Abstract: Compounds represented by Structural Formula (I): are useful, for example, in the effective killing or reducing the rate of proliferation of cancer cells, such as in patients suffering from cancer. In addition to the compounds themselves, the invention provides pharmaceutical compositions of the compounds and method of treatment using the compounds.

Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.

Abstract: A method for centrally providing a profile of a user's degree of preference for one or more items across categories in a plurality of domains of interest in a taxonomy of preferences is described. In one embodiment, the method includes identifying a user's degree of preference for an item from a plurality of indicators. The user's degree of preference for the item is associated with a category in a domain of interest and is stored in a profile of the user. In another embodiment, the profile identifies preferences of the user in a taxonomy of preferences across categories in a plurality of domains of interest.

Abstract: A method for centrally providing a profile of a user's degree of preference for one or more items across categories in a plurality of domains of interest in a taxonomy of preferences is described. In one embodiment, the method includes identifying a user's degree of preference for an item from a plurality of indicators. The user's degree of preference for the item is associated with a category in a domain of interest and is stored in a profile of the user. In another embodiment, the profile identifies preferences of the user in a taxonomy of preferences across categories in a plurality of domains of interest.

Abstract: Existing network-based services can be reused by a new network service providing an updated interface to the existing services. A client request directed to the new network service triggers a back-end request from the new network service to the existing network service. The back-end request comprises aspects of the client's request and additional formatting rules and other information to override specific aspects of the existing network service. The existing network service generates a back-end response with its existing functionality that is being reused, and applies the specified overrides. Additional information to be utilized by the new network service in responding to the client can be added to the back-end response. The new network service can then form and transmit a response to the client by utilizing the central portion of the back-end response and appending additional information to it, including the information specified by the existing network-service.

Abstract: A method of providing a high symbol rate communication system with reduced overhead bandwidth includes calculating a minimum feasible aperture length at a network operations center, setting a hub demodulator subsystem to use an aperture length calculated from the minimum feasible aperture length, broadcasting the aperture length to a VSAT, and receiving an inroute data stream from the VSAT utilizing the aperture length.

Abstract: A neurostimulation array comprising a first implantable neurostimulator storing a first identification code in a non-volatile memory and responding to communications including said first identification code, a second implantable neurostimulator storing a second identification code in a non-volatile memory and responding to communications including said second identification code, and a polymer connector attached to said first implantable neurostimulator and said second implantable neurostimulator, thereby forming a neurostimulation array.

Abstract: Novel methods to identify and characterize glycoproteins that are likely to be found in serum, and that will therefore provide more relevant disease markers than current methods are disclosed. The proteins that are likely to be found in serum are distinguished either by cleavage from the membrane or as potentially secreted proteins characterized by solubility in an aqueous phase. The methods disclosed also allow determination of differential glycosylation patterns of proteins that are likely to be found in serum from cells in various stages of disease. In addition, methods to identify novel therapeutic targets by identifying glycoproteins retained in diseased cells are disclosed.

Abstract: Compounds represented by Structural Formula (I): are useful, for example, in the effective killing or reducing the rate of proliferation of cancer cells, such as in patients suffering from cancer. In addition to the compounds themselves, the invention provides pharmaceutical compositions of the compounds and method of treatment using the compounds.

Abstract: The invention relates to glycoproteins having a cancer-specific glycoform. Cancer-specific glycoforms are useful in diagnostics and therapeutics.

Abstract: A method for centrally providing a profile of a user's degree of preference for one or more items across categories in a plurality of domains of interest in a taxonomy of preferences is described. In one embodiment, the method includes identifying a user's degree of preference for an item from a plurality of indicators. The user's degree of preference for the item is associated with a category in a domain of interest and is stored in a profile of the user. In another embodiment, the profile identifies preferences of the user in a taxonomy of preferences across categories in a plurality of domains of interest.

