Patents by Inventor Michael Overduin

Michael Overduin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUNCTIONAL DERIVATIVES OF MALEIMIDE COPOLYMERS FOR NANODISC PRODUCTION
    Publication number: 20220347114
    Abstract: Amphiphilic copolymers and compositions including amphiphilic copolymers. The amphiphilic copolymers include modified maleimide subunits, for example, as illustrated by the structures of Formula IA and Formula IB. The compositions form water-soluble complexes upon association with biological material wherein such biological material can include lipids or membrane proteins. Methods for producing, purifying, analyzing, and using the compositions and complexes are provided.
    Type: Application
    Filed: October 23, 2020
    Publication date: November 3, 2022
    Applicant: The Governors of the University of Alberta
    Inventors: Michael OVERDUIN, Mansoore ESMAILI
  • Solubilisation of membrane proteins
    Patent number: 8754168
    Abstract: A method is provided for solubilising a membrane protein. The method is applied to cellular material comprising the membrane protein and an associated membrane lipid. A copolymer of styrene and maleic acid, wherein the styrene:maleic acid ratio is between 1:2 and 10:1, is mixed with the cellular material to cause the copolymer, lipid and protein to form soluble macromolecular assemblies.
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: June 17, 2014
    Assignee: The University of Birmingham
    Inventors: Timothy Dafforn, Michael Overduin, Timothy Knowles
  • SOLUBILISATION OF MEMBRANE PROTEINS
    Publication number: 20120142861
    Abstract: A method is provided for solubilising a membrane protein. The method is applied to cellular material comprising the membrane protein and an associated membrane lipid. A copolymer of styrene and maleic acid, wherein the styrene:maleic acid ratio is between 1:2 and 10:1, is mixed with the cellular material to cause the copolymer, lipid and protein to form soluble macromolecular assemblies.
    Type: Application
    Filed: July 8, 2010
    Publication date: June 7, 2012
    Inventors: Timothy Dafforn, Michael Overduin, Timothy Knowles