Patents by Inventor Michael R. Emmett

Michael R. Emmett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for the preparation of zuclomiphene and intermediates thereof
    Patent number: 11046638
    Abstract: The present invention provides processes for the preparation of zuclomiphene, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the carbometallation of diphenylacetylene with a compound of Formula (3) to afford either zuclomiphene or an intermediate which is converted to zuclomiphene.
    Type: Grant
    Filed: November 11, 2020
    Date of Patent: June 29, 2021
    Assignee: Apotex Inc.
    Inventors: Avedis Karadeolian, Fabio E. S. Souza, Michael R. Emmett, Allan W. Rey
  • Processes for the Preparation of Zuclomiphene and Intermediates Thereof
    Publication number: 20210147337
    Abstract: The present invention provides processes for the preparation of zuclomiphene, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the carbometallation of diphenylacetylene with a compound of Formula (3) to afford either zuclomiphene or an intermediate which is converted to zuclomiphene.
    Type: Application
    Filed: November 11, 2020
    Publication date: May 20, 2021
    Inventors: Avedis Karadeolian, Fabio E. S. Souza, Michael R. Emmett, Allan W. Rey
  • Processes for the preparation of Tezacaftor and intermediates thereof
    Patent number: 10875846
    Abstract: The present invention provides processes for the preparation of Tezacaftor, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the preparation of a compound of Formula (3), and its conversion to Tezacaftor (1).
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: December 29, 2020
    Assignee: Apotex Inc.
    Inventors: Michael R. Emmett, Prabhudas Bodhuri, Yajun Zhao, Eduardo Gustavo Cammisa, Stuart P. Green
  • Processes for the Preparation of Tezacaftor and Intermediates Thereof
    Publication number: 20200223832
    Abstract: The present invention provides processes for the preparation of Tezacaftor, as well as intermediates useful in the preparation thereof. In particular, processes are provided for the preparation of a compound of Formula (3), and its conversion to Tezacaftor (1).
    Type: Application
    Filed: January 13, 2020
    Publication date: July 16, 2020
    Inventors: Michael R. Emmett, Prabhudas Bodhuri, Yajun Zhao, Eduardo Gustavo Cammisa, Stuart P. Green
  • Processes for the preparation of apalutamide and intermediates thereof
    Patent number: 10513504
    Abstract: The present invention provides processes for the preparation of Apalutamide (1), as well as intermediates useful in the preparation thereof. In particular, the process of the invention utilizes the intermediate compound of Formula (2), wherein G is OH or a leaving group, which provides improvements over the known processes for the preparation of Apalutamide (1).
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 24, 2019
    Assignee: Apotex Inc.
    Inventors: Prabhudas Bodhuri, Alfredo Paul Ceccarelli, Michael R. Emmett, Avedis Karadeolian, Fabio E. S. Souza, Gamini Weeratunga, Boris Gorin
  • Processes for the Preparation of Apalutamide and Intermediates Thereof
    Publication number: 20190276424
    Abstract: The present invention provides processes for the preparation of Apalutamide (1), as well as intermediates useful in the preparation thereof. In particular, the process of the invention utilizes the intermediate compound of Formula (2), wherein G is OH or a leaving group, which provides improvements over the known processes for the preparation of Apalutamide (1).
    Type: Application
    Filed: March 6, 2019
    Publication date: September 12, 2019
    Inventors: Prabhudas Bodhuri, Alfredo Paul Ceccarelli, Michael R. Emmett, Avedis Karadeolian, Fabio E. S. Souza, Gamini Weeratunga, Boris Gorin