Abstract: A previously unknown mammalian UDP-N-acetylglucosamine:?-6-D-mannoside ?-1,6-N-acetylglucosaminyl-transferase (termed GlcNAc T-Vb herein) coding sequence, protein, recombinant host cells and antibodies which specifically bind GlcNAc T-Vb are described. In particular, GlcNAc T-Vb of mouse is disclosed.

Abstract: Disclosed are a method and an algorithm for genetic cross-matching based on the comparison of recipient and donor genotypes—and the underlying combinations of alleles and haplotypes. The method of the invention, rather than focusing on phenotype prediction, instead relies on a comparison of genetic variants identified in the recipient and available donors, whose information preferably will be compiled in a widely available donor registry, to maximize molecular compatibility. The genotypes can be matched based on the weighted clinical significance of a genotypic difference between donor and recipient, such that certain mismatches are more acceptable than others.

Abstract: Ultrasound imaging arrangement including an ultrasound scanner, an ultrasound imaging system arranged to control the scanner and at least one display physically separated from the imaging system. A system is provided to enable the transmission of images from the imaging system to each display using IEEE standard 802.15.3. For example, the imaging system and each display may include a network interface card/video card capable of utilizing IEEE standard 802.15.3. The absence of a physical connection between the display(s) and the imaging system allows the display(s) to be freely positionable as desired by the person conducting the examination without limitations imposed by the placement of the imaging system. Multiple displays can be provided, all receiving and displaying the same images.

Abstract: Compounds represented by Structural Formula (I): are useful, for example, in the effective killing or reduction in rate of proliferation of cancer cells, such as in patients suffering from cancer. In addition to the compounds themselves, the invention provides pharmaceutical compositions of the compounds and method of treatment using the compounds.

Abstract: Disclosed are a method and an algorithm for genetic cross-matching based on the comparison of recipient and donor genotypes—and the underlying combinations of alleles and haplotypes. The method of the invention, rather than focusing on phenotype prediction, instead relies on a comparison of genetic variants identified in the recipient and available donors, whose information preferably will be compiled in a widely available donor registry, to maximize molecular compatibility. The genotypes can be matched based on the weighted clinical significance of a genotypic difference between donor and recipient, such that certain mismatches are more acceptable than others.

Abstract: Disclosed are a method and an algorithm for genetic cross-matching based on the comparison of recipient and donor genotypes—and the underlying combinations of alleles and haplotypes. The method of the invention, rather than focusing on phenotype prediction, instead relies on a comparison of genetic variants identified in the recipient and available donors, whose information preferably will be compiled in a widely available donor registry, to maximize molecular compatibility. The genotypes can be matched based on the weighted clinical significance of a genotypic difference between donor and recipient, such that certain mismatches are more acceptable than others.

Abstract: A contextual computer workspace feature provides users with a mechanism to capture and output a state of a contextual computer workspace so that the user may continue working on a computer-based task as though no interruptions occurred. A state of a contextual computer workspace, including the window views and content thereof, is captured. Upon capturing a state of a contextual computer workspace, an indication to access the contextual computer workspace is received. The state of the contextual computer workspace is restored and the restored state is then output to communicate the contextual computer workspace to the user.

Abstract: An ultrasound diagnostic imaging system (10) is provided with its own onboard network analyzer (34). When a problem with a network to which the ultrasound system is connected is discovered, the network analyzer is started on the ultrasound system. A test is run by transmitting DICOM data from the ultrasound system to another device on the network. The network analyzer is operable in a listening mode to produce a capture file of the raw packet data concerning the DICOM transmission and to present the capture file to a user for analysis such as by parsing out the DICOM communication data on the network.

Abstract: An ultrasound system which is capable of sending images and/or reports over a data network by means of an Internet protocol has a sound card coupled to a microphone and a loudspeaker. When operator of the ultrasound system speaks into the microphone the voice is digitized by the sound card and the voice data is packaged as payloads of data packets. The packets are sent over the same data network by a protocol stack using an Internet protocol. The packets are received and returned to analog voice signals at a receiving terminal. The voice capability can reach other terminals on the network or external correspondents by means of the Internet or external networks such as public switched telephone networks.