Abstract: A system and a method are disclosed for a data processing apparatus (200) is described which comprises a plurality of application programs (206, 210) configured to utilize an availability status of a user; and a presence engine (208). The presence engine (208) is configured to receive data representative of the availability status of the user and generate one or more representations of the received availability status suitable for one or more of the plurality of application programs (206, 210). The one or more representations of the received availability status are made available to the corresponding one or more of the plurality of application programs (206, 210).

Abstract: The invention provides assays to detect sepsis disease states in a subject by determining the relative amount of mitochondrial nucleic acid in the subject. The assays of the invention may include PCR assays, such semi-quantitative or quantitative PCR involving the co-amplification of a mitochondrial sequence and a reference sequence, such as a genomic sequence. Information from such assays may be evaluated to provide a ratio of mitochondrial nucleic acid to nuclear nucleic acid in the cells of the subject.