Patents by Inventor Michael Quirmbach

Michael Quirmbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydro-imidazo [1,5-A] pyridyin derivatives as aldosterone synthase inhibitors
    Patent number: 8680079
    Abstract: The application relates to novel heterocyclic compounds of the general formula (I) in which R, R1, R2, X, Y, Z and n have the meanings defined in the description, to a process for their preparation and to the use of these compounds as medicaments, in particular as aldosterone synthase inhibitors.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: March 25, 2014
    Assignee: Novartis AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Christoph Schumacher, Michael Quirmbach
  • Bis-heterocyclic imidazolyl compounds
    Patent number: 8263615
    Abstract: Heterocyclic compounds of the general formula (I) are provided in which R, R1, R2, R3, R4 and n have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldostereone synthase inhibitors,
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: September 11, 2012
    Assignee: Novartis AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Michael Quirmbach, Christiane Marti, Aleksandar Stojanovic, Stefan Stutz
  • 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
    Publication number: 20120115859
    Abstract: The application relates to novel substituted piperidines of the general formula (II) in which R1?, R2?, R2?, R4?, X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.
    Type: Application
    Filed: January 13, 2012
    Publication date: May 10, 2012
    Inventors: Peter HEROLD, Robert Mah, Vincenzo Tschinke, Nathalie Jotterand, Dirk Behnke, Aleksandar Stojanovic, Stefan Stutz, Michael Quirmbach, Stjepan Jelakovic
  • Heterocyclic spiro-compounds as aldosterone synthase inhibitors
    Patent number: 8071774
    Abstract: The patent application relates to new heterocyclic compounds of the general formula (I) in which A, R, R1, R2, U, V, W, X, Y, Z, n and p have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: December 6, 2011
    Assignee: Novartis AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Christiane Marti, Nathalie Jotterand, Christoph Schumacher, Michael Quirmbach
  • Heterocyclic spiro-compounds as aldosterone synthase inhibitors
    Patent number: 8071773
    Abstract: The patent application relates to new heterocyclic compounds of the general formula (I) in which R, R1, R2, W, X, Y, Z and n have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: December 6, 2011
    Assignee: NovartisAG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Christiane Marti, Nathalie Jotterand, Christoph Schumacher, Michael Quirmbach
  • Bis-heterocyclic imidazolyl compounds
    Patent number: 8008334
    Abstract: The patent application relates to new heterocyclic compounds of the general formula (I) in which R, R1, R2, R3, R4 and n have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: August 30, 2011
    Assignee: Novartis AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Michael Quirmbach, Christiane Marti, Aleksandar Stojanovic, Stefan Stutz
  • BIS-HETEROCYCLIC IMIDAZOLYL COMPOUNDS
    Publication number: 20110028512
    Abstract: Heterocyclic compounds of the general formula (I) are provided in which R, R1, R2, R3, R4 and n have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldostereone synthase inhibitors,
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Michael Quirmbach, Christiane Marti, Aleksandar Stojanovic, Stefan Stutz
  • Organic compounds
    Patent number: 7868036
    Abstract: The invention relates to novel amino alcohols of the general formula (I) where X, R1, R2, R3, R4, R5 and R6 are each as defined in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: January 11, 2011
    Assignee: Novartis AG
    Inventors: Peter Herold, Stefan Stutz, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Nathalie Jotterand, Michael Quirmbach, Dirk Behnke, Christiane Marti
  • 5-amino 4-hydroxy-7-(1H-indolmethyl)-8-methylnonamide derivatives as renin inhibitors for the treatment of hypertension
    Patent number: 7851634
    Abstract: The application relates to novel alkanamides of the general formula (I) where X is —CH2— or >CH—OH; (A) R1 is e.g.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: December 14, 2010
    Assignee: Novartis AG
    Inventors: Peter Herold, Stefan Stutz, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Nathalie Jotterand, Michael Quirmbach, Dirk Behnke, Christiane Marti
  • Substituted piperidines as renin inhibitors
    Patent number: 7799779
    Abstract: Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: September 21, 2010
    Assignee: Novartis AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Dirk Behnke, Christiane Marti, Nathalie Jotterand, Stefan Stutz, Michael Quirmbach
  • Amino alcohol derivatives and their activity as renin inhibitors
    Patent number: 7786307
    Abstract: The application relates to novel amino alcohols of general formula (I) where R, R1, R2, R3, R4, R5, X1 and X2 each have the definitions illustrated in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: August 31, 2010
    Assignee: Novartis AG
    Inventors: Peter Herold, Stefan Stutz, Aleksandar Stojanovic, Vincenzo Tschinke, Christiane Marti, Michael Quirmbach
  • Amino alcohol derivatives and their use as renin inhibitor
    Patent number: 7767690
    Abstract: The application relates to novel amino alcohols of the general formula (I) where R, R1, R2, R3, R4, R5 and R6 each have the definitions illustrated in detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: August 3, 2010
    Assignee: Novartis AG
    Inventors: Peter Herold, Stefan Stutz, Aleksandar Stojanovic, Vincenzo Tschinke, Christiane Marti, Michael Quirmbach
  • FUSED IMIDAZOLE DERIVATIVES AND USE THEREOF AS ALDOSTERONE SYNTHASE INHIBITORS
    Publication number: 20100168145
    Abstract: The patent application relates to new heterocyclic compounds of the general formula (I) in which A, R, R1, R2, X, Y, Z, n and p have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
    Type: Application
    Filed: May 30, 2006
    Publication date: July 1, 2010
    Applicant: SPEEDEL EXPERIMENTA AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Christiane Marti, Nathalie Jotterand, Christoph Schumacher, Michael Quirmbach
  • Diamino alcohols and their use as renin inhibitor
    Patent number: 7718675
    Abstract: The application relates to novel amino alcohols of the general formula (I) where R, R1, R2, R3, R4, R5 and R6 each have the definitions illustrated in detail in the description, to a process for their preparation, and to the use of these compounds as medicines, in particular as renin inhibitors.
