Patents by Inventor Michael OVERSTREET

Michael OVERSTREET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific PD-1 and TIGIT binding proteins and uses thereof
    Patent number: 11939382
    Abstract: The disclosure relates to binding proteins, including antibodies, that bind to Programmed Death-1 (“PD-1”) and T cell immunoreceptor with Ig and ITIM domains (“TIGIT”). The disclosure also provides compositions comprising such binding proteins and nucleic acid molecules encoding such binding proteins. The disclosure further relates to methods of treating a disorder or condition using such binding proteins.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: March 26, 2024
    Assignee: MedImmune, LLC
    Inventors: Yariv Mazor, Yue Wang, Gordon Moody, Deepali Malhotra, Michael Overstreet, Eleanor Clancy-Thompson, Karin Lee, Stacy Pryts, Scott Hammond
  • METHODS FOR GENERATING PRIMARY IMMUNE CELLS
    Publication number: 20230279352
    Abstract: The disclosure relates to methods, cells, and compositions for preparing cell populations and compositions for adoptive cell therapy. In particular, provided herein are methods for expansion and proliferation of primary immune cells including T cell populations.
    Type: Application
    Filed: August 23, 2022
    Publication date: September 7, 2023
    Inventors: DEEPALI MALHOTRA, MICHAEL OVERSTREET, GORDON MOODY, MARK COBBOLD
  • BISPECIFIC PD-1 AND TIGIT BINDING PROTEINS AND USES THEROF
    Publication number: 20220411509
    Abstract: The disclosure relates to binding proteins, including antibodies, that bind to Programmed Death-1 (“PD-1”) and T cell immunoreceptor with Ig and ITIM domains (“TIGIT”). The disclosure also provides compositions comprising such binding proteins and nucleic acid molecules encoding such binding proteins. The disclosure further relates to methods of treating a disorder or condition using such binding proteins.
    Type: Application
    Filed: April 29, 2022
    Publication date: December 29, 2022
    Applicant: MedImmune, LLC
    Inventors: Yariv MAZOR, Yue WANG, Gordon MOODY, Deepali MALHOTRA, Michael OVERSTREET, Eleanor CLANCY-THOMPSON, Karin LEE, Stacy PRYTS, Scott HAMMOND