Patents by Inventor Michael P. Pieper

Michael P. Pieper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140316138
    Abstract: The invention relates to a process for preparing new tiotropium salts, these new tiotropium salts as such, pharmaceutical formulations containing them and their use for preparing a medicament.
    Type: Application
    Filed: July 3, 2014
    Publication date: October 23, 2014
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Mihaela Maria POP, Stéphanie MULDER HOUDAYER, Peter SIEGER, Michael P. PIEPER
  • Publication number: 20140056823
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: November 4, 2013
    Publication date: February 27, 2014
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Thierry BOUYSSOU, Michael P. PIEPER, Andreas SCHNAPP
  • Publication number: 20130189194
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: March 12, 2013
    Publication date: July 25, 2013
    Applicant: Boehringer Ingelheim Inrernational GmbH
    Inventors: Thierry BOUYSSOU, Michael P. Pieper, Andreas Schnapp
  • Publication number: 20120263655
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: June 29, 2012
    Publication date: October 18, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Thierry BOUYSSOU, Michael P. PIEPER, Andreas SCHNAPP
  • Publication number: 20120189556
    Abstract: A pharmaceutical composition comprising an anticholinergic and a steroid, optionally together with a pharmaceutically acceptable excipient, the anticholinergic and the steroid optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: March 29, 2012
    Publication date: July 26, 2012
    Applicant: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
    Inventors: Michel PAIRET, Michael P. PIEPER, Christopher John Montague MEADE, Richard REICHL, Christel SCHMELZER
  • Publication number: 20110135582
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 9, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Thierry BOUYSSOU, Michael P. PIEPER, Andreas SCHNAPP
  • Publication number: 20110076238
    Abstract: The invention relates to the use of anticholinergics for preparing a pharmaceutical composition for the prevention and treatment of proliferative processes.
    Type: Application
    Filed: December 8, 2010
    Publication date: March 31, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: John Edward PARK, Nveed CHAUDHARY, Michael P. PIEPER
  • Publication number: 20110038806
    Abstract: A pharmaceutical composition comprising a compound of formula 1 wherein X? is an anion with a single negative charge, and a betamimetic, optionally together with a pharmaceutically acceptable excipient, the compound of formula 1 and the betamimetic optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: October 26, 2010
    Publication date: February 17, 2011
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Christopher John Montague MEADE, Michel PAIRET, Michael P. PIEPER
  • Patent number: 7867987
    Abstract: A pharmaceutical composition comprising a compound of formula 1 wherein X? is an anion with a single negative charge, and a betamimetic, optionally together with a pharmaceutically acceptable excipient, the compound of formula 1 and the betamimetic optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: January 11, 2011
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christopher John Montague Meade, Michel Pairet, Michael P. Pieper
  • Publication number: 20100330186
    Abstract: A pharmaceutical composition comprising a compound of formula 1 wherein X? is an anion with a single negative charge, and a betamimetic, optionally together with a pharmaceutically acceptable excipient, the compound of formula 1 and the betamimetic optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: September 3, 2010
    Publication date: December 30, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Christopher John Montague MEADE, Michel PAIRET, Michael P. PIEPER
  • Patent number: 7851483
    Abstract: A pharmaceutical composition comprising: (a) a salt of formula 1 wherein: X? is an anion with a single negative charge; and (b) a steroid 2, processes for preparing such pharmaceutical composition, and their use in the treatment of respiratory complaints.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: December 14, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Rolf Banholzer, Helmut Meissner, Gerd Morschhaeuser, Michael P. Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Christopher John Montague Meade, Michel Pairet
  • Publication number: 20100310477
    Abstract: A pharmaceutical composition comprising an anticholinergic and at least one additional active ingredient selected from among corticosteroids, dopamine agonistes, PDE-IV inhibitors, NK1-antagonists, endothelin antagonists, antihistamines, and EGFR-kinase inhibitors, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Application
    Filed: August 13, 2010
    Publication date: December 9, 2010
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. Kg.
    Inventors: Michel Pairet, Michael P. Pieper, Christopher John Montague Meade, Richard Reichl, Christel Schmelzer, Birgit Jung
  • Publication number: 20100234411
    Abstract: The present invention relates to novel pharmaceutical compositions based on telmisartan 1 and anticholinergics 2 processes for preparing them and their use for the treatment of respiratory diseases.
    Type: Application
    Filed: July 14, 2008
    Publication date: September 16, 2010
    Applicant: BOEHRINGER INGELHEIM INTERMATIONAL GMBH
    Inventors: Yunhai Cui, Wolfgang Wienen, Michael P. Pieper
  • Patent number: 7776315
    Abstract: A pharmaceutical composition comprising an anticholinergic and at least one additional active ingredient selected from among corticosteroids, dopamine agonistes, PDE-IV inhibitors, NK1-antagonists, endothelin antagonists, antihistamines, and EGFR-kinase inhibitors, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Grant
    Filed: December 8, 2004
    Date of Patent: August 17, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Michel Pairet, Michael P. Pieper, Christopher John Montague Meade, Richard Reichl, Christel Schmelzer, Birgit Jung
  • Patent number: 7745621
    Abstract: The invention relates to compounds of general formula 1 wherein n, A, B, D, L, R1, R2, R3 and R4 may have the meanings given in the claims and in the specification, processes for preparing them, and their use as pharmaceutical compositions, particularly as pharmaceutical compositions for the treatment of respiratory complaints.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: June 29, 2010
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Matthias Grauert, Thierry Bouyssou, Philipp Lustenberger, Steffen Breitfelder, Andreas Schnapp, Michael P. Pieper, Klaus Rudolf, Georg Speck
  • Publication number: 20100015061
    Abstract: The present invention relates to novel pharmaceutical compositions based on anticholinergics and andolast, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Application
    Filed: December 22, 2006
    Publication date: January 21, 2010
    Applicant: Boehringer Ingeheim International GmnH
    Inventor: Michael P. Pieper
  • Publication number: 20090155185
    Abstract: A pharmaceutical composition comprising an anticholinergic and a betamimetic of formula 2 optionally together with a pharmaceutically acceptable excipient, the anticholinergic and the betamimetic optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of asthma, COPD, or other inflammatory or obstructive respiratory complaints.
    Type: Application
    Filed: January 7, 2009
    Publication date: June 18, 2009
    Inventors: Christopher John Montague Meade, Michel Pairet, Michael P. Pieper, Ingo Konetzki
  • Publication number: 20090088408
    Abstract: The present invention relates to novel pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Application
    Filed: August 29, 2008
    Publication date: April 2, 2009
    Inventors: Christopher J. M. Meade, Michel Pairet, Michael P. Pieper
  • Patent number: 7507745
    Abstract: The present invention relates to novel pharmaceutical compositions based on fluorene carboxylic acid ester derived anticholinergics of formula 1 and soluble TNF receptor fusion proteins, processes for preparing them and their use in the treatment of respiratory diseases.
    Type: Grant
    Filed: January 18, 2005
    Date of Patent: March 24, 2009
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christopher John Montague Meade, Michel Pairet, Michael P. Pieper
  • Publication number: 20080292562
    Abstract: The present invention relates to novel pharmaceutical compositions based on PDE IV inhibitors (2) and salts of formula (1) wherein X may have the meanings defined in the description and claims, and their use in the treatment of respiratory complaints.
    Type: Application
    Filed: June 13, 2005
    Publication date: November 27, 2008
    Inventors: Michael P. Pieper, Michel Pairet