Patents by Inventor Michael P. Emery
Michael P. Emery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9250164Abstract: Disclosed herein are systems and methods for the developing of immuno-stained biological samples. The systems disclosed herein are automated and are configured to control one or more steps of the developing procedure. Reagents may be added using automatic syringe dispensing. Reagent temperature, reagent stirring, and wash procedures are programmable and can be separately controlled for separate immuno-staining procedures that are performed at the same time.Type: GrantFiled: February 5, 2014Date of Patent: February 2, 2016Assignee: Vertex Pharmaceuticals, IncorporatedInventors: Michael P. Emery, Matthew C. Wallace, James E. Sinclair, Raymond J. Gonzales, Brian Grot, Sanjay Shivayogi Magavi
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Publication number: 20140154151Abstract: Disclosed herein are systems and methods for the developing of immuno-stained biological samples. The systems disclosed herein are automated and are configured to control one or more steps of the developing procedure. Reagents may be added using automatic syringe dispensing. Reagent temperature, reagent stirring, and wash procedures are programmable and can be separately controlled for separate immuno-staining procedures that are performed at the same time.Type: ApplicationFiled: February 5, 2014Publication date: June 5, 2014Applicant: Vertex Pharmaceuticals, IncorporatedInventors: Michael P. Emery, Matthew C. Wallace, James E. Sinclair, Raymond J. Gonzales, Brian Grot, Sanjay Shivayogi Magavi
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Patent number: 8679406Abstract: Disclosed herein are systems and methods for the developing of immuno-stained biological samples. The systems disclosed herein are automated and are configured to control one or more steps of the developing procedure. Reagents may be added using automatic syringe dispensing. Reagent temperature, reagent stirring, and wash procedures are programmable and can be separately controlled for separate immuno-staining procedures that are performed at the same time.Type: GrantFiled: December 4, 2012Date of Patent: March 25, 2014Assignee: Vertex Pharmaceuticals, IncorporatedInventors: Michael P. Emery, Matthew C. Wallace, James E. Sinclair, Raymond J. Gonzales, Brian Grot, Sanjay Shivayogi Magavi
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Patent number: 8353969Abstract: Methods and devices for controlled evaporation of solvent from a solution are provided. In one embodiment, a method for controlled evaporation of solvent from at least one solution includes filling a selected first set of wells in a multi-well plate with a first solution comprising at least one first solvent. The method also includes attaching an inlet manifold to the plate, the inlet manifold comprising an inlet port connected to and in fluid communication only with each of the wells in the selected first set of wells. The method further includes attaching an exhaust manifold to the plate, the exhaust manifold comprising an exhaust port connected to and in fluid communication only with each of the wells in the selected first set of wells. The method also includes introducing a gas into the inlet port and removing solvent vapor from the selected first set of wells.Type: GrantFiled: May 25, 2012Date of Patent: January 15, 2013Assignee: Vertex Pharmaceuticals IncorporatedInventors: Jack Barger, James Sinclair, Michael P. Emery
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Patent number: 8337754Abstract: Disclosed herein are systems and methods for the developing of immuno-stained biological samples. The systems disclosed herein are automated and are configured to control one or more steps of the developing procedure. Reagents may be added using automatic syringe dispensing. Reagent temperature, reagent stirring, and wash procedures are programmable and can be separately controlled for separate immuno-staining procedures that are performed at the same time.Type: GrantFiled: December 22, 2009Date of Patent: December 25, 2012Assignee: Vertex Pharmaceuticals, IncorporatedInventors: Michael P. Emery, Matthew C. Wallace, James E. Sinclair, Raymond J. Gonzales, Brian Grot, Sanjay S. Magavi
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Publication number: 20120241100Abstract: Methods and devices for controlled evaporation of solvent from a solution are provided. In one embodiment, a method for controlled evaporation of solvent from at least one solution includes filling a selected first set of wells in a multi-well plate with a first solution comprising at least one first solvent. The method also includes attaching an inlet manifold to the plate, the inlet manifold comprising an inlet port connected to and in fluid communication only with each of the wells in the selected first set of wells. The method further includes attaching an exhaust manifold to the plate, the exhaust manifold comprising an exhaust port connected to and in fluid communication only with each of the wells in the selected first set of wells. The method also includes introducing a gas into the inlet port and removing solvent vapor from the selected first set of wells.Type: ApplicationFiled: May 25, 2012Publication date: September 27, 2012Applicant: Vertex Pharmaceuticals IncorporatedInventors: Jack Barger, James Sinclair, Michael P. Emery
