Patents by Inventor Michael Papadopoulos
Michael Papadopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124608Abstract: This document relates to methods and materials for treating T cell cancers. For example, a composition containing one or more bispecific molecules targeting T cell receptor £ chain constant region (TRBC) can be administered to a mammal having a T cell cancer to treat the mammal. For example, this document provides methods and materials for using one or more bispecific molecules to treat a mammal having a T cell cancer.Type: ApplicationFiled: February 15, 2022Publication date: April 18, 2024Inventors: Michael S. Hwang, Kenneth W. Kinzler, Brian J. Mog, Nickolas Papadopoulos, Andrew M. Pardoll, Suman Paul, Bert Vogelstein, Shibin Zhou
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Publication number: 20210308291Abstract: A system of fluid sterilization of fluid of vessel is provided, such as sterilization of ballast water for a water vessel. The system incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: ApplicationFiled: December 16, 2019Publication date: October 7, 2021Inventors: Michael Papadopoulos, Christian Papadopoulos, Mark Papadopoulos, James Ray Lewis
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Patent number: 10512701Abstract: A system of fluid sterilization of fluid of vessel is provided, such as sterilization of ballast water for a water vessel. The system incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: GrantFiled: April 11, 2018Date of Patent: December 24, 2019Inventor: Michael Papadopoulos
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Publication number: 20190111166Abstract: A system of fluid sterilization of fluid of vessel is provided, such as sterilization of ballast water for a water vessel. The system incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: ApplicationFiled: April 11, 2018Publication date: April 18, 2019Inventor: Michael Papadopoulos
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Patent number: 10213517Abstract: A system of fluid sterilization is provided, which incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: GrantFiled: July 31, 2017Date of Patent: February 26, 2019Inventor: Michael Papadopoulos
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Publication number: 20180200394Abstract: A system of fluid sterilization is provided, which incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: ApplicationFiled: July 31, 2017Publication date: July 19, 2018Inventor: Michael Papadopoulos
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Patent number: 9757485Abstract: A system and method of fluid sterilization is provided, which incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: GrantFiled: August 26, 2016Date of Patent: September 12, 2017Inventor: Michael Papadopoulos
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Publication number: 20170143858Abstract: A system and method of fluid sterilization is provided, which incorporates a heating section to heat pressurized fluid above prescribed thresholds for temperature, pressure, and duration (e.g., dwell time) to achieve desired levels of sterilization, including a heat exchanger to both (a) preheat fluid prior to entering the heating section and (b) cool outflow of the heating apparatus, in which fluid travels through the apparatus by operating valves forward and aft of the heating section in a controlled sequence to facilitate flow through the system while maintaining prescribed pressure and temperature profiles. The system operates within prescribed ranges of pressure and temperature to achieve the desired level of sterilization without need of maintaining a fixed temperature or a fixed pressure within any portion of the system, including the heating section.Type: ApplicationFiled: August 26, 2016Publication date: May 25, 2017Inventor: Michael Papadopoulos
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Publication number: 20070099927Abstract: The invention relates to compounds of formula (I) wherein A, B, X, R1, R2, G, R3, D and E have the meaning as cited in the description and the claims. Said compounds are useful as coagulants. The invention also relates to the production and use thereof as medicament.Type: ApplicationFiled: October 12, 2004Publication date: May 3, 2007Inventors: Achim Feurer, Sara Bosio, Stephan Bulat, Silvia Cerezo-Galvez, Victor Matassa, Inge Ott, Michael Papadopoulos, Claudia Rosenbaum, Jens Schamberger, Gunther Metz
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Patent number: 7028612Abstract: A plurality of curved plates which are adapted to be mounted on an embossing roll are identically engraved with an embossing pattern that matches the plate dimensions, permitting them to be interchanged or replaced without disrupting pattern discontinuity. In one embodiment, the pattern is created to match a given plate by laying out a skew grid matching plate corners, and using grid parallelograms as pattern unit cells. In another embodiment, an existing doubly periodic pattern is minimally distorted to match the plate geometry.Type: GrantFiled: December 23, 2003Date of Patent: April 18, 2006Assignee: Paper Converting Machine CompanyInventors: Jeremy James Michael Papadopoulos, Lawrence D. Mikulsky, Edward L. Schneider, Karen Jorgensen
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Patent number: 6647879Abstract: A sleeve is provided with a clamp for removably clamping the sleeve on a mandrel. A rigid ring is mounted inside of the sleeve at each end of the sleeve. Each ring has a generally cylindrical inside surface which includes a curved contact portion which extends for less than 180 degrees and which is engageable with the outside surface of the mandrel. A curved clamp arm is pivotally secured at one end thereof to each ring. An eccentric shaft extends through an opening in the other end of the clamp arm. Rotation of the eccentric shaft moves the clamp arm toward the contact portion of the ring so that the mandrel can be clamped between the clamp arm and the contact portion.Type: GrantFiled: December 26, 2002Date of Patent: November 18, 2003Assignee: Paper Converting Machine Co.Inventors: Jeremy James Michael Papadopoulos, Robert W. Braun, Joseph R. Bero
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Publication number: 20020197346Abstract: An embossing roll includes a roll body and a plurality of plates which are removably secured to the roll body. Each plate includes an outer surface which is provided with an embossing pattern. The plates can be secured to the roll body by vacuum and/or mechanical devices.Type: ApplicationFiled: May 22, 2002Publication date: December 26, 2002Inventor: Jeremy James Michael Papadopoulos
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Patent number: 6258044Abstract: A non-lacerational technique to collect cells in an oral mouth cavity utilizes a brush with bristles which have an abrading surface and collect cells from the superficial, intermediate and basal layers of the oral tissue.Type: GrantFiled: July 23, 1999Date of Patent: July 10, 2001Assignee: Oralscan/Trylon Joint VentureInventors: Neal M. Lonky, Jeremy James Michael Papadopoulos
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Patent number: 5430854Abstract: A data processing system having execution units for executing instruction sequences determines at least two conditionals in accordance with the instructions and sets respective flags according to the determined conditionals. These flags are stored and later retrieved sequentially and the execution unit executes selected instructions of the instruction sequence according to the sequentially retrieved mask flags. These masked flags may be stored sequentially in a stack for sequential retrieval at a later time.Type: GrantFiled: October 27, 1993Date of Patent: July 4, 1995Inventors: David L. Sprague, Kevin Harney, Eiichi Kowashi, Michael Keith, Allen H. Simon, Michael Papadopoulos, Walter P. Hays, George F. Salem, Shih-Wei Shiue, Anthony P. Bertapelli, Vitaly H. Shilman
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Patent number: 5361370Abstract: A single-instruction multiple-data video signal processor employs a dual-ported local memory architecture in each local memory including a dedicated port for transfers between the local memory and a global memory. A block transfer controller, in combination with the dedicated port, permit each access to the global memory by a datapath processor to be overlapped with its instruction processing, thus usually avoiding stalling of the video signal processor.Type: GrantFiled: October 24, 1991Date of Patent: November 1, 1994Assignee: Intel CorporationInventors: David L. Sprague, Kevin Harney, Eiichi Kowashi, Michael Keith, Allen H. Simon, Michael Papadopoulos, Walter P. Hays, George F. Salem, Shih-Wei Shiue, Anthony P. Bertapellil, Vitaly H. Shilman
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Patent number: D344462Type: GrantFiled: March 3, 1992Date of Patent: February 22, 1994Assignee: F F Seeley Nominees Pty. Ltd.Inventor: Michael Papadopoulos