Abstract: The invention provides methods and compositions for treating a muscular dystrophy, e.g., Duchenne muscular dystrophy (DMD), in a subject, with a fatty acid acetylated salicylate, e.g., edasalonexent, effective to achieve a threshold plasma concentration of the fatty acid acetylated salicylate in the subject, e.g., a threshold plasma concentration of at least about 20 ng/ml for least 12 hours in a 24 hour period.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid associated with a dispenser assembly is cooperatively disposed relative to an activating assembly. The activating assembly is operated in moveable engagement with the head portion, and activates the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from. At least one disinfectant agent is dispersed within or comprises a portion of the housing and is formulated to be destructively effective against pathogenic bacteria, such as in the spore form, which is generally not affected by the cleaning fluid.

Abstract: An assembly structured to restrict contamination of individuals from association with the heads of stethoscope comprising a housing including a path of travel along which the head portion passes. Different embodiments include the dispensing of cleaning fluid or the delivery of protective barriers onto predetermined portions of the stethoscope heads, while passing along the path of travel. A dispenser assembly and a cooperatively disposed activating assembly are manually operated by moveable, driving engagement with the head portion passing through the housing. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by a head passing along the path of travel. Differently structured dispenser assemblies function to either deliver the cleaning fluid or individually dispense the barriers onto different heads, so as to either facilitate the cleaning or protective covering of exposed surfaces of the stethoscope heads, dependent on the embodiment utilized.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid associated with a dispenser assembly is cooperatively disposed relative to an activating assembly. The activating assembly is operated in moveable engagement with the head portion, and activates the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from. At least one disinfectant agent is dispersed within or comprises a portion of the housing and is formulated to be destructively effective against pathogenic bacteria, such as in the spore form, which is generally not affected by the cleaning fluid.

Abstract: An assembly structured to restrict contamination of individuals from association with the heads of stethoscope comprising a housing including a path of travel along which the head portion passes. Different embodiments include the dispensing of cleaning fluid or the delivery of protective barriers onto predetermined portions of the stethoscope heads, while passing along the path of travel. A dispenser assembly and a cooperatively disposed activating assembly are manually operated by moveable, driving engagement with the head portion passing through the housing. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by a head passing along the path of travel. Differently structured dispenser assemblies function to either deliver the cleaning fluid or individually dispense the barriers onto different heads, so as to either facilitate the cleaning or protective covering of exposed surfaces of the stethoscope heads, dependent on the embodiment utilized.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid associated with a dispenser assembly is cooperatively disposed relative to an activating assembly. The activating assembly is operated in moveable engagement with the head portion, and activates the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from. At least one disinfectant agent is dispersed within or comprises a portion of the housing and is formulated to be destructively effective against pathogenic bacteria, such as in the spore form, which is generally not affected by the cleaning fluid.

Abstract: An assembly structured to restrict contamination of individuals from association with the heads of stethoscope comprising a housing including a path of travel along which the head portion passes. Different embodiments include the dispensing of cleaning fluid or the delivery of protective barriers onto predetermined portions of the stethoscope heads, while passing along the path of travel. A dispenser assembly and a cooperatively disposed activating assembly are manually operated by moveable, driving engagement with the head portion passing through the housing. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by a head passing along the path of travel. Differently structured dispenser assemblies function to either deliver the cleaning fluid or individually dispense the barriers onto different heads, so as to either facilitate the cleaning or protective covering of exposed surfaces of the stethoscope heads, dependent on the embodiment utilized.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispenser assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: The present invention is directed, in various embodiments, to a computer system comprising a party database and a products-role database. The party database contains party data records that contain information about various parties, respectively. The products-role database contains a number of product-role records. Each of the product-role records is associated with a different financial product. Further, each of the product-role records contains a unique party identifier for each party that performs a role for the corresponding financial product (such as issuer, guarantor, custodian, etc.) and a corresponding link to a party data record in the party database for each party, The party identifier is used consistently throughout the records of the products-role database to identify the corresponding party for all products where the party performs a role.

Abstract: An assembly structured to restrict contamination of individuals from association with the heads of stethoscope comprising a housing including a path of travel along which the head portion passes. Different embodiments include the dispensing of cleaning fluid or the delivery of protective barriers onto predetermined portions of the stethoscope heads, while passing along the path of travel. A dispenser assembly and a cooperatively disposed activating assembly are manually operated by moveable, driving engagement with the head portion passing through the housing. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by a head passing along the path of travel. Differently structured dispenser assemblies function to either deliver the cleaning fluid or individually dispense the barriers onto different heads, so as to either facilitate the cleaning or protective covering of exposed surfaces of the stethoscope heads, dependent on the embodiment utilized.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispenser assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispenser assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispenser assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispensing assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispensing assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispensing assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispensing assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: An assembly structured to clean the head portion of a stethoscope comprising a housing including a path of travel along which the head portion passes during cleaning. A supply of cleaning fluid is associated with a dispensing assembly which is cooperatively disposed relative to an activating assembly. The activating assembly is manually operated due to moveable engagement with the head portion as it travels along the path of travel. The activating assembly is thereby operatively positioned to activate the dispenser assembly when engaged by the head portion as it passes along the path of travel. The dispensing assembly delivers the cleaning fluid to an applicator assembly which distributes the cleaning fluid to the head portion and facilitates the cleaning thereof and removal of excess cleaning fluid there from.

Abstract: A pharmaceutical composition comprises a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer and a lipophilic microphase-forming material. Alternatively, a solid amorphous dispersion comprising a low-solubility drug and a concentration-enhancing polymer is co-administered with a lipophilic microphase-forming material to an in vivo use environment.

Abstract: CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are self-emulsifying or self-microemulsifying, and comprise 1. a CETP inhibitor; 2. a cosolvent; 3. a surfactant having an HLB of 1 to 8; 4. a surfactant having an HLB of over 8 to 20; and 5. optionally, a digestible oil.