Patents by Inventor Michael Patane

Michael Patane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-DEAZAPURINE MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF
    Publication number: 20160251390
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Application
    Filed: September 28, 2015
    Publication date: September 1, 2016
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE
    Publication number: 20160235716
    Abstract: Compounds having a structure of Formula (IX): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b, R3a, R3b, R4a, R4b, Q1- - - -Q2, R6, R7, A, B, W, x, and y are as defined herein and are provided. Pharmaceutical compositions comprising such compounds and methods for treating various HAT-related conditions or diseases, including cancer, by administration of such compounds are also provided.
    Type: Application
    Filed: September 17, 2015
    Publication date: August 18, 2016
    Applicant: ABBVIE INC.
    Inventors: Edward A. Kesicki, Arthur F. Kluge, Michael A. Patane, John H. Van Drie, JR., Ce Wang, Maricel Torrent, Michael L. Curtin, Todd M. Hansen, Rick F. Clark, Robin R. Frey, Zhiqin Ji, Yujia Dai, William J. McClellan, Jane Gong, Gui-dong G. Zhu, Anthony Mastracchio, Michael R. Michaelides, Thomas D. Penning, Chunqiu C. Lai
  • Compositions and methods for treating or preventing diseases or disorders associated with misregulated EIF4E
    Patent number: 9409901
    Abstract: Disclosed herein are compounds, compositions, formulations, kits and methods of treatment useful for treating or preventing one or more hyperproliferative disorders, e.g., cancer or a neurological disease or disorder.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: August 9, 2016
    Assignee: Bantam Pharmaceutical, LLC
    Inventor: Michael Patane
  • Modulators of Histone Methyltransferase, and Methods of Use Thereof
    Publication number: 20160068559
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, and the uses of the compounds and compositions as modulators of histone methyltransferases, and for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Application
    Filed: April 7, 2015
    Publication date: March 10, 2016
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • COPOLYMERS OF STARCH AND CELLULOSE
    Publication number: 20150299957
    Abstract: Copolymers comprising cellulose and starch connected by at least one cross-linker, methods of producing the copolymers, and formed articles comprising the copolymers are described herein. The copolymers may be biodegradable and may have improved physical properties when compared to the homopolymers and other biodegradable polymers. In some embodiments, the copolymer may be more flexible than unmodified cellulose may have better structural integrity than unmodified starch.
    Type: Application
    Filed: November 6, 2012
    Publication date: October 22, 2015
    Inventor: Michael PATANE
  • Delivery of corticosteroids through iontophoresis
    Patent number: 9149525
    Abstract: Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: October 6, 2015
    Assignee: EyeGate Pharmaceuticals, Inc.
    Inventors: Mike Jaffe, Gary Cook, Perry Calias, Michael A. Patane
  • Compositions And Methods For Treating Or Preventing Diseases Or Disorders Associated With Misregulated EIF4E
    Publication number: 20150274717
    Abstract: Disclosed herein are compounds, compositions, formulations, kits and methods of treatment useful for treating or preventing one or more hyperproliferative disorders, e.g., cancer or a neurological disease or disorder.
    Type: Application
    Filed: October 22, 2013
    Publication date: October 1, 2015
    Inventor: Michael Patane
  • 7-deazapurine modulators of histone methyltransferase, and methods of use thereof
    Patent number: 9145438
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: September 29, 2015
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Kevin W. Kuntz, Edward J. Olhava, Michael A. Patane
  • Modulators of histone methyltransferase, and methods of use thereof
    Patent number: 9029343
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, and the uses of the compounds and compositions as modulators of histone methyltransferases, and for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: May 12, 2015
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Kevin W. Kuntz, Edward J. Olhava, Michael A. Patane
  • AMINOTHIAZOLES AND THEIR USES
    Publication number: 20140315790
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases.
    Type: Application
    Filed: April 17, 2013
    Publication date: October 23, 2014
    Inventors: Simon Bushell, Matthew J, LaMarche, Michael A. Patane, Lewis Whitehead
  • 7-deazapurine modulators of histone methyltransferase, and methods of use thereof
    Patent number: 8722877
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Grant
    Filed: September 4, 2013
    Date of Patent: May 13, 2014
    Assignee: Epizyme, Inc.
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • 7-Deazapurine Modulators of Histone Methyltransferase, and Methods of Use Thereof
    Publication number: 20140073597
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 13, 2014
    Applicant: EPIZYME, INC.
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • DELIVERY OF CORTICOSTEROIDS THROUGH IONTOPHORESIS
    Publication number: 20140046242
    Abstract: Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof.
    Type: Application
    Filed: October 22, 2013
    Publication date: February 13, 2014
    Inventors: Mike Jaffe, Gary Cook, Perry Calias, Michael A. Patane
  • Modulators of Histone Methyltransferase, and Methods of Use Thereof
    Publication number: 20130310333
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, and the uses of the compounds and compositions as modulators of histone methyltransferases, and for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Application
    Filed: December 5, 2011
    Publication date: November 21, 2013
    Applicant: EPIZYME, INC.
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • 7-Deazapurine Modulators of Histone Methyltransferase, and Methods of Use Thereof
    Publication number: 20130310334
    Abstract: Disclosed are compounds, pharmaceutical compositions containing the compounds, uses of the compounds and compositions as modulators of histone methyltransferases, and methods for treating diseases influenced by modulation of histone methyltransferase activity.
    Type: Application
    Filed: December 5, 2011
    Publication date: November 21, 2013
    Applicant: EPIZYME, INC.
    Inventors: Richard Chesworth, Kevin Wayne Kuntz, Edward James Olhava, Michael A. Patane
  • Organic compounds and their uses
    Patent number: 8445527
    Abstract: The present invention provides a method of treating a HCV infection in a subject in need thereof by administering a compound of Formula I: or pharmaceutically acceptable salts thereof or stereoisomers thereof.
    Type: Grant
    Filed: May 22, 2012
    Date of Patent: May 21, 2013
    Assignee: Novartis AG
    Inventors: Michael Patane, Prakash Raman, David Thomas Parker, Jiping Fu, Branko Radetich, Mohindra Seepersaud, Aregahegn Yifru, Rui Zheng, Trixi Brandl, Francois Lenoir, Pascal Rigollier, Oliver Simic
  • Delivery Of Corticosteroids Through Iontophoresis
    Publication number: 20120283231
    Abstract: Disclosed herein are formulations of dexamethasone or a prodrug thereof suitable for delivery by ocular iontophoresis and methods of use thereof.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 8, 2012
    Applicant: EYEGATE PHARMACEUTICALS, INC.
    Inventors: Mike Jaffe, Gary Cook, Perry Calias, Michael A. Patane
  • ORGANIC COMPOUNDS AND THEIR USES
    Publication number: 20120231998
    Abstract: The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
    Type: Application
    Filed: May 22, 2012
    Publication date: September 13, 2012
    Inventors: Trixi Brandl, Jiping Fu, Francois Lenoir, David Thomas Parker, Michael Patane, Branko Radetich, Prakash Raman, Pascal Rigollier, Mohindra Seepersaud, Oliver Simic, Aregahegn Yifru, Rui Zheng
  • OCULAR IONTOPHORESIS OF CHARGED MICELLES CONTAINING BIOACTIVE AGENTS
    Publication number: 20120225834
    Abstract: This invention is related to pharmaceutical compositions consisting of charged micelles containing bioactive agents. The invention is also related to the methods of delivery of charged micelles to the eye of a mammal by iontophoresis.
    Type: Application
    Filed: September 29, 2010
    Publication date: September 6, 2012
    Applicant: EYEGATE PHARMACEUTICALS, INC.
    Inventors: Peyman Moslemy, Hong Wang, Michael Patane
  • LACTAM COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS
    Publication number: 20120178739
    Abstract: The present invention provides novel compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: March 14, 2012
    Publication date: July 12, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Christopher Blackburn, Christopher F. Claiborne, Courtney A. Cullis, Natalie A. Dales, Michael Patane, Matthew Stirling, Omar Stradella, Gabriel S. Weatherhead