Patents by Inventor Michael Pirrung

Michael Pirrung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE INSULIN MIMETICS ABSENT QUINONES
    Publication number: 20070232663
    Abstract: Compounds of Formula I are described along with pharmaceutical formulations thereof, and methods of treating disorders such as diabetes and neurodegenerative diseases with such compounds.
    Type: Application
    Filed: March 28, 2007
    Publication date: October 4, 2007
    Inventor: Michael Pirrung
  • Polypeptide array synthesis
    Publication number: 20060194258
    Abstract: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 31, 2006
    Applicant: AFFYMETRIX, INC.
    Inventors: Michael Pirrung, Lubert Stryer, Stephen Fodor, J. Read
  • Electrochemical arrays
    Publication number: 20060094024
    Abstract: The present invention relates to methods for synthesizing nucleic acids. The invention also relates to the production of an array of nucleic acids as well as methods for making such an array. Electrochemical methods may be used to both fabricate and interrogate the nucleic acid arrays.
    Type: Application
    Filed: November 1, 2004
    Publication date: May 4, 2006
    Inventors: Michael Pirrung, H. Thorp
  • Very large scale immobilized polymer synthesis
    Publication number: 20050214828
    Abstract: A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group, is provided to the substrate to bind at the selected areas. The process is repeated using a variety of monomers such as amino acids until sequences of a desired length are obtained. Detection methods and apparatus are also disclosed.
    Type: Application
    Filed: January 21, 2005
    Publication date: September 29, 2005
    Applicant: Affymetrix, INC.
    Inventors: Michael Pirrung, J. Read, Stephen Fodor, Lubert Stryer
  • Very large scale immobilized polymer synthesis
    Publication number: 20050208537
    Abstract: A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protecting groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
    Type: Application
    Filed: December 16, 2004
    Publication date: September 22, 2005
    Applicant: Affymetrix, INC.
    Inventors: Stephen Fodor, Lubert Stryer, Michael Pirrung, J. Read
  • Polymer arrays
    Publication number: 20050153362
    Abstract: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
    Type: Application
    Filed: November 23, 2004
    Publication date: July 14, 2005
    Inventors: Michael Pirrung, Lubert Stryer, Stephen Fodor, J. Read
  • Polymer arrays
    Publication number: 20050153363
    Abstract: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
    Type: Application
    Filed: November 23, 2004
    Publication date: July 14, 2005
    Inventors: Michael Pirrung, Lubert Stryer, Stephen Fodor, J. Read
  • Very large scale immobilized polymer synthesis
    Publication number: 20050148027
    Abstract: A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group, is provided to the substrate to bind at the selected areas. The process is repeated using a variety of monomers such as amino acids until sequences of a desired length are obtained. Detection methods and apparatus are also disclosed.
    Type: Application
    Filed: November 23, 2004
    Publication date: July 7, 2005
    Applicant: Affymetrix Inc.
    Inventors: Michael Pirrung, J. Read, Stephen Fodor, Lubert Stryer
  • Polymer arrays
    Publication number: 20050118706
    Abstract: The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
    Type: Application
    Filed: November 23, 2004
    Publication date: June 2, 2005
    Applicant: AFFYMETRIX, INC.
    Inventors: Michael Pirrung, Lubert Stryer, Stephen Fodor, J. Read
  • Apparatus comprising polymers
    Publication number: 20050095652
    Abstract: A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protecting groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
    Type: Application
    Filed: November 23, 2004
    Publication date: May 5, 2005
    Applicant: Affymetrix, Inc.
    Inventors: Stephen Fodor, Lubert Stryer, Michael Pirrung, J. Read, Paul Hoeprich
  • Very large scale immobilized polymer synthesis
    Publication number: 20050079529
    Abstract: A synthetic strategy for the creation of large scale chemical diversity. Solid-phase chemistry, photolabile protecting groups, and photolithography are used to achieve light-directed spatially-addressable parallel chemical synthesis. Binary masking techniques are utilized in one embodiment. A reactor system, photoremovable protecting groups, and improved data collection and handling techniques are also disclosed. A technique for screening linker molecules is also provided.
    Type: Application
    Filed: August 27, 2004
    Publication date: April 14, 2005
    Applicant: Affymetrix, INC.
    Inventors: Stephen Fodor, Lubert Stryer, Michael Pirrung, J. Reed, Paul Hoeprich
  • Method of attaching a biopolymer to a solid support
    Publication number: 20050032084
    Abstract: The present invention relates, in general, to a method of attaching a biopolymer to a solid support and, in particular, to a method of attaching a nucleic acid to a glass surface, and to reagents suitable for use in such a method. The invention further relates to the product produced by the present method and to kits comprising same.
    Type: Application
    Filed: January 8, 2004
    Publication date: February 10, 2005
    Applicant: DUKE UNIVERSITY
    Inventors: Michael Pirrung, Amy Odenbaugh, Richard Connors, Janice Worden