Abstract: A medicament delivery device for injecting medicament is described. The device has a body having a proximal end and a distal end, a needle for injecting medicament, an actuation member which is movable relative to the body from a first position to a second position for dispensing medicament from the needle, a lock ring which is rotatable relative to the body from a pre-use position, in which movement of the actuation member from the first position to the second position is prevented, to a use position in which movement of the actuation member from the first position to the second position is permitted and a cap which is removably attached to the medicament delivery device. The cap has a portion which is configured to prevent rotation of the lock ring from the pre-use position to the use position when the cap is attached to the medicament delivery device.

Abstract: A depressurisation valve (100) for a pressurised cooling circuit, comprising a main valve (101), a pilot line (104) fluidically coupled to the inlet (110) and closable by a first control valve (105), the first control valve controlled by pressure at the inlet to open above a low pressure threshold, a valve dome (106) containing a first piston (107) coupled to the main valve, the valve dome being fluidically coupled to the pilot line, wherein in normal operation, pressure on the first piston urges the valve into the closed position, and when the pressure in the coolant circuit is lower than the low pressure threshold, the first control valve closes to allow the main valve to open, when the pressure in the coolant circuit is higher than the high pressure threshold, the second control valve is configured to open and reduce the pressure in the valve dome.

Abstract: A depressurisation valve (100) for a pressurised cooling circuit, comprising a main valve (101), a pilot line (104) fluidically coupled to the inlet (110) and closable by a first control valve (105), the first control valve controlled by pressure at the inlet to open above a low pressure threshold, a valve dome (106) containing a first piston (107) coupled to the main valve, the valve dome being fluidically coupled to the pilot line, wherein in normal operation, pressure on the first piston urges the main valve into the closed position, and when the pressure in the coolant circuit is lower than the low pressure threshold, the first control valve closes to allow the main valve to open, when the pressure in the coolant circuit is higher than the high pressure threshold, a second control valve opens to transmit fluid pressure to apply a second force to the main valve opposing the first force to urge the main valve to the open position.

Abstract: A medicament delivery device comprising: a proximal end and a distal end defining a longitudinal axis; a body; a button arranged at the proximal end and configured to actuate the medicament delivery device; and a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the button is not permitted to move along the longitudinal axis relative to the body, and a second position in which the button is permitted to move along the longitudinal axis relative to the body; wherein movement of the lock ring from the first position towards the second position causes the button to move along the longitudinal axis relative to the body.

Abstract: According to a first aspect of this disclosure, there is described an injection device includes: a body; a needle shroud retractable into the body including a shroud pin; a collar rotatable with respect to the body and including a cam track engageable with the shroud pin. The cam track includes: a first portion configured to, during retraction of the needle shroud into the body, guide the shroud pin from an initial position to a hold position and cause the collar to rotate relative to the body; a second portion configured to, during extension of the needle shroud from the body subsequent to the retraction, guide the shroud pin from the hold position to a final position and cause the collar to further rotate relative to the body; and a non-return surface configured to, subsequent to the extension, prevent further retraction of the needle shroud into the body.

Abstract: A medicament delivery device is described. The medicament delivery device includes a proximal end and a distal end defining a longitudinal axis; a body; and a button arranged at the proximal end and configured to actuate the medicament delivery device. The medicament delivery device further includes a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the button is not permitted to move along the longitudinal axis relative to the body, and a second position in which the button is permitted to move along the longitudinal axis relative to the body; a plurality of first indication elements circumferentially spaced around a first portion of the medicament delivery device; and a plurality of second indication elements circumferentially spaced around a second portion of the medicament delivery device.

Abstract: A medicament delivery device is described.

Abstract: A medicament delivery device for injecting medicament which has a body having a proximal end and a distal end, a needle for injecting medicament and an actuation member which is movable relative to the body. The actuation member is movable from a first position to a second position and movable from the second position to a dispensing position for dispensing medicament from the needle. The second position is proximal of the first position. The medicament delivery device further has a cap which is removably attached to the medicament delivery device. The cap has a portion configured to prevent movement of the actuation member from the first position to the second position when the cap is attached to the medicament delivery device.

Abstract: The application relates to a lock ring for a medicament delivery device. The lock ring comprises a hollow main body formed from a plurality of circumferentially extending portions. Each portion is defined between tool split lines defining circumferential ends of the portions. Each circumferential end of a portion is connected to an adjacent portion along a tool split line. The main body comprises a plurality of bearing elements configured to contact a body of a medicament delivery device. Each of the plurality of bearing elements is configured to form a low friction rotation interface. At least one of the plurality of bearing elements is formed proximate to one of the circumferential ends of a portion of the main body.

Abstract: According to a first aspect of this disclosure, there is described an injection device includes: a body; a needle shroud retractable into the body including a shroud pin; a collar rotatable with respect to the body and including a cam track engageable with the shroud pin. The cam track includes: a first portion configured to, during retraction of the needle shroud into the body, guide the shroud pin from an initial position to a hold position and cause the collar to rotate relative to the body; a second portion configured to, during extension of the needle shroud from the body subsequent to the retraction, guide the shroud pin from the hold position to a final position and cause the collar to further rotate relative to the body; and a non-return surface configured to, subsequent to the extension, prevent further retraction of the needle shroud into the body.

