Patents by Inventor Michael P. LEDBETTER

Michael P. LEDBETTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250066799
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: November 14, 2024
    Publication date: February 27, 2025
    Inventors: Floyd E. ROMESBERG, Michael P. LEDBETTER, Rebekah J. KARADEEMA
  • Publication number: 20250020446
    Abstract: A system for atom interferometry includes one laser configured to generate an output beam; an acousto-optic deflector disposed to generate two diffracted beams that are spatially offset with identical polarizations; and a birefringent crystal disposed to receive the two diffracted beams, where one of the two diffracted beams is passed through a half wave plate so that the two diffracted beams have orthogonal polarizations, where the birefringent crystal further disposed and selected in size to enable the two diffracted beams to re-overlap upon exiting the birefringent crystal by having one of the two diffracted beams walk toward the other of the two diffracted beams in the birefringent crystal, where the two diffracted beams have minimal path length differences so that the two diffracted beams are useable for interferometry.
    Type: Application
    Filed: October 4, 2024
    Publication date: January 16, 2025
    Inventors: Miroslav Y. Shverdin, Matthew Todd Cashen, Micah P. Ledbetter, Michael R. Matthews, Alexander F. Sugarbaker
  • Patent number: 12173291
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: December 24, 2024
    Assignee: The Scripps Research Institute
    Inventors: Floyd E. Romesberg, Michael P. Ledbetter, Rebekah J. Karadeema
  • Publication number: 20240294962
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: December 7, 2023
    Publication date: September 5, 2024
    Inventors: Floyd E. ROMESBERG, Vivian T. DIEN, Aaron W. FELDMAN, Rebekah J. KARADEEMA, Lingjun LI, Michael P. LEDBETTER, Anne Xiaozhou ZHOU
  • Patent number: 11879145
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: January 23, 2024
    Assignee: The Scripps Research Institute
    Inventors: Floyd E. Romesberg, Vivian T. Dien, Aaron W. Feldman, Rebekah J. Karadeema, Lingjun Li, Michael P. Ledbetter, Anne Xiaozhou Zhou
  • Publication number: 20200392550
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 17, 2020
    Inventors: Floyd E. ROMESBERG, Vivian T. DIEN, Aaron W. FELDMAN, Rebekah J. KARADEEMA, Lingjun LI, Michael P. LEDBETTER, Anne Xiaozhou ZHOU
  • Publication number: 20200318122
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 8, 2020
    Inventors: Floyd E. ROMESBERG, Michael P. LEDBETTER, Rebekah J. KARADEEMA