Abstract: Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia, as defined in the specification. In an embodiment, a pharmaceutical composition can be in a liquid dosage form and can comprise a therapeutically effective amount of the compound or a pharmaceutically acceptable salt thereof as an adjuvant and a therapeutic agent. In another embodiment, a method of adjuvant treating a disorder or condition can comprising administering the pharmaceutical composition to a patient.

Abstract: A user request to select a rival to play against asynchronously for an event is received. In response to the user request, a rival selector user interface is displayed. The rival selector UI includes an identification of one or more users that can be selected and one or more filter criteria that can be selected to change which users are identified in the rival selector UI. The user selects one of the identified users that is used as the rival to play against asynchronously for the event. Game data for the rival for the event is obtained, the game data including both a performance of the rival in the event and data indicating a manner in which an object of the rival is customized by the rival. While the user is playing the event, the object as customized by the rival is played back based on the performance data.