Patents by Inventor Michael P. Gustafson

Michael P. Gustafson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210405049
    Abstract: This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4+ lymphocytes, CD8+ lymphocytes, regulatory T cells, B cells, NK cells, granulocytes, CD14+HLA-DRlo/neg monocytes, and/or CD86+ monocytes per unit volume (e.g., cells per ?L or mL) of whole blood (e.g., fresh, un-manipulated whole blood) obtained from a mammal (e.g., a human) are provided.
    Type: Application
    Filed: September 10, 2021
    Publication date: December 30, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson
  • Patent number: 11143653
    Abstract: This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4+ lymphocytes, CD8+ lymphocytes, regulatory T cells, B cells, NK cells, granulocytes, CD14+HLA-DRlo/neg g monocytes, and/or CD86+ monocytes per unit volume (e.g., cells per ?L or mL) of whole blood (e.g., fresh, un-manipulated whole blood) obtained from a mammal (e.g., a human) are provided.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: October 12, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson
  • Publication number: 20210154234
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Application
    Filed: January 12, 2021
    Publication date: May 27, 2021
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Patent number: 10925901
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: February 23, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Publication number: 20190209617
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 11, 2019
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Publication number: 20190086415
    Abstract: This document provides methods and materials for treating patients following an assessment of immune subtypes such as an assessment of peripheral blood phenotypes. For example, methods and materials for treating a mammal having a medical condition after assessing a mammal's level of CD14+/DR? cells (e.g., CD14+/DR? monocytes) and level of CD4+ cells (e.g., CD4+ T cells) and classifying the mammal has being likely to experience a favorable or unfavorable medical outcome based at least in part on the mammal's level of CD14+/DR? cells and level of CD4+ cells are provided.
    Type: Application
    Filed: September 21, 2018
    Publication date: March 21, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson, Yi Lin
  • Patent number: 10166258
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: January 1, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Patent number: 10094835
    Abstract: This document provides methods and materials for treating patients following an assessment of immune subtypes such as an assessment of peripheral blood phenotypes. For example, methods and materials for treating a mammal having a medical condition after assessing a mammal's level of CD14+/DR? cells (e.g., CD14+/DR? monocytes) and level of CD4+ cells (e.g., CD4+ T cells) and classifying the mammal has being likely to experience a favorable or unfavorable medical outcome based at least in part on the mammal's level of CD14+/DR? cells and level of CD4+ cells are provided.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: October 9, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson, Yi Lin
  • Publication number: 20180238879
    Abstract: This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4+ lymphocytes, CD8+ lymphocytes, regulatory T cells, B cells, NK cells, granulocytes, CD14+HLA-DRlo/neg g monocytes, and/or CD86+ monocytes per unit volume (e.g., cells per ?L or mL) of whole blood (e.g., fresh, un-manipulated whole blood) obtained from a mammal (e.g., a human) are provided.
    Type: Application
    Filed: April 13, 2018
    Publication date: August 23, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Allan B. Dietz, Michael P. Gustafson
  • Patent number: 9970936
    Abstract: This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4+ lymphocytes, CD8+ lymphocytes, regulatory T cells, B cells, NK cells, granulocytes, CD14+HLA-DRlo/neg monocytes, and/or CD86+ monocytes per unit volume (e.g., cells per ?L or mL) of whole blood (e.g., fresh, un-manipulated whole blood) obtained from a mammal (e.g., a human) are provided.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: May 15, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Michael P. Gustafson, Allan B. Dietz
  • Publication number: 20160266115
    Abstract: This document provides methods and materials involved in assessing immune system profiles. For example, methods and materials for performing flow cytometry to determine the number of CD4+ lymphocytes, CD8+ lymphocytes, regulatory T cells, B cells, NK cells, granulocytes, CD14+HLA-DRlo/neg monocytes, and/or CD86+ monocytes per unit volume (e.g., cells per ?L or mL) of whole blood (e.g., fresh, un-manipulated whole blood) obtained from a mammal (e.g., a human) are provided.
    Type: Application
    Filed: November 12, 2013
    Publication date: September 15, 2016
    Inventors: Michael P. Gustafson, Allan B. Dietz
  • Publication number: 20160082047
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 24, 2016
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Publication number: 20160077096
    Abstract: This document provides methods and materials for treating patients following an assessment of immune subtypes such as an assessment of peripheral blood phenotypes. For example, methods and materials for treating a mammal having a medical condition after assessing a mammal's level of CD14+/DR? cells (e.g., CD14+/DR? monocytes) and level of CD4+ cells (e.g., CD4+ T cells) and classifying the mammal has being likely to experience a favorable or unfavorable medical outcome based at least in part on the mammal's level of CD14+/DR? cells and level of CD4+ cells are provided.
    Type: Application
    Filed: May 7, 2014
    Publication date: March 17, 2016
    Inventors: Allan B. DIETZ, Michael P. GUSTAFSON, Yi LIN
  • Publication number: 20110171731
    Abstract: This document provides methods and materials relating to platelet lysates. For example, methods and materials for using platelet lysate compositions to grow adult stem cells, to differentiate adult stem cells, to grow primary cell cultures, to grow tumor stem cells, and to identify effective growth factors are provided.
    Type: Application
    Filed: September 16, 2009
    Publication date: July 14, 2011
    Inventors: Allan B. Dietz, Michael P. Gustafson, Greg W. Butler
  • Patent number: 6015700
    Abstract: A nucleic acid and corresponding polypeptide that aids in the regulation of the cell cycle in Pneumocystis carinii is described. Antibodies generated against a unique carboxyl-terminus region of the polypeptide have specific binding affinity for P. carinii Cdc2 polypeptide and are benificial in diagnosing and monitoring P. carinii infection in patients. Expression of P. carinii Cdc2 polypeptide in cdc2-mutant yeast and other cdc2-mutant organisms provides a for model for studying the life cycle of P. carinii and for identifying novel therapeutics.
    Type: Grant
    Filed: June 8, 1998
    Date of Patent: January 18, 2000
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Andrew H. Limper, Edward B. Leof, Charles F. Thomas, Michael P. Gustafson
  • Patent number: 5863741
    Abstract: A nucleic acid and corresponding polypeptide that aids in the regulation of the cell cycle in Pneumocystis carinii is described. Antibodies generated against a unique carboxyl-terminus region of the polypeptide have specific binding affinity for P. carinii Cdc2 polypeptide and are beneficial in diagnosing and monitoring P. carinii infection in patients. Expression of P. carinii Cdc2 polypeptide in cdc2-mutant yeast and other cdc2-mutant organisms provides a useful model for studying the life cycle of P. carinii and for identifying novel therapeutics.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: January 26, 1999
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Andrew H. Limper, Edward B. Leof, Charles F. Thomas, Michael P. Gustafson