Patents by Inventor Michael R. Carrasco

Michael R. Carrasco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial corneal implant
    Publication number: 20110184513
    Abstract: A material that can be applied as implants designed to artificially replace or augment the cornea, such as an artificial cornea, corneal onlay, or corneal inlay (intrastromal lens) is provided. The artificial corneal implant has a double network hydrogel with a first network interpenetrated with a second network. The first network and the second network are based on biocompatible polymers. At least one of the network polymers is based on a hydrophilic polymer. The artificial cornea or implant has epithelialization promoting biomolecules that are covalently linked to the surface of the double network hydrogel using an azide-active-ester chemical linker. Corneal epithelial cells or cornea-derived cells are adhered to the biomolecules. The double network has a physiologic diffusion coefficient to allow passage of nutrients to the adhered cells.
    Type: Application
    Filed: December 20, 2010
    Publication date: July 28, 2011
    Inventors: David Myung, Jaan Noolandi, Alan J. Smith, Curtis W. Frank, Christopher N. Ta, Yin Hu, Won-Gun Koh, Michael R. Carrasco, Laura Hartmann
  • Artificial corneal implant
    Patent number: 7857849
    Abstract: A material that can be applied as implants designed to artificially replace or augment the cornea, such as an artificial cornea, corneal onlay, or corneal inlay (intrastromal lens) is provided. The artificial corneal implant has a double network hydrogel with a first network interpenetrated with a second network. The first network and the second network are based on biocompatible polymers. At least one of the network polymers is based on a hydrophilic polymer. The artificial cornea or implant has epithelialization promoting biomolecules that are covalently linked to the surface of the double network hydrogel using an azide-active-ester chemical linker. Corneal epithelial cells or cornea-derived cells are adhered to the biomolecules. The double network has a physiologic diffusion coefficient to allow passage of nutrients to the adhered cells.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: December 28, 2010
    Assignees: The Board of Trustees of the Leland Stanford Junior Iniversity, Santa Clara University
    Inventors: David Myung, Jaan Noolandi, Alan J. Smith, Curtis W. Frank, Christopher Ta, Yin Hu, Won-Gun Koh, Michael R. Carrasco