Abstract: Apparatuses, systems, and methods for treating tissue abnormalities are disclosed. The tissue may be visualized for determining a presence of one or more abnormalities contained therein. Imaging data obtained by visualization may be used to determine the presence of one or more abnormalities. Each of the detected abnormalities may be identified and a treatment plan developed for treating the abnormalities. Treatment may be delivered to the abnormalities according to the treatment plan.

Abstract: Mechanical optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A mechanical optical element, such as a rotating prism or a mirror membrane, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: Pixelated array optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A pixelated phase array, such as a digital micromirror device or an LCD phase plate, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: An optical coherence tomography (OCT) apparatus includes an optical source module comprising two or more selectable optical sources or an optical source configured to selectively operate in two or more source operating modes, or a combination of both, and further comprises an OCT engine coupled to the optical source module, the OCT engine comprising an OCT interferometer. The OCT apparatus still further includes a mode-switching optics module coupled to the OCT engine and comprising one or more swappable, selectable, or adjustable optical components, such that the mode-switching optics module is configured to selectively provide two or more optical configurations for the optical path between the OCT engine and an imaged object, according to two or more corresponding operating modes.

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.

Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: Apparatuses, systems, and methods for treating tissue abnormalities are disclosed. The tissue may be visualized for determining a presence of one or more abnormalities contained therein. Imaging data obtained by visualization may be used to determine the presence of one or more abnormalities. Each of the detected abnormalities may be identified and a treatment plan developed for treating the abnormalities. Treatment may be delivered to the abnormalities according to the treatment plan.

Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.

Abstract: An ophthalmic illumination system includes a light source generating a source light beam and a beam splitter splitting the source light beam into first and second light beams. A first attenuator is located in a path of the first light beam and a second attenuator is located in the path of the second light beam, the first and second attenuators operable to change the intensities of the first and second light beams, respectively. A first optical fiber port is configured for connection to a first optical fiber for delivering the first light beam to a patient's eye and a second optical fiber port is configured for connection to a second optical fiber for delivering the second light beam to the patient's eye. A control unit is communicatively coupled to the first and second attenuators and is operable to adjust the attenuators to control the intensities of the light beams delivered to the patient's eye.

Abstract: An optical coherence tomography (OCT) apparatus includes an optical source module comprising two or more selectable optical sources or an optical source configured to selectively operate in two or more source operating modes, or a combination of both, and further comprises an OCT engine coupled to the optical source module, the OCT engine comprising an OCT interferometer. The OCT apparatus still further includes a mode-switching optics module coupled to the OCT engine and comprising one or more swappable, selectable, or adjustable optical components, such that the mode-switching optics module is configured to selectively provide two or more optical configurations for the optical path between the OCT engine and an imaged object, according to two or more corresponding operating modes.

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.

Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: Mechanical optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A mechanical optical element, such as a rotating prism or a mirror membrane, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: Pixelated array optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A pixelated phase array, such as a digital micromirror device or an LCD phase plate, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

Abstract: Frequency-based mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A laser modulator may introduce frequency modulation to laser light to generate a homogeneous illumination field due to increased mode mixing in the optical fiber.

Abstract: A retinal treatment system for delivering therapeutic agents to a target location with a retina is disclosed herein. The retinal treatment system includes a console having a control system and a handheld device coupled to the control system. The handheld device includes an inner tube disposed within an outer tube and being axially moveable within the outer tube. The inner tube has a perforating tip that is configured to perforate an inner limiting membrane of the retina. The handheld device further includes a chamber coupled to a proximal end of the inner tube that is configured to receive a fluid containing therapeutic agents injectable from the perforating tip. The control system of the retinal treatment system permits a user to maintain a position of the handheld device relative to the retina and activate an injection of a portion of the fluid through the inner tube into the retina.

Abstract: An ophthalmic surgical microscope can include a movable optical element positioned in an optical pathway of light reflected from a surgical field. The movable optical element can be configured to oscillate in a direction along the optical pathway. The microscope can include an actuator coupled to the movable optical element and configured to move in response to a control signal. The microscope can include a computing device in communication with the actuator and configured to generate the control signal to move the movable optical element. In some embodiments, the computing device is configured to generate the control signal to move the movable optical element with an oscillation frequency greater than the critical flicker fusion rate.

Abstract: An endoilluminator system includes an endoilluminator probe and an illumination source. The endoilluminator probe includes a nano-scale optical fiber and a probe fiber connector, and the illumination source includes a source fiber connector. The illumination source is configured to produce an illumination spot at the source fiber connector having a diameter smaller than a diameter of a fiber core of the nano-scale optical fiber. The probe fiber connector and the source connector are configured when connected to align the illumination spot off-center relative to the nano-scale optical fiber such that the angular distribution of light emitted by the nano-scale optical fiber is increased relative to aligning the illumination spot at a center of the nano-scale optical fiber.

Abstract: Systems, apparatuses, and methods of and for an ophthalmic visualization system are disclosed. An example ophthalmic visualization system may include a first lens positioned relative to a surgical microscope in a manner facilitating viewing of a central region of a retina through the surgical microscope during a surgical procedure. The first lens may be positionable in an optical path between an eye and the surgical microscope during the surgical procedure. The example ophthalmic visualization system may also include a second lens selectively positionable relative to the surgical microscope and the first lens in a manner facilitating viewing of a peripheral region of the retina of the eye during the surgical procedure. The second lens may be selectively positionable in the optical path such that the peripheral region is selectively viewable without changing the position of the first lens during the surgical procedure.

Abstract: An ophthalmic endoprobe system comprises an optical fiber configured to transmit light energy along an optical axis. The system further comprises a first scanning element rotatable relative to the optical fiber and arranged to receive at least a portion of the transmitted light energy. The first scanning element includes a diffractive optical element. The system also comprises a second scanning element rotatable relative to the first scanning element and arranged to receive at least a portion of the transmitted light energy from the first scanning element.