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: May 18, 2010
    Assignee: Speedel Experimenta AG
    Inventors: Peter Herold, Stefan Stutz, Aleksandar Stojanovic, Vincenzo Tschinke, Christiane Marti, Michael Quirmbach
  • Substituted piperidines
    Patent number: 7687495
    Abstract: Substituted piperidines of formulae (I) and (II) with the substituent definitions as explained in the specification. The compounds are suitable in particular as renin inhibitors and are highly potent.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: March 30, 2010
    Assignee: Speedel Experimenta AG
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Christiane Marti, Stefan Stutz, Stjepan Jelakovic, Zenon D. Konteatis, Jennifer L. Ludington, Michael Quirmbach, Aleksandar Stojanovic, Dirk Behnke, Frank Hollinger
  • 2,4,5-Substituted Piperidines as Renin Inhibitors
    Publication number: 20100029628
    Abstract: SP-P2140 ATE-132—Abstract Novel substituted piperidines of the general formula (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent.
    Type: Application
    Filed: March 30, 2006
    Publication date: February 4, 2010
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Christiane Marti, Stefan Stutz, Stjepan Jelakovic, Zenon D. Konteatis, Jennifer L. Ludington, Michael Quirmbach, Aleksandar Stojanovic, Dirk Behnke, Frank Hollinger
  • Heterocyclic compounds and their use as aldosterone synthase inhibitors
    Publication number: 20100029694
    Abstract: Heterocyclic compounds of the general formula (I) in which R, R1, R2, W, X, Y, Z and n have the meanings defined in the description, a process for their preparation and the use of these compounds as medicaments, in particular as aldosterone synthase inhibitors.
    Type: Application
    Filed: September 18, 2009
    Publication date: February 4, 2010
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Christoph Schumacher, Michael Quirmbach
  • Heterocyclic spiro-compounds as aldosterone synthase inhibitors
    Publication number: 20100010015
    Abstract: The patent application relates to new heterocyclic compounds of the general formula (I) in which A, R, R1, R2, U, V, W, X, Y, Z, n and p have the definitions elucidated in more detail in the description, to a process for preparing them and to the use of these compounds as medicaments, particularly as aldosterone synthase inhibitors.
    Type: Application
    Filed: May 30, 2006
    Publication date: January 14, 2010
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Aleksandar Stojanovic, Christiane Marti, Nathalie Jotterand, Christoph Schumacher, Michael Quirmbach
  • Substituted Piperidines as Renin Inhibitors
    Publication number: 20090306064
    Abstract: Compounds of the general formula (I) in which the meanings of the substituents R1, R2, R3, R4, X, Z and n as stated in claim 1 have renin-inhibiting properties and can be used as medicines.
    Type: Application
    Filed: March 30, 2006
    Publication date: December 10, 2009
    Inventors: Peter Herold, Robert Mah, Vincenzo Tschinke, Dirk Behnke, Christiane Marti, Nathalie Jotterand, Stefan Stutz, Michael Quirmbach
  • 2,5-Disubstituted Piperidines
    Publication number: 20090306062
    Abstract: The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R1 and X are each as defined in detail in the description, and pharmaceutical preparations comprising these compounds.
    Type: Application
    Filed: June 7, 2007
    Publication date: December 10, 2009
    Inventors: Peter Herold, Robert Mah, Stefan Stutz, Vincenzo Tschinke, Isabelle Lyothier, Stjepan Jelakovic, Michael Quirmbach, Christiane Marti