Abstract: Methods for selecting transgenic cells comprising two or more drug resistance genes with a combination of cytotoxic drugs (e.g., trimetrexate (TMTX) and hydroxyurea (HU)). Such selection can be completed in vitro or in vivo. Transgenic cells and vectors comprising combinations of resistance genes are also provided. Transgenic cells of the embodiments can be used as cell based therapeutics, such as for treatment of HIV infection.

Abstract: A system and methods for pumping a multiphase fluid using a pneumatic pump are described herein. The method includes separating a multiphase fluid into a gas stream and liquid streams, and flowing a liquid stream into a pressure vessel of a pneumatic pump until a liquid level within the pressure vessel reaches a specified high level. The method also includes compressing the gas stream to form a high-pressure gas and pressurizing the pressure vessel by the flowing high-pressure gas into the pressure vessel until a pressure level within the pressure vessel reaches a specified high level. The method further includes pumping the liquid stream from the pressure vessel to a destination until the liquid level within the pressure vessel drops to a specified low level, wherein the high-pressure gas provides a motive force for pumping the liquid stream.

Abstract: A controller for a battery charger that includes a power converter has parametric sensors for providing a sensed Vin signal, a sensed Vout signal and a sensed Iout signal. A battery current regulator (BCR) is coupled to receive the sensed Iout signal and an Iout reference, and outputs a first duty cycle control signal. An input voltage regulator (IVR) receives the sensed Vin signal and a Vin reference. The IVR provides a second duty cycle control signal. A processor receives the sensed Iout signal and utilizes a Maximum Power Point Tracking (MPPT) algorithm, and provides the Vin reference to the IVR. A selection block forwards one of the first and second duty cycle control signals as a duty cycle control signal to the power converter. Dynamic switching between the first and second duty cycle control signals maximizes the power delivered to the battery.

Abstract: Method, apparatus and systems for a quick change lamp ballast assembly for newly manufactured lamp fixtures having the quick change ballast or a retrofit for an existing lamp fixture. The quick change ballast assembly includes a ballast mounting fixture 110 for housing the ballast 300, a wire connector fixture 130 and a mounting plate 120 for mounting the ballast mounting fixture 110. The ballast assembly allows for replacement of a non operating ballast to reduce replacement time and labor costs. In a new lamp fixture, the quick change ballast is thermally isolated from the lamp fixture, which reduces the effects of the waste heat from the ballast, and increase overall building efficiency by reducing the cooling load.

Abstract: The present invention provides a method of forming coatings of at least two different coating molecules on at least two electrodes, the method comprising: (a) providing an array of at least two individually-addressable electrodes, (b) allowing a layer of a masking molecule to adsorb onto all electrodes, (c) inducing electrochemical desorption of the masking molecule from at least one but not all electrodes to expose a first set of exposed electrodes, (d) allowing a first coating molecule to adsorb onto the first set of exposed electrodes, (e) exposing all electrodes to a masking molecule to allow adsorption of the masking molecule onto all electrodes, (f) inducing electrochemical desorption of masking molecule from a second set of electrodes to expose a second set of exposed electrodes, (g) allowing a second coating molecule to adsorb onto the second set of exposed electrodes.

Abstract: Method, apparatus and systems for a quick change lamp ballast assembly for newly manufactured lamp fixtures having the quick change ballast or a retrofit for an existing lamp fixture. The quick change ballast assembly includes a ballast mounting fixture 110 for housing the ballast 300, a wire connector fixture 130 and a mounting plate 120 for mounting the ballast mounting fixture 110. The ballast assembly allows for replacement of a non operating ballast to reduce replacement time and labor costs. In a new lamp fixture, the quick change ballast is thermally isolated from the lamp fixture, which reduces the effects of the waste heat from the ballast, and increase overall building efficiency by reducing the cooling load.

Abstract: A sensor comprises a reference sample arranged to be subject to at least one variable physical parameter such that a variation in the value of the at least one variable physical parameter causes a change in the magnetisation of the reference sample, means for measuring the magnetisation of the reference sample, and means for determining in dependence upon the measured magnetisation whether there has been a variation in the value of the at least one variable physical parameter, wherein the reference sample comprises a Heusler alloy.

Abstract: Method for modulating the migration of neural progenitor cells in a mammal by exposing the cells to a VEGFR-2 ligand and FGF-2. Methods of treating neurological disorders by exposing the mammal to a VEGFR-2 ligand in the presence of FGF-2 are also provided. A composition including a biocompatible matrix associated with FGF-2 is also provided.

