Patents by Inventor Michael P. McGrogan

Michael P. McGrogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELL THERAPY FOR CHRONIC STROKE
    Publication number: 20140099286
    Abstract: A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells in at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at ?170° C. before use.
    Type: Application
    Filed: September 26, 2013
    Publication date: April 10, 2014
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: Paul R. Sanberg, Douglas Kondziolka, Michael P. McGrogan, Gary L. Snable
  • Cell therapy for chronic stroke
    Publication number: 20030211085
    Abstract: A method of treating stroke in a patient who has undergone a stroke comprising administering at least 2 million suitable neuronal cells to at least one brain area involved in the stroke. The method comprises the step of using a twist drill or a burr to form a hole in the skull through which the cells could be administered. Exemplary cells are hNT neuronal cells, HCN-1 cells, fetal pig cells, neural crest cells, neural stem cells, or a combination thereof. Also disclosed herein is a pharmaceutical composition of 95% pure hNT neuronal cells, which composition further includes a vial containing PBS and human neuronal cells. This vial is provided in a container with liquid nitrogen, whereby the composition is frozen and maintained at −170° C. before use.
    Type: Application
    Filed: September 30, 2002
    Publication date: November 13, 2003
    Inventors: Paul R. Sanberg, Douglas Kondziolka, Michael P. McGrogan, Gary L. Snable
  • Recombinant purified protease nexin
    Patent number: 5495001
    Abstract: DNA segments encoding two slightly different protease nexin I forms (PN-I.alpha. and PN-I.beta.) are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I is a serine protease inhibitor useful in controlling conditions mediated by proteolytic activity.
    Type: Grant
    Filed: August 10, 1994
    Date of Patent: February 27, 1996
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Michael P. McGrogan, Randy W. Scott, Joffre B. Baker, Christian C. Simonsen, Sr.
  • Human IL-2 like polypeptides, DNA sequences and recombinant DNA molecules therefore and methods for the production and use thereof
    Patent number: 4939093
    Abstract: DNA sequences and recombinant DNA molecules which encode human IL-2 IL-2 like polypeptides, hosts transformed with vectors carrying the DNA sequences as inserts, methods for their production and therapeutic formulations utilizing the IL-2 and IL-2 like polypeptides are provided.
    Type: Grant
    Filed: August 23, 1988
    Date of Patent: July 3, 1990
    Assignee: Cetus Corporation
    Inventors: Michael P. McGrogan, Ernest S. Kawasaki, Michael V. Doyle, David F. Mark