Patents by Inventor Michael Owen Delaney

Michael Owen Delaney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS
    Publication number: 20090280567
    Abstract: RNA molecules, including siRNA molecules and related control, trackability and exaequo agents with specific stability modifications are provided. These molecules are particularly advantageous as transfection control reagents. The molecules include first and second 5? terminal sense nucleotides with 2?-O-alkyl groups and a label on the first 5? terminal sense nucleotide, in conjunction with at least one additional 2?-O-alkyl pyrimidine modified sense nucleotide, and either: (i) at least one 2? fluoro modified pyrimidine antisense nucleotide and a phosphorylated first 5? terminal antisense nucleotide; or (ii) a first and second 5? terminal antisense nucleotide with 2?-O-alkyl modifications and at least one additional 2?-O-alkyl pyrimidine modified antisense nucleotide.
    Type: Application
    Filed: June 17, 2009
    Publication date: November 12, 2009
    Applicant: DHARMACON, INC.
    Inventors: Devin Leake, Anastasia Khvorova, Yuriy Fedorov, Michael Owen Delaney, Barbara Robertson, Emily Anderson, Angela Reynolds