Patents by Inventor Michael R. Berke

Michael R. Berke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11733251
    Abstract: Methods and systems of performing an assay. A system for performing an assay includes an enclosure defining a temperature-controlled space. An imaging system, an actuator and a dispenser are disposed within the space. The actuator receives a well plate having wells. The actuator is to move the well plate relative to the imaging system to enable the imaging system to obtain image data of one of the wells. The dispenser includes a pump, an outlet and a reservoir holder to receive a reservoir containing a compound. The pump is to be fluidly coupled to the reservoir and an outlet. The pump is to pump the compound from the reservoir through the outlet into one of the wells. The system also includes a controller. The controller is to cause the dispenser to dispense the compound into the first one of the wells while the imaging system obtains the image data.
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: August 22, 2023
    Assignee: AMGEN INC.
    Inventors: Brandon Zachary Sarich, Michael R. Berke, Chuck Z. Li, Thomas Clark Pearson
  • Publication number: 20220137061
    Abstract: Systems and methods that facilitate the automatic (or substantially automatic) preparation of a sample of a product containing molecules for analysis and automatic (or substantially automatic) performance of an assay of that sample. Thus, the preparation and analysis can be performed substantially in-real time, or, in other words, much more quickly than presently allowed by conventional systems and methods.
    Type: Application
    Filed: February 14, 2020
    Publication date: May 5, 2022
    Inventors: Chao-Hsiang Wu, Gang Xue, Brandon Zachary Sarich, Michael R. Berke, Jacob Sebastain, Pik Chan
  • Publication number: 20200249248
    Abstract: Methods and systems of performing an assay. A system for performing an assay includes an enclosure defining a temperature-controlled space. An imaging system, an actuator and a dispenser are disposed within the space. The actuator receives a well plate having wells. The actuator is to move the well plate relative to the imaging system to enable the imaging system to obtain image data of one of the wells. The dispenser includes a pump, an outlet and a reservoir holder to receive a reservoir containing a compound. The pump is to be fluidly coupled to the reservoir and an outlet. The pump is to pump the compound from the reservoir through the outlet into one of the wells. The system also includes a controller. The controller is to cause the dispenser to dispense the compound into the first one of the wells while the imaging system obtains the image data.
    Type: Application
    Filed: January 14, 2020
    Publication date: August 6, 2020
    Inventors: Brandon Zachary Sarich, Michael R. Berke, Chuck Z. Li, Thomas Clark Pearson