Abstract: An injection device comprises: an injection device body; a needle shroud comprising a shroud pin; and a collar rotatable with respect to the injection device body and comprising a cam track. During retraction of the needle shroud, a first portion of the cam track guides the shroud pin to a hold position and cause the collar to rotate relative to the injection device body from a first position to a second position. During a subsequent extension of the needle shroud, a second portion of the cam track guides the shroud pin from the hold position to a final position and causes the collar to further rotate relative to the injection device body from the second position to a third position, the second portion comprising a blocking portion configured to prevent extension of the needle shroud from the injection device body when the collar is held in the second position.

Abstract: An injection device comprises: an injection device body; a needle shroud comprising a shroud pin; and a collar rotatable with respect to the injection device body and comprising a cam track. During retraction of the needle shroud, a first portion of the cam track guides the shroud pin to a hold position and cause the collar to rotate relative to the injection device body from a first position to a second position. During a subsequent extension of the needle shroud, a second portion of the cam track guides the shroud pin from the hold position to a final position and causes the collar to further rotate relative to the injection device body from the second position to a third position, the second portion comprising a blocking portion configured to prevent extension of the needle shroud from the injection device body when the collar is held in the second position.

Abstract: A damping device for a medicament delivery device, comprising: a generally cylindrical first collar; a housing comprising a generally annular cavity configured to receive at least a portion of the first collar; wherein the first collar is configured to be rotatable relative to the housing about a central longitudinal axis of the damping device, and wherein the cavity is configured to contain a fluid for impeding rotational movement of the first collar relative to the housing; and a sealing arrangement configured to fluidly seal an interface between the housing and the first collar.

Abstract: A medicament delivery device includes a needle disposed at a distal end of the medicament delivery device, a body for a syringe, and a needle cover axially movable relative to the body between an extended position in which the needle cover covers the needle and a retracted position for dispensing medicament from the medicament delivery device. The needle protruding from the distal end of the needle cover when the needle cover is in the retracted position. The medicament delivery device includes an actuation member configured to be movable from an initial position to an engaged position such that when the actuation member is in its initial position, the needle cover can be axially moved between its retracted position and its extended position, and when the actuation member is in its engaged position, the actuation member engages with the needle cover to hold the needle cover in its retracted position.

Abstract: An online concierge system generates a plurality of bundles based in part on a seed list of contexts by generating one or more prompts that are provided to a machine learned model, where for a first context of the seed list of contexts, a prompt instructs the machine learned model to determine: a first bundle for the given context, where the first bundle includes a list of products, a title, and an explanation. The plurality of bundles is stored in a datastore. The system selects, for a customer, the first bundle from the plurality of bundles in the datastore, and generates a list of items from an online catalog that corresponds to the list of products of the first bundle. The system provides the list of items, the title, and the explanation for presentation to a customer client device of the customer.

Abstract: A medicament delivery device comprising a body, a needle, and an actuation member movable proximally from an initial position to a protruded position, and distally from the protruded position to an actuation position. The device has a transfer member which is movable proximally between an extended and a retracted position. In the extended position the distal end of the transfer member protrudes from the body. One of the actuation member and the transfer member has a drive slot and the other of the actuation member and the transfer member comprises a protrusion located in the drive slot. The drive slot has a circumferentially-extending portion having an abutment surface. The protrusion engages the abutment surface to move the actuation member from the initial position to the protruded position.

Abstract: A medicament delivery device includes a first component, a second component configured to be movable with respect to the first component, and a temperature-dependent interconnect configured to resist movement of the first component relative to the second component. The temperature-dependent interconnect includes an engagement member and a temperature-dependent material configured to engage each other. The temperature-dependent material has a temperature-dependent material characteristic such that the temperature-dependent material has (i) a first material characteristic at a first temperature of the temperature-dependent material to resist movement of the first component with respect to the second component, and (ii) a second material characteristic at a second temperature of the temperature-dependent material to allow movement of the first component with respect to the second component.

Abstract: A medicament delivery device includes a needle being axially moveable from a retracted position to an exposed position. The device includes an actuation member configured to be movable to an actuation position to cause the needle to move from the retracted position to the exposed position. The device includes a locking member for preventing the movement of the actuation member to the actuation position, and a locking release member being axially moveable towards a proximal end of the medicament delivery device from a first position, in which the locking member is prevented from moving to a release position in which the actuation member is released for the movement of the actuation member to the actuation position, to a second position, in which the locking member is free to move to the release position in which the actuation member is released for the movement of the actuation member to the actuation position.

Abstract: A medicament delivery device includes an actuator including an actuation member configured to be movable by a user to an actuation position to cause a dose of medicament to be dispensed from the medicament delivery device. The actuator is configured to be movable from a deactivated position in which a user is prevented from moving the actuation member to the actuation position to an activated position in which the actuation member is released for movement by a user to the actuation position. The device includes a temperature-dependent actuator configured to move the actuator from the deactivated position to the activated position in response to a change in temperature of the temperature-dependent actuator.

Abstract: A medicament delivery device has an actuation member which is movable relative to a body. The actuation member has a flexible arm comprising an engagement surface. The device has a contoured surface. When the actuation member is in a first position the engagement surface engages the contoured surface. When the actuation member moves to a second position, the flexible arm is deflected radially by the engagement of the engagement surface with the contoured surface. The device further has a blocking member. The blocking member has a proximal portion which engages the flexible arm when the blocking member is in an extended position for preventing the flexible arm from being deflected radially and moving distally. The blocking member is movable relative to the body to disengage the proximal portion from the flexible arm.