Patents by Inventor Michael Pohlscheidt

Michael Pohlscheidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220143562
    Abstract: The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveying element is equal to or less than the inner diameter di of the radially-conveying element. In one embodiment the stirrer according to the invention is a combination of one anchor stirrer with at least one inclined-blade stirrer. Furthermore the use of the stirrer according to the invention for the culture of cells in a dialysis method is described.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 12, 2022
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Marco JENZSCH, Max LECHNER, Michael POHLSCHEIDT, Christoph REESE, Alexander SCHOLZ, Hermann TEBBE
  • Patent number: 11253826
    Abstract: The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveying element is equal to or less than the inner diameter di of the radially-conveying element. In one embodiment the stirrer according to the invention is a combination of one anchor stirrer with at least one inclined-blade stirrer. Furthermore the use of the stirrer according to the invention for the culture of cells in a dialysis method is described.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: February 22, 2022
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Marco Jenzsch, Max Lechner, Michael Pohlscheidt, Christoph Reese, Alexander Scholz, Hermann Tebbe
  • Publication number: 20200406168
    Abstract: Separating apparatus, comprising a sedimentation settler and a collection vessel disposed underneath and being in fluid communication with the sedimentation settler, the collection vessel forming a receiving chamber having an outlet at or adjacent to the chamber bottom and having an inlet opening, wherein the collection vessel is arranged such the flow direction of the fluid in the area underneath the sedimentation settler is substantially in line with the direction of the channels of the sedimentation settler.
    Type: Application
    Filed: June 11, 2020
    Publication date: December 31, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Oskar BRAUNERSREUTHER, Alexander JOCKWER, Torsten KLABUHN, Michael POHLSCHEIDT, Joerg THIELE
  • Patent number: 10702800
    Abstract: Separating apparatus, comprising a sedimentation settler and a collection vessel disposed underneath and being in fluid communication with the sedimentation settler, the collection vessel forming a receiving chamber having an outlet at or adjacent to the chamber bottom and having an inlet opening, wherein the collection vessel is arranged such the flow direction of the fluid in the area underneath the sedimentation settler is substantially in line with the direction of the channels of the sedimentation settler.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: July 7, 2020
    Assignee: Hoffman-La Roche Inc.
    Inventors: Oskar Braunersreuther, Alexander Jockwer, Torsten Klabuhn, Michael Pohlscheidt, Joerg Thiele
  • Publication number: 20190168177
    Abstract: The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveying element is equal to or less than the inner diameter di of the radially-conveying element. In one embodiment the stirrer according to the invention is a combination of one anchor stirrer with at least one inclined-blade stirrer. Furthermore the use of the stirrer according to the invention for the culture of cells in a dialysis method is described.
    Type: Application
    Filed: August 14, 2018
    Publication date: June 6, 2019
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Marco JENZSCH, Max LECHNER, Michael POHLSCHEIDT, Christoph REESE, Alexander SCHOLZ, Hermann TEBBE
  • Patent number: 10076731
    Abstract: The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveying element is equal to or less than the inner diameter di of the radially-conveying element. In one embodiment the stirrer according to the invention is a combination of one anchor stirrer with at least one inclined-blade stirrer. Furthermore the use of the stirrer according to the invention for the culture of cells in a dialysis method is described.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: September 18, 2018
    Assignee: HOFFMAN-LA ROCHE INC.
    Inventors: Marco Jenzsch, Max Lechner, Michael Pohlscheidt, Christoph Reese, Alexander Scholz, Hermann Tebbe
  • Publication number: 20180187138
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: November 1, 2017
    Publication date: July 5, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius
  • Publication number: 20170157539
    Abstract: Separating apparatus, comprising a sedimentation settler and a collection vessel disposed underneath and being in fluid communication with the sedimentation settler, the collection vessel forming a receiving chamber having an outlet at or adjacent to the chamber bottom and having an inlet opening, wherein the collection vessel is arranged such the flow direction of the fluid in the area underneath the sedimentation settler is substantially in line with the direction of the channels of the sedimentation settler.
    Type: Application
    Filed: February 23, 2017
    Publication date: June 8, 2017
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Oskar Braunersreuther, Alexander Jockwer, Torsten Klabuhn, Michael Pohlscheidt, Joerg Thiele
  • Publication number: 20150175952
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: November 26, 2014
    Publication date: June 25, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius
  • Publication number: 20140057344
    Abstract: Separating apparatus, comprising a sedimentation settler and a collection vessel disposed underneath and being in fluid communication with the sedimentation settler, the collection vessel forming a receiving chamber having an outlet at or adjacent to the chamber bottom and having an inlet opening, wherein the collection vessel is arranged such the flow direction of the fluid in the area underneath the sedimentation settler is substantially in line with the direction of the channels of the sedimentation settler.
    Type: Application
    Filed: July 15, 2013
    Publication date: February 27, 2014
    Inventors: Oskar Brauner-Sreuther, Alexander Jockwear, Torsten Klabuhn, Michael Pohlscheidt, Joerg Thiele
  • Publication number: 20120135464
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 31, 2012
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius
  • Publication number: 20120070860
    Abstract: The present patent application describes a stirrer comprising a combination of at least one axially-conveying element and at least one radially-conveying element relative to the rotary shaft of the stirrer wherein the largest diameter of the at least one axially-conveying element is equal to or less than the inner diameter di of the radially-conveying element. In one embodiment the stirrer according to the invention is a combination of one anchor stirrer with at least one inclined-blade stirrer. Furthermore the use of the stirrer according to the invention for the culture of cells in a dialysis method is described.
    Type: Application
    Filed: June 2, 2010
    Publication date: March 22, 2012
    Inventors: Marco Jenzsch, Max Lechner, Michael Pohlscheidt, Christoph Reese, Alexander Scholz, Hermann Tebbe
  • Patent number: 7666654
    Abstract: The invention relates to a method for preparing viral suspensions. The invention relates in particular to a method for preparing high-titer viral suspensions in cell cultures. Preferred methods include increasing the volume of the cell culture prior to infection with viral material and subsequent further steps of expanding the volume to a final volume which is distinctly larger than the maximum culture volume prior to infection.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: February 23, 2010
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Michael Pohlscheidt, Berthold Boedeker, Torsten Minuth, Heiner Apeler, Uwe Langer, Katrin Brabender, Dirk Otto-Brabender, Joachim Kerper, Hans-Juergen Henzler
  • Publication number: 20080014626
    Abstract: The invention relates to a method for preparing viral suspensions. The invention relates in particular to a method for preparing high-titer viral suspensions in cell cultures. Preferred methods include increasing the volume of the cell culture prior to infection with viral material and subsequent further steps of expanding the volume to a final volume which is distinctly larger than the maximum culture volume prior to infection.
    Type: Application
    Filed: April 5, 2007
    Publication date: January 17, 2008
    Inventors: Michael Pohlscheidt, Berthold Boedeker, Torsten Minuth, Heiner Apeler, Uwe Langer, Katrin Brabender, Dirk Otto-Brabender, Joachim Kerper, Hans-Juergen Henzler