Patents by Inventor Michael P. LEDBETTER

Michael P. LEDBETTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE
    Publication number: 20250066799
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: November 14, 2024
    Publication date: February 27, 2025
    Inventors: Floyd E. ROMESBERG, Michael P. LEDBETTER, Rebekah J. KARADEEMA
  • Unnatural base pair compositions and methods of use
    Patent number: 12173291
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: December 24, 2024
    Assignee: The Scripps Research Institute
    Inventors: Floyd E. Romesberg, Michael P. Ledbetter, Rebekah J. Karadeema
  • REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS
    Publication number: 20240294962
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: December 7, 2023
    Publication date: September 5, 2024
    Inventors: Floyd E. ROMESBERG, Vivian T. DIEN, Aaron W. FELDMAN, Rebekah J. KARADEEMA, Lingjun LI, Michael P. LEDBETTER, Anne Xiaozhou ZHOU
  • Reagents and methods for replication, transcription, and translation in semi-synthetic organisms
    Patent number: 11879145
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: January 23, 2024
    Assignee: The Scripps Research Institute
    Inventors: Floyd E. Romesberg, Vivian T. Dien, Aaron W. Feldman, Rebekah J. Karadeema, Lingjun Li, Michael P. Ledbetter, Anne Xiaozhou Zhou
  • REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS
    Publication number: 20200392550
    Abstract: Disclosed herein are compositions, methods, cells, engineered microorganisms, and kits for increasing the production of proteins or polypeptides comprising one or more unnatural amino acids. Further provided are compositions, cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 17, 2020
    Inventors: Floyd E. ROMESBERG, Vivian T. DIEN, Aaron W. FELDMAN, Rebekah J. KARADEEMA, Lingjun LI, Michael P. LEDBETTER, Anne Xiaozhou ZHOU
  • UNNATURAL BASE PAIR COMPOSITIONS AND METHODS OF USE
    Publication number: 20200318122
    Abstract: Disclosed herein are methods, cells, engineered microorganisms, and kits for increasing the production of polypeptides comprising one or more unnatural amino acids. Further provided are cells, engineered microorganisms, and kits for increasing the retention of unnatural nucleic acids encoding the unnatural amino acids in an engineered cell, or semi-synthetic organism.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 8, 2020
    Inventors: Floyd E. ROMESBERG, Michael P. LEDBETTER, Rebekah J. KARADEEMA