Abstract: The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with dysregulation of the complement alternative pathway by administering a Complement Factor B (CFB) specific inhibitor to a subject.

Abstract: A power usage simulator generates, for all the logic cells in a circuit cell library, a power model that characterizes a cell's power consumption behavior as a two-part, piecewise-linear function based on signal slew rates and output load. A logic simulator is modified so that for each signal transition in a specified logic circuit, the logic simulator performs a power usage computation utilizing the power usage model for all cells affected by each signal transition. The power usage value for each signal transition is posted to a power usage output data structure, with each posted power usage value having an associated time value. The posted power usage values are then analyzed by (A) accumulating the posted power usage values to provide a total power usage value, and (B) clocking the accumulation of power usage values with an end user set clock rate so as to produce a power usage profile indicating the time varying rate of power consumption during the simulation time period.

Abstract: A swing training and exercise apparatus used by a swinger for practicing and exercising swing motions. The swing training apparatus has a tubular, generally rectangular framework (10). A first handle (30) is on the inboard end (11a) of the upper member 11 of the framework (10), and an end of a second handle (40) is attached at an obtuse angle to framework (10) between the horizontal upper member (11) and a vertical inboard member (13) of framework (10). The area enclosed by the framework (10) is covered by an air resistant material (20) attached thereto for providing drag that opposes the swing motion. The amount of drag is dependent on the material chosen, the percentage of the enclosed area covered by air resistant material (20), and the aspect ratio of the plane of the framework (10) and material (20) to the path of the swing enabling the swinger to practice and build up muscles and muscle memory needed to effect a good, proper swing.