Abstract: A surgical instrument may include a knife moveable from a stowed position completely within said surgical instrument to a cutting position in which at least part of the knife is positioned outside the surgical instrument. The surgical instrument may also include at least two cam slots, a cam pin extending from the knife into the cam slots, at least two guide slots that are substantially linear and are spaced apart from said cam slots, and a guide pin extending from the knife into the guide slots. In some embodiments, the cam slots are shaped to cause the knife to move from the stowed position to the cutting position as the knife is urged proximally.

Abstract: An exemplary surgical apparatus may include an anvil including an outer surface, a channel defined therein, and an aperture defined in the outer surface, where the aperture opens to the channel; and a cutter slidable along and within the channel, where at least a portion of the cutter is flexible. Another exemplary surgical apparatus may include an anvil including an open channel defined therein; and a one-piece cutter including a knife adjacent to a bending region, where the cutter is slidable in the channel; where the knife is initially held completely within the anvil, and where the knife flexes out of the channel and out of the anvil in response to proximal motion of the cutter.

Abstract: One exemplary surgical apparatus may include at least one carrier, staples fixed to a corresponding carrier, and a feeder belt to which at least one carrier is frangibly connected.

Abstract: One exemplary surgical apparatus may include at least one carrier, staples fixed to a corresponding carrier, and a feeder belt to which at least one carrier is frangibly connected. Another exemplary surgical apparatus may include a staple holder, an anvil movably connected to the staple holder, a feeder belt, where at least part of the feeder belt extends into the staple holder, and staples fixed to and frangibly separable from the feeder belt; where the staples are organized into at least two groups spaced apart from one another; and where at least one staple is deployable to a different closed shape than at least one other staple.

Abstract: A surgical method for treating a tissue structure having a wall and a lumen may include providing a substantially rigid anvil and a flexible tip affixed to and extending from the distal end of that anvil; making an incision in the wall of the tissue structure; inserting the flexible tip and at least a portion of the rigid anvil through the incision into the lumen of the tissue structure; and deforming at least one connector, introduced from outside the wall of the tissue structure, against the portion of the rigid anvil located within the lumen of the tissue structure.

Abstract: A tool for treating tissue in conjunction with one or more connectors may include an anvil against which at least one connector is urged, and a flexible tip extending from the distal end of said anvil. At least one connector may be held by a connector holder that is pivotally connected to the anvil. The anvil may be used to treat tissue by making an incision in the wall of the blood vessel, inserting the flexible tip and at least a portion of the anvil through the incision into the lumen of the blood vessel, and deforming at least one connector, introduced from outside the wall of the blood vessel, against the portion of the anvil that is located within the lumen of the blood vessel.