Patents by Inventor Michael Ohlmeyer

Michael Ohlmeyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPOPROTEIN LIPASE-ACTIVATING COMPOSITIONS COMPRISING BENZENE DERIVATIVES
    Publication number: 20110065728
    Abstract: The present invention provides pharmaceutical compositions containing benzene compound(s) represented by General Formula (1) below and, particularly, LPL-activating compositions for use in hyperlipidemia therapeutic and preventive agents, anti-obesity agents, and the like: wherein R1, R2, R3 and R4 are as defined in the specification.
    Type: Application
    Filed: May 14, 2008
    Publication date: March 17, 2011
    Applicant: OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Irina Neagu, Michael Ohlmeyer, Vidyadhar M. Paradkar, Kurt W. Saionz, Koushi Iwata, Takashi Okamura, Tadao Shibutani
  • 2-(1-oxo-1-isoquinolin-2-yl)acetamide derivatives
    Patent number: 7906504
    Abstract: Disclosed herein are 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivative of formula I, or pharmaceutically acceptable salts or solvates thereof wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions comprising 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivatives according to the present invention and their use in therapy.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: March 15, 2011
    Assignee: N.V. Organon
    Inventors: Jeffrey Letourneau, Jui-Hsiang Chan, Patrick Jokiel, Michael Ohlmeyer, Irina Neagu, Christopher Riviello, John Richard Morphy, Susan Elizabeth Napier, Koc-Kan Ho
  • PURINES AS PKC-THETA INHIBITORS
    Publication number: 20110046131
    Abstract: A chemical genus of purines, which are useful as PKC? inhibitors, is disclosed.
    Type: Application
    Filed: October 19, 2007
    Publication date: February 24, 2011
    Inventors: Irina Neagu, Andrew Laird Roughton, Koc-Kan Ho, David Diller, Jui-Hsiang Chan, Michael Ohlmeyer, Celia Kingsbury, Johannes Petrus Maria Lommerse, Neeltje Miranda, Jacobus Cornelis Henricus Maria Wijkmans
  • Quinazolinone and isoquinolinone acetamide derivatives
    Patent number: 7820649
    Abstract: Disclosed herein are quinazolinone or isoquinolinone derivatives of formula I, or pharmaceutically acceptable salts or solvates thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions comprising quinazolinone or isoquinolinone according to the present invention and its use in therapy.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: October 26, 2010
    Assignee: N.V. Organon
    Inventors: Jeffrey Letourneau, Patrick Jokiel, Susan Elizabeth Napier, Koc-Kan Ho, Michael Ohlmeyer, Duncan Robert McArthur, Fiona Jeremiah, Paul David Ratcliffe, Jurgen Schulz
  • 2-(4-oxo-4H-quinazolin-3-yl)acetamides and their use as vasopressin V3 antagonists
    Patent number: 7807686
    Abstract: The present invention relates to 2-(4-oxo4H-quinazolin-3-yl) acetamicle derivatives of formula (I), and to their use as vasopressin V3 antagonists, particularly for the treatment of depression.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: October 5, 2010
    Assignee: N.V. Organon
    Inventors: Jeffrey Letourneau, Christopher Riviello, Koc-Kan Hoc, Jui-Hsiang Chan, Michael Ohlmeyer, Patrick Jokiel, Irina Neagu, John Richard Morphy, Susan Elizabeth Napier
  • N-BENZYL,N'-ARYLCARBONYLPIPERAZINE DERIVATIVES
    Publication number: 20090264416
    Abstract: The present invention relates to N-benzyl,N?-arylcarbonylpiperazine derivatives having the general formula I to pharmaceutical compositions comprising the same, and to the use of a these N-benzyl,N?-arylcarbonylpiperazine derivatives for the manufacture of a medicament for treating or preventing atherosclerosis and related disorders associated with cholesterol and bile acids transport and metabolism.
    Type: Application
    Filed: August 19, 2008
    Publication date: October 22, 2009
    Inventors: Koc-Kan Ho, Andrew Laird Roughton, Irina Neagu, Jui-Hsiang Chan, Nasrin Ansari, Michelle Lee Morris, Yajing Rong, Michael Ohlmeyer, Andrew John Cooke, Andrew Stanley Edwards, David Jonathan Bennett
  • 2-(4-Oxo-4H-Quinazolin-3-Yl) Acetamides and Their Use as Vasopressin V3 Antagonists
    Publication number: 20080214553
    Abstract: The present invention relates to 2-(4-oxo4H-quinazolin-3-yl)acetamicle derivatives of formula (I), and to their use as vasopressin V3 antagonists, particularly for the treatment of depression.
    Type: Application
    Filed: March 10, 2006
    Publication date: September 4, 2008
    Inventors: Jeffrey Letourneau, Christopher Riviello, Koc-Kan Ho, Jui-Hsiang Chan, Michael Ohlmeyer, Patrick Jokiel, Irina Neagu, John Richard Morphy, Susan Elizabeth Napier
  • QUINAZOLINONE AND ISOQUINOLINONE ACETAMIDE DERIVATIVES
    Publication number: 20080090802
    Abstract: Disclosed herein are quinazolinone derivatives of formula I, or pharmaceutically acceptable salts or solvates thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions comprising quinazolinone or isoquinolinone according to the present invention and its use in therapy.
    Type: Application
    Filed: September 10, 2007
    Publication date: April 17, 2008
    Applicant: N.V. Organon
    Inventors: Jeffrey Letourneau, Patrick Jokiel, Susan Napier, Koc-Kan Ho, Michael Ohlmeyer, Duncan McArthur, Fiona Jeremiah, Paul Ratcliffe, Jurgen Schulz
  • Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
    Publication number: 20080085909
    Abstract: A chemical genus of purinones and 1H-imidazopyridinones, which are useful as PKC? inhibitors, and their methods of use are disclosed.
    Type: Application
    Filed: February 2, 2007
    Publication date: April 10, 2008
    Applicant: Pharmacopeia Drug Discovery, Inc.
    Inventors: Andrew Roughton, Yajing Rong, Koc Kan Ho, Michael Ohlmeyer, David Diller
  • 8-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE DERIVATIVES FOR IMMUNOSUPPRESSION
    Publication number: 20080085898
    Abstract: The present invention provides novel purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 10, 2008
    Applicant: PHARMACOPEIA, INC.
    Inventors: Yingchun Lu, Celia Kingsbury, Adolph Bohnstedt, Michael Ohlmeyer, Vidyadhar Paradkar
  • 2-(1-OXO-1H-ISOQUINOLIN-2-YL)ACETAMIDE DERIVATIVES
    Publication number: 20080064678
    Abstract: Disclosed herein are 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivative of formula I, or pharmaceutically acceptable salts or solvates thereof wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions comprising 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivatives according to the present invention and their use in therapy.
    Type: Application
    Filed: September 10, 2007
    Publication date: March 13, 2008
    Applicant: N.V. Organon
    Inventors: Jeffrey Letourneau, Jui-Hsiang Chan, Patrick Jokiel, Michael Ohlmeyer, Irina Neagu, Christopher Riviello, John Morphy, Susan Napier, Koc-Kan Ho
  • NITROGEN HETEROCYCLE BIARYLS FOR OSTEOPOROSIS AND OTHER DISEASES
    Publication number: 20080051423
    Abstract: Nitrogen heterocycle biaryls having a carboxylate terminus are useful for treating endometriosis, osteoporosis, restenosis following angioplasty, rheumatoid arthritis, cancer, macular degeneration and obesity. Compounds of formula: are disclosed.
    Type: Application
    Filed: August 23, 2007
    Publication date: February 28, 2008
    Applicant: PHARMACOPEIA, INC.
    Inventors: Jeffrey Letourneau, Vidyahar Paradkar, Michael Ohlmeyer, Lawrence Dillard, John Baldwin, Christopher Riviello, Angela Wong, Yaing Rong
  • Compounds with medicinal effects due to interaction with the glucocorticoid receptor
    Publication number: 20070149577
    Abstract: The invention provides for compounds having the structure according to the formula I wherein: X is a carbon or nitrogen atom; Ar is phenyl or heteroaromatic ring; R1 is hydrogen, halogen, CN or (1C-4C)alkyl; R2 is hydrogen, halogen or optionally fluorinated (1C-3C)alkoxy; R3 and R5 are independently hydrogen, optionally halogenated (1C-4C)alkyl, optionally halogenated (1C-4C)alkoxy, optionally halogenated aryl(1C-4C)alkoxy, optionally halogenated (1C-4C)alkenyl or hydroxylmethyl; R4 is hydrogen, halogen, optionally halogenated (1C-4C)alkoxy or optionally halogenated aryl(1C-4C)alkoxy; R6 is hydrogen, benzyl, optionally substituted with one or more halogens or (1C-4C)alkyl, or R6 is optionally halogenated (1C-4C)alkyl; each R7 independently is hydrogen, halogen, optionally halogenated (1C-4C)alkyl or optionally halogenated (1C-4C)alkoxy and pharmaceutically suitable acid addition salts thereof for use as glucocorticoid receptor modulators, in particular for treatment of central nervous system disorders.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 28, 2007
    Applicants: N.V. Organon, Pharmacopeia Drug Discovery Inc.
    Inventors: Niall Hamilton, Simon Grove, Michael Kiczun, John Morphy, Brad Sherborne, Peter Littlewood, Angus Brown, Celia Kingsbury, Michael Ohlmeyer, Koc-Kan Ho, Steven Kultgen
  • Azinone and diazinone V3 inhibitors for depression and stress disorders
    Publication number: 20070037822
    Abstract: Substituted pyridines, pyrimidines, pyrazines, pyridinones, pyrimidinones, pyrazinones and phenylacetamides useful in treating depression, stress and other disorders are disclosed. The compounds are of the formualae: Other embodiments are also disclosed.
    Type: Application
    Filed: June 7, 2006
    Publication date: February 15, 2007
    Applicant: Pharmacopeia Drug Discovery, Inc.
    Inventors: Jeffrey Letourneau, Koc-Kan Ho, Michael Ohlmeyer, Patrick Jokiel, Christopher Riviello
  • Purine and imidazopyridine derivatives for immunosuppression
    Publication number: 20070021443
    Abstract: The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: April 5, 2006
    Publication date: January 25, 2007
    Inventors: Michael Ohlmeyer, Adolph Bohnstedt, Celia Kingsbury, Koc-Kan Ho, Jorge Quintero, Ming You, Haengsoon Park, Yingchun Lu
  • Nitrogen heterocycle biaryls for osteoporosis and other diseases
    Publication number: 20050222203
    Abstract: Nitrogen heterocycle biaryls having a carboxylate terminus are useful for treating endometriosis, osteoporosis, restenosis following angioplasty, rheumatoid arthritis, cancer, macular degeneration and obesity. Compounds of formula: are disclosed.
    Type: Application
    Filed: February 10, 2004
    Publication date: October 6, 2005
    Applicant: Pharmacopeia, Inc.
    Inventors: Jeffrey Letourneau, Vidyahar Paradkar, Michael Ohlmeyer, Lawrence Dillard, John Baldwin, Christopher Riviello, Angela Wong, Yaing Rong