Patents by Inventor Michael PRIESCHL

Michael PRIESCHL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS
    Publication number: 20260242370
    Abstract: The present disclosure relates to a continuous flow process for synthesis of heterocyclic methanone compounds, and in particular 3-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds, and aza-bicyclo intermediates thereof. In particular, the present disclosure also relates to a continuous flow process that can be utilised toward the synthesis of Xanamem.
    Type: Application
    Filed: March 1, 2024
    Publication date: August 20, 2026
    Inventors: Jason Douglas WILLIAMS, Michael PRIESCHL
  • PROCESS FOR THE PREPARATION OF A CHIRAL PYRROLO TRIAZOLE ALCOHOL
    Publication number: 20260159522
    Abstract: The invention relates to a novel process for the preparation of chiral pyrrolo triazole alcohols of the formula I wherein X is a halogen atom, n is an integer of 1, 2 or 3 and wherein the spiral bond “” stands for “” or for “” or mixtures of the enantiomers. The chiral pyrrolo triazole alcohols of the formula I are versatile intermediates for the preparation of compounds that have the potential to serve as active pharmaceutical ingredients in drugs.
    Type: Application
    Filed: December 10, 2025
    Publication date: June 11, 2026
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Stephan BACHMANN, Raphael BIGLER, Serena BISAGNI, Dainis KALDRE, Christian Oliver KAPPE, Michael PRIESCHL, Kurt PUENTENER, Rosa Maria RODRIGUEZ SARMIENTO, Joerg SEDELMEIER, Jason Douglas WILLIAMS
  • PROCESS FOR PREPARING 1-[5-TERT-BUTYL-3-[(1-METHYLTETRAZOL-5-YL)METHYL]TRIAZOLO[4,5-D]PYRIMIDIN-7-YL]PYRROLIDIN-3-OL
    Publication number: 20250326759
    Abstract: The present invention relates to a process for the preparation of (3S)-1-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]-6,7-dihydrotriazolo[4,5-d]pyrimidin-7-yl] pyrrolidin-3-ol useful as pharmaceutically active compounds.
    Type: Application
    Filed: December 5, 2024
    Publication date: October 23, 2025
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jean-Michel ADAM, Dainis KALDRE, Christian Oliver KAPPE, Christian Steffen MOESSNER, Michael PRIESCHL, Peter SAGMEISTER, Joerg Mathias SEDELMEIER, Sebastian TROKOWSKI, Jason Douglas WILLIAMS