptides of the present invention. Methods of detecting hepatitis E viral infection in a subject using the peptides and peptide mixtures of the present invention are also contemplated.
    Type: Grant
    Filed: October 21, 1992
    Date of Patent: April 7, 1998
    Assignee: National Institute of Health
    Inventors: Howard A. Fields, Michael O. Favorov, Yuri E. Khudyakov
  • Mosaic polypeptide and methods for detecting the hepatitis E virus
    Patent number: 5563032
    Abstract: A nucleic acid encoding a mosaic hepatitis E virus (HEV) polypeptide, consisting of the nucleotide sequence defined in the Sequence Listing as SEQ ID NO:1 is provided. A nucleic acid encoding epitopes 5, 6, 22, 23, 28 and 29 of hepatitis E virus and substantially lacking the nucleic acids intervening the epitope-coding nucleic acids in the native hepatitis E virus is also provided. An isolated nucleic acid that selectively hybridizes under stringent conditions with the mosaic polypeptide-encoding nucleic acid and has at least 70% sequence identity with SEQ ID NO:1 is provided. Also provided are such nucleic acids having at least 80%, 90% and 95% sequence identity. A polypeptide consisting essentially of the amino acid sequence defined in the Sequence Listing as SEQ ID NO:2 is provided.
    Type: Grant
    Filed: February 15, 1994
    Date of Patent: October 8, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Howard A. Fields, Yury E. Khudyakov, Michael O. Favorov