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Patent number: 8206659Abstract: Methods and devices for controlled evaporation of solvent from a solution are provided. In one embodiment, the device can control evaporation of different solutions comprising solvents of dissimilar volatilities simultaneously. In another embodiment, control over the flow of solvent vapor out of the device is provided by selecting the pressure at an inlet port and an exhaust port of the device. In yet another embodiment, control over the flow of solvent vapor out of the device is provided by selecting the size of a disk flow control orifice positioned between the wells and a vapor removal outlet of the device. In still another embodiment, control over the flow of solvent vapor out of the device is provided by the opening and closing of the vapor removal outlet of the device. In yet a further embodiment, the rate of evaporation of solvent is controlled by controlling the temperature of the solution.Type: GrantFiled: June 12, 2009Date of Patent: June 26, 2012Assignee: Vertex Pharmaceuticals IncorporatedInventors: Jack Barger, James Sinclair, Michael P. Emery
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Publication number: 20110151482Abstract: Disclosed herein are systems and methods for the developing of immuno-stained biological samples. The systems disclosed herein are automated and are configured to control one or more steps of the developing procedure. Reagents may be added using automatic syringe dispensing. Reagent temperature, reagent stirring, and wash procedures are programmable and can be separately controlled for separate immuno-staining procedures that are performed at the same time.Type: ApplicationFiled: December 22, 2009Publication date: June 23, 2011Inventors: Michael P. Emery, Matthew C. Wallace, James E. Sinclair, Raymond J. Gonzales, Brian Grot, Sanjay S. Magavi
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Patent number: 7919047Abstract: An air displacement pipetter comprises a guidance sleeve positioned within a hole in a cylinder block and a piston within a portion of the guidance sleeve a piston penetrating the cylinder block, a spring energized seal disposed within the cylinder block, a seal capture plate contacting the spring energized seal, a carrier plate, a pipette tip attached to the carrier plate, and a manifold plate between said carrier plate and said cylinder block.Type: GrantFiled: June 5, 2006Date of Patent: April 5, 2011Assignee: Vertex Pharmaceuticals IncorporatedInventors: James E. Sinclair, Michael P. Emery, Minh Vuong
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Publication number: 20100314051Abstract: Methods and devices for controlled evaporation of solvent from a solution are provided. In one embodiment, the device can control evaporation of different solutions comprising solvents of dissimilar volatilities simultaneously. In another embodiment, control over the flow of solvent vapor out of the device is provided by selecting the pressure at an inlet port and an exhaust port of the device. In yet another embodiment, control over the flow of solvent vapor out of the device is provided by selecting the size of a disk flow control orifice positioned between the wells and a vapor removal outlet of the device. In still another embodiment, control over the flow of solvent vapor out of the device is provided by the opening and closing of the vapor removal outlet of the device. In yet a further embodiment, the rate of evaporation of solvent is controlled by controlling the temperature of the solution.Type: ApplicationFiled: June 12, 2009Publication date: December 16, 2010Applicant: Vertex Pharmaceuticals IncorporatedInventors: Jack Barger, James Sinclair, Michael P. Emery
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Patent number: 7490513Abstract: A liquid level sensor comprises a plurality of electrodes arranged in a defined relationship with respect to a container filling trajectory, a signal generator coupled to one or more of the plurality of electrodes, a signal receiver coupled to one or more of the plurality of electrodes, and a sensing circuit coupled to at least one of the signal generator and signal receiver. The sensing circuit is configured to produce an output indicative of electrical resistance between at least one pair of the plurality of electrodes. The sensing circuit may be associated with the signal receiver and/or with the signal generator.Type: GrantFiled: May 10, 2007Date of Patent: February 17, 2009Assignee: Vertex Pharmaceuticals, Inc.Inventors: Philip E. Salzmann, Alec T. Harootunian, Michael P. Emery, Javier H. Flores, Todd N. Bennett, Minh Vuong
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Publication number: 20070207062Abstract: An air displacement pipetter comprises a guidance sleeve positioned within a hole in a cylinder block and a piston within a portion of the guidance sleeve a piston penetrating the cylinder block, a spring energized seal disposed within the cylinder block, a seal capture plate contacting the spring energized seal, a carrier plate, a pipette tip attached to the carrier plate, and a manifold plate between said carrier plate and said cylinder block.Type: ApplicationFiled: June 5, 2006Publication date: September 6, 2007Inventors: James E. Sinclair, Michael P. Emery, Minh Vuong
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Patent number: 7219545Abstract: A liquid level sensor comprises a plurality of electrodes arranged in a defined relationship with respect to a container filling trajectory, a signal generator coupled to one or more of the plurality of electrodes, a signal receiver coupled to one or more of the plurality of electrodes, and a sensing circuit coupled to at least one of the signal generator and signal receiver. The sensing circuit is configured to produce an output indicative of electrical resistance between at least one pair of the plurality of electrodes. The sensing circuit may be associated with the signal receiver and/or with the signal generator.Type: GrantFiled: July 28, 2004Date of Patent: May 22, 2007Assignee: Vertex Pharmaceuticals, Inc.Inventors: Philip E. Salzmann, Alec T. Harootunian, Michael P. Emery, Javier H. Flores, Todd N. Bennett, Minh Vuong