Abstract: Provided is an expandable surgical access port having an arm mounting body defining an opening surrounding a longitudinal axis, a number of primary arms arranged around the longitudinal axis, a number of secondary arms arranged around the longitudinal axis, an activation ring rotatably mounted to the arm mounting body to pivot the primary and secondary arms from a closed position to an opened position, and a an expandable membrane extending along the primary and secondary arms. When arms are in the opened position, the expandable membrane has an elongated membrane cross-section as viewed along the longitudinal axis.

Abstract: An inventory system comprised of a central computing device in communication with one or more remote computing devices is disclosed. The central computing device is configured to update inventory information for inventory items held within the inventory system based on information received from the remote computing devices. The remote computing devices are configured to transmit updated inventory information to the central computing devices when an inventory item is newly added to the inventory system and when an inventory item is taken out of the inventory system. The remote computing devices also correspond to one or more inventory units for storing the inventory items. The remote computing devices are configured to transmit order requests to the central computing device that request additional inventory items for their corresponding inventory units.

Abstract: An inventory system comprised of a central computing device in communication with one or more remote computing devices is disclosed. The central computing device is configured to update inventory information for inventory items held within the inventory system based on information received from the remote computing devices. The remote computing devices are configured to transmit updated inventory information to the central computing devices when an inventory item is newly added to the inventory system and when an inventory item is taken out of the inventory system. The remote computing devices also correspond to one or more inventory units for storing the inventory items. The remote computing devices are configured to transmit order requests to the central computing device that request additional inventory items for their corresponding inventory units.

Abstract: Compositions, targeting reagents, modified cells, nucleic acid molecules, systems, and methods for identifying and selecting genomic safe harbor sites for transgene insertion and other genome engineering applications. These materials and methods can be used to develop desired genome engineering applications, such as transgene insertion and expression or genome modification, that take into account the application-specific needs for safety, functional silence, and accessibility and other factors that vary with a desired application's goals and target population. Representative examples of desired genome engineering applications include, but are not limited to, transgene insertion, such as therapeutic transgene insertion, functional gene editing, gene or chromosomal location-specific structural modification, cell marking, gene activation, and/or gene repression.

Abstract: An inventory system comprised of a central computing device in communication with one or more remote computing devices is disclosed. The central computing device is configured to update inventory information for inventory items held within the inventory system based on information received from the remote computing devices. The remote computing devices are configured to transmit updated inventory information to the central computing devices when an inventory item is newly added to the inventory system and when an inventory item is taken out of the inventory system. The remote computing devices also correspond to one or more inventory units for storing the inventory items. The remote computing devices are configured to transmit order requests to the central computing device that request additional inventory items for their corresponding inventory units.

Abstract: This invention provides novel cyclooxygenase-2 selective agents that are particularly useful as imaging probes in non-invasive imaging techniques, such as PET and SPECT. Preferred cyclooxygenase-2 selective agents inhibit cyclooxygenase-2 activity with greater potency and specificity than conventional cyclooxygenase-2 inhibitors. Other aspects of the invention include pharmaceutical compositions including the cyclooxygenase-2 selective agents as well as methods for detecting and/or inhibiting cyclooxygenase-2. These methods are particularly useful for diagnosing and treating disorders, such as inflammation, which is characterized by elevated cyclooxygenase-2 levels.

Abstract: A method for controlling data transfers through a computer system is provided. First information is transferred to a first node of the computer system regarding availability of a first data storage area within a second node of the computer system for data to be transferred through the second node. Also transferred to the first node is second information regarding availability of a second data storage area within the second node for data to be consumed within the second node. The first information and the second information are then processed to determine if data within the first node destined for the second node is to be transferred to the second node.

Abstract: A method for employing an interconnection fabric of a computer system including a first endnode and a second endnode is provided. A first transaction is transferred from the first endnode toward the second endnode over a primary path of the fabric. The first transaction is retransferred from the first endnode toward the second endnode over an alternate path of the fabric after a period of time after transferring the first transaction. An acknowledgement of the first transaction being received by the second endnode over the primary path is transferred to the first endnode after retransferring the first transaction. A second transaction from the first endnode toward the second endnode is transferred solely over the primary path after the acknowledgement is received by the first endnode.