Abstract: A sensor comprises a reference sample arranged to be subject to at least one variable physical parameter such that a variation in the value of the at least one variable physical parameter causes a change in the magnetisation of the reference sample, means for measuring the magnetisation of the reference sample, and means for determining in dependence upon the measured magnetisation whether there has been a variation in the value of the at least one variable physical parameter, wherein the reference sample comprises a Heusler alloy.

Abstract: An astragal boot is mounted onto a lower end of an astragal disposed on a free end of a semi-active door in a double-door set disposed over a threshold. The astragal boot includes a platform and a pair of lateral fins spaced from one another and being flexible and projecting downwardly from the platform to seal against the threshold. Primary fins are flexible and project downwardly from the platform a greater distance than the lateral fins and are joined to and extend between the lateral fins. The lateral fins are joined to the primary fins and hold the primary fins into sealing engagement with the threshold to prevent the penetration of water between the astragal boot and the threshold. The lateral fins hold the primary fins against the threshold because the primary fins are thinner thereby minimizing the effort required to close the semi-active door over the threshold.

Abstract: The present invention provides a method of forming coatings of at least two different coating molecules on at least two electrodes, the method comprising: (a) providing an array of at least two individually-addressable electrodes, (b) allowing a layer of a masking molecule to adsorb onto all electrodes, (c) inducing electrochemical desorption of the masking molecule from at least one but not all electrodes to expose a first set of exposed electrodes, (d) allowing a first coating molecule to adsorb onto the first set of exposed electrodes, (e) exposing all electrodes to a masking molecule to allow adsorption of the masking molecule onto all electrodes, (f) inducing electrochemical desorption of masking molecule from a second set of electrodes to expose a second set of exposed electrodes, (g) allowing a second coating molecule to adsorb onto the second set of exposed electrodes.

Abstract: An astragal boot is mounted onto a lower end of an astragal disposed on a free end of a semi-active door in a double-door set disposed over a threshold. The astragal boot includes a platform and a pair of lateral fins spaced from one another and being flexible and projecting downwardly from the platform to seal against the threshold. Primary fins are flexible and project downwardly from the platform a greater distance than the lateral fins and are joined to and extend between the lateral fins. The lateral fins are joined to the primary fins and hold the primary fins into sealing engagement with the threshold to prevent the penetration of water between the astragal boot and the threshold. The lateral fins hold the primary fins against the threshold because the primary fins are thinner thereby minimizing the effort required to close the semi-active door over the threshold.

Abstract: A threshold assembly includes a base defining a channel, a plurality of nuts slideably engaged in the channel, a rail disposed on the base and defining a plurality of holes, and a plurality of threaded fasteners rotationally retained in the holes and threadedly engaging the nuts. The channel has a neck and a pair of opposing sides angling outwardly from the neck into the base. Each nut presents opposing contact surfaces complimentary to the opposing sides of the channel such that the nut is slideably engaged in the channel. The nut also includes an elongated platform such that when the threaded fastener is rotated, the elongated platform and the opposing contact surfaces of the nut engage the opposing sides of the channel such that the height of the rail relative to the base is adjusted in response to rotation of the threaded fastener relative to the nut.

Abstract: A representative data storage medium includes: a substrate; and a plurality of elongate, carrier molecules anchored to the substrate. Each carrier molecule carries one or more luminescent groups and is alterable between a readable conformation in which the luminescent groups carried by the molecule are able to emit radiation and an inactive conformation in which the luminescent groups carried by the molecule are inhibited from emitting radiation. A writer to and reader of the data storage medium are also disclosed.

Abstract: A data storage device comprising a planar integrated circuit (13) formed on a face of a body of an electronic storage material which provides a plurality of spaced discrete columns of spaced discrete electric charge storage sites (5), the columns extending in directions normal to the plane of the intergrated circuit and the integrated circuit providing access to the storage sites.

Abstract: A method of testing a field effect device for radiation hardness. The method comprises the steps of subjecting the field effect device to a low temperature environment, developing a first set of data points by measuring the conductance of the field effect device as a function of gate voltage at a first substrate bias, developing a second set of data points by measuring the conductance of the field effect device as a function of gate voltage at a second substrate bias, which is different from the first substrate bias, and comparing the first and second sets of data points to obtain an assessment of radiation hardness.