Patents by Inventor Michael R. Cohen

Michael R. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating depression with thiourea derivatives
    Patent number: 4169154
    Abstract: A method of utilizing thiourea derivatives of the formulas ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3 and X are as hereinafter described, as agents in the treatment of depression, is described.
    Type: Grant
    Filed: September 25, 1978
    Date of Patent: September 25, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael R. Cohen, Richard W. Kierstead, Jefferson W. Tilley
  • Method of treating hypertension
    Patent number: 4161520
    Abstract: A method is disclosed for treating hypertension in warm-blooded animals by the oral administration, to an animal in need of such treatment, of a therapeutically effective dose for example, from about, 0.1 to 5 mg/kg/day as chronic administration or 5 to 10 mg/kg/day, of a polyether compound such as bromolasalocid or bromoisolasalocid. Also disclosed are examples of such polyether compounds and methods for their preparation.
    Type: Grant
    Filed: October 14, 1976
    Date of Patent: July 17, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Melville W. Osborne, Michael R. Cohen
  • Method of reducing blood pressure with thiourea derivatives and guanidine derivatives
    Patent number: 4150138
    Abstract: Antihypertensively active thiourea derivatives of the formulas ##STR1## wherein R, R.sub.1, R.sub.2, R.sub.3 and X are as hereinafter described, as well as a method of using a compound of the formula ##STR2## wherein R.sub.1 ', R.sub.2 ', R.sub.3 and X are as previously described, or a compound of formula II as an anti-hypertensive agent, is described.
    Type: Grant
    Filed: March 6, 1978
    Date of Patent: April 17, 1979
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Michael R. Cohen, Richard W. Kierstead, Jefferson W. Tilley