Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: A method of forming a multipack of a plurality of containers includes a label on each container of the plurality of containers. The label at least partially surrounds a portion of each container of the plurality of containers. The method includes assembling the plurality of container into a multipack, heating an area of the multipack that includes the label, and forming an adhesive bond on the heated area of the label on each container. Each container is secured to at least one other container by the adhesive bond.

Abstract: The present disclosure provides methods related to the purification of a biologic. In particular, the present disclosure methods for purifying a biologic using a multifunctional chromatography medium comprising porous beads or particles having a defined pore diameter distribution and one or more ligands conjugated to the surface of the pores capable of removing process-related impurities and product-related impurities from a target biologic.

Abstract: A method for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding is disclosed.

Abstract: A gait belt for lifting and transferring patients including a generally elongated, wide belt body with two free ends, a belt strap connected to the belt body to secure the belt to the patient's waist, belt strap extensions configurable as both a belt body closure and as thigh supports, and multiple lifting handles affixed to the belt.

Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: Methods and Kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Assays that do not require the cyclic transfer of information between a coding tag and a recording tag are also disclosed, including single cycle assays.

Abstract: A method performed by a data system includes automatically learning relationship(s) among datasets based on one or more of a user query or an observation of a data flow through the data system. The method further includes generating an optimized data structure based on the learned relationships among the datasets. The data system then modifies a query plan to obtain query results that satisfy a query by reading the optimized data structure in lieu of reading the datasets.

Abstract: An air conditioner unit may include a bulkhead defining an indoor portion and an outdoor portion, a vent aperture defined in the bulkhead, and a fan assembly for urging a flow of make-up air from the outdoor portion through the vent aperture to the indoor portion. The fan assembly includes a fan housing having two clamshell upper and lower portions that collectively define a fan slot, an arcuate filter slot, and a make-up air duct in fluid communication with the vent aperture. An auxiliary fan is positioned within the fan slot of the fan housing an air filter is positioned within the filter slot.

Abstract: Systems and methods are provided that may be implemented to orchestrate trusted enrollment of an endpoint client information handling system by deploying a signed payload of an enrollment package to the endpoint client system, and by using a client software agent executing on the endpoint client system to first verify the distribution chain and/or signature of the deployed enrollment package before proceeding to use other information contained in the enrollment package to contact a registration server to enroll the endpoint client system.

Abstract: A retractable cable assembly in use with an electrical charger, power adapter, or other power supply. A cable wound on a spool disposed within a housing may be extracted by manually pulling on the cable or pressing of a release switch until the desired length of the cable is drawn. As the cable is drawn an engaged locking mechanism is used to keep the cable in place during and after extraction of the cable until which time retraction of the cable is desired. A retraction actuator disengages the locking mechanism, thereby freeing the cable and immediately retracting the cable within the housing.

Abstract: A method for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding is disclosed.

Abstract: Aspects of the invention provide a process for detecting sources of wireless data packets exhibiting defined behaviour of interest in a wireless network environment, the process comprising the steps of: monitoring the wireless network environment to receive wireless data packets; populating one or more queues of wireless data packets from the received wireless data packets, wherein wireless data packets received are added to the one or more queues dependent on a detection template to detect one or more devices which are sources of one or more of the received wireless data packets, wherein a detection template comprises code defining one or more algorithms applied to the received packets to define the behaviour of interest, extracting device identifier data from the wireless data packets in the queue to identify one or more detected source devices exhibiting said defined behaviour; generating display data carrying information on a signal strength of wireless data packets from the same of the one or more identi

Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: An air conditioner unit including a cabinet having a bulkhead mounted within the cabinet to define an indoor portion and an outdoor portion. A refrigeration loop includes an outdoor heat exchanger positioned within the outdoor portion and an indoor heat exchanger positioned within the indoor portion. A compressor is operably coupled to the refrigeration loop and is configured for urging a flow of refrigerant through the outdoor heat exchanger and the indoor heat exchanger. A makeup air duct extends in fluid communication to the indoor portion of the cabinet. The makeup air duct includes a body and a transition portion in which the body and the transition portion are formed of a polymer foam material.

Abstract: An air conditioner unit is provided including a cabinet. The cabinet includes a front opening including an upper portion and a lower portion each forming a portion of a perimeter of the front opening. The lower portion includes a lower face. A lower handle extends from the lower portion at the lower face. A bulkhead is mounted within the cabinet to form an indoor portion and an outdoor portion. A refrigeration loop includes an outdoor heat exchanger positioned within the outdoor portion and an indoor heat exchanger positioned within the indoor portion. A compressor is operably coupled to the refrigeration loop and is configured for urging a flow of refrigerant through the outdoor heat exchanger and the indoor heat exchanger.

Abstract: Methods and Kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Assays that do not require the cyclic transfer of information between a coding tag and a recording tag are also disclosed, including single cycle assays.

Abstract: Kits and methods of using the kits for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding are disclosed. The sample analysis kits employ nucleic acid encoding and/or nucleic acid recording of a molecular interaction and/or reaction, such as recognition events (e.g., between an antigen and an antibody, between a modified terminal amino acid residue, or between a small molecule or peptide therapeutic and a target, etc.). Additional barcoding reagents, such as those for cycle-specific barcoding (e.g., “clocking”), compartment barcoding, combinatorial barcoding, spatial barcoding, or any combination thereof, may be included in the kits. The sample may comprise macromolecules, including peptides, polypeptides, and proteins, and the recording may generate molecular interaction and/or reaction information, and/or polypeptide sequence information.

Abstract: A method for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding is disclosed.