Patents by Inventor Michael Polydefkis

Michael Polydefkis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantitation of GCP activity in biological samples
    Patent number: 8771975
    Abstract: Provided herein are methods for quantitating glutamate carboxypeptidase II activity in a biological sample, such as a skin biopsy sample, and for determining whether an agent is inhibiting GCP in a subject.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: July 8, 2014
    Assignee: The Johns Hopkins University
    Inventors: Barbara S. Slusher, Michael Polydefkis, Camilo Rojas, Marigo Stathis
  • Quantitation of GCP Activity in Biological Samples
    Publication number: 20130344525
    Abstract: Provided herein are methods for quantitating glutamate carboxypeptidase II activity in a biological sample, such as a skin biopsy sample, and for determining whether an agent is inhibiting GCP in a subject.
    Type: Application
    Filed: January 5, 2012
    Publication date: December 26, 2013
    Applicant: 6The Hohns Hopkins University
    Inventors: Barbara S. Slusher, Michael Polydefkis, Camilo Rojas, Marigo Stathis
  • Device for thermal stimulation of small neural fibers
    Publication number: 20040243021
    Abstract: A device operable to assess temperature response of small neural fibers. The device includes a heat source. A skin contacting probe tip that includes at least one skin contacting region is operatively connected to the heat source and operable to apply a heat to regions of skin having varying surface areas. A temperature sensor is arranged in the vicinity of the probe tip and is operable to detect a temperature of the probe tip. A controller is operatively connected to the heat source and the temperature sensor to maintain a target temperature of the probe tip.
    Type: Application
    Filed: May 5, 2004
    Publication date: December 2, 2004
    Inventors: John C. Murphy, Rafal P Szczepanowski, Wolfger Schneider, Richard A Meyer, Justin C McArthur, Michael Polydefkis