Patents by Inventor Michael R. Pavia

Michael R. Pavia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
    Patent number: 4910312
    Abstract: Selected analogs of nipecotic acid are the novel compounds of the present invention. The analogs are GABA uptake inhibitors for use to treat epilepsy and, thus, the invention is also pharmaceutical compositions and methods of use therefor.
    Type: Grant
    Filed: June 16, 1988
    Date of Patent: March 20, 1990
    Assignee: Warner-Lambert Company
    Inventor: Michael R. Pavia
  • Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
    Patent number: 4826860
    Abstract: A series of substituted 2-aminobenzothiazoles and derivatives useful for treating cerebrovascular disorders are disclosed. Also disclosed is a new method for treating such disorders.
    Type: Grant
    Filed: January 25, 1988
    Date of Patent: May 2, 1989
    Assignee: Warner-Lambert Company
    Inventors: Graham Johnson, Michael R. Pavia
  • Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
    Patent number: 4772615
    Abstract: Analogs of nipecotic acid are the novel compounds of the present invention. The analogs are GABA uptake inhibitors for use to treat epilepsy and, thus, the invention is also pharmaceutical compositions and methods of use therefor.
    Type: Grant
    Filed: October 14, 1987
    Date of Patent: September 20, 1988
    Assignee: Warner-Lambert Company
    Inventor: Michael R. Pavia
  • 1,2,3,4-tetrahydro-2-oxo-8-quinolineacetic and -propanoic acids and derivatives as cognition activators
    Patent number: 4677112
    Abstract: Benzobicyclic lactam acids having a fused aromatic carbocyclic and a saturated lactam ring of five- or six-members, their salts, esters, and amides, are useful in the treatment of senility and for reversing amnesia. Pharmaceutical compositions including these compounds, a method of preparing the compounds, and a method of treating senility and reversing amnesia area also disclosed.
    Type: Grant
    Filed: November 22, 1985
    Date of Patent: June 30, 1987
    Assignee: Warner-Lambert Company
    Inventors: Donald E. Butler, Michael R. Pavia, Fred M. Hershenson
  • Benzobicyclic lactam acids and derivatives as cognition activators
    Patent number: 4582909
    Abstract: Benzobicyclic lactam acids having a fused aromatic carbocyclic and a saturated lactam ring of five- or six-members, their salts, esters, and amides, are useful for reversing amnesia. Pharmaceutical compositions including these compounds, a method of preparing the compounds, and a method of treating senility and reversing amnesia are also disclosed.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: April 15, 1986
    Assignee: Warner-Lambert Company
    Inventors: Donald E. Butler, Michael R. Pavia, Fred M. Hershenson
  • Benzotricyclic nitrogen-containing diones and their use in reversing electroconvulsive shock-induced amnesia
    Patent number: 4530929
    Abstract: A class of novel fused-ring, benzotricyclic, nitrogen-containing diones useful as agents in reversing electroconvulsive shock-induced amnesia. A method of preparing the compounds, pharmaceutical compositions including the compounds, and a method of reversing electroconvulsive shock-induced amnesia are disclosed.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: July 23, 1985
    Assignee: Warner-Lambert Company
    Inventors: Donald E. Butler, Michael R. Pavia, Fred M. Hershenson
  • N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
    Patent number: 4525476
    Abstract: N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids, base addition salts, esters, and amides are useful as cognition activators. Pharmaceutical compositions containing these compounds and methods of using the pharmaceutical compositions for treating senility or amnesia are also disclosed.
    Type: Grant
    Filed: May 26, 1983
    Date of Patent: June 25, 1985
    Assignee: Warner-Lambert Company
    Inventors: Donald E. Butler, Fred M. Hershenson, Michael R